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Study of Nervous System

Mov Disord: Is it possible to suffer from Parkinson's, check glutathione and take a look

 Time of Update: 2021-11-13

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diagnosisOriginal sourcePlasma Glutathione and Prodromal Parkinson's Disease Probability [published online ahead of print, 2021 Oct 25]. 28826Plasma Glutathione and Prodromal Parkinson's Disease Probability [published online ahead of print, 2021 Oct 25]. 28826 Plasma Glutathione and Prodromal Parkinson's Disease Probability [published online ahead of print .
JAMA Neurol: Turning a blind eye—a case report of visual negligence after isolated superior colliculus disease

 Time of Update: 2021-11-13

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Using Singlims for analysis and statistical analysis (Figure 2), comparing the patient's eye movement data with the eye movement data of 15 age- and gender-matched healthy controls (HC) confirmed the hypothesis that the left side is ignored and the gaze is significantly reduced And lower cumulative fixation duration (patient: 5.
Alz Res Therapy: Hereditary dementia, the regional distribution of tau protein is highly correlated with cognitive decline

 Time of Update: 2021-11-13

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Another ADAD study found that tau PET was only elevated in impaired individuals, and suggested that MTL tauopathy, including EC, may be less involved in ADAD compared with sporadic ADLongitudinal PET studies have demonstrated pathological changes in fragile sporadic AD populations, but in ADAD, longitudinal measurements of tau and Aβ PET, and measurements of brain structure and cognitive function have not been reported .
JNER: Clinicians' views on wearable devices that track upper limb activity after stroke: a qualitative focus group study

 Time of Update: 2021-11-13

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The purpose of this study is to understand the views of clinicians for post-stroke upper limb activity tracking wearable device and its potential for use in the rehabilitation practice article published in "Neurology, Neurosurgery and Psychiatry" ( Journal of Neurology, Neurosurgery & Psychiatry ) .
Lancet Psychiatry: Plasma long-chain fatty acids have a protective effect on schizophrenia

 Time of Update: 2021-11-13

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Associations between plasma fatty acid concentrations and schizophrenia: a two-sample Mendelian randomisation study [published online ahead of print, 2021 Nov 1]. Associations between plasma fatty acid concentrations and schizophrenia: a two-sample Mendelian randomisation study [published online ahead of print, 2021 Nov 1].
Alz Res Therapy: Will cognitively normal elderly and high-intensity physical exercise make the brain more agile?

 Time of Update: 2021-11-13

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A recent 12-week elderly intervention study showed that compared with moderate-intensity exercise or stretching controls, high-intensity exercise has a greater improvement in memory . The use of high-intensity exercise in the elderly is safe and provides an effective way to improve physical health.
Stroke: What factors determine the prognosis of disabled patients and thrombectomy treatment after stroke?

 Time of Update: 2021-11-13

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Due to concerns about poor results and potentially useless causes, stroke patients with pre-disability are excluded from randomized clinical trials regardless of the cause of the disability .
Neurology: After a stroke, considering the ischemic penumbra is helpful to predict the patient's prognosis

 Time of Update: 2021-11-13

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The important significance of this study lies in the discovery: considering the functional recovery of hypoperfused tissues with a large infarct core at baseline, the expected benefit of treatment can be more accurately estimated .
Annals of Neurology: Automatic measurement of peak load of epileptiform activities may improve the prognosis of patients with epilepsy

 Time of Update: 2021-11-13

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developed a new automated method that can effectively annotate all epileptiform patterns in a large number of continuous EEG records of acutely ill hospitalized patients . developed a new automated method that can effectively annotate all epileptiform patterns in a large number of continuous EEG records of acutely ill hospitalized patients .
Alzheimers & Dementia: Investigating the relationship between cancer and dementia risk

 Time of Update: 2021-11-13

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found in a large prospective community cohort study that cancer has been determined by several epidemiological studies to have a protective effect on dementia, especially Alzheimer’s disease (AD) .
Environmental Health Perspectives: Air pollution causes brain inflammation and reduces sperm count

 Time of Update: 2021-11-13

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The research team further knocked out IKK2 in specific neurons of healthy mice, and they began to show a decrease in sperm counts when they were exposed to polluted air .
Neurology: cerebral apoplexy, CT hypoperfusion-low-density area, which is conducive to the discovery of stroke patients within 4.5 hours

 Time of Update: 2021-11-13

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5 hours" on patients with acute ischemic stroke, and the time of symptom onset was known . The predictive value of hypoperfusion-low density mismatch in identifying patients with onset of symptoms within 4.
How to maintain brain health after cerebral hemorrhage

 Time of Update: 2021-11-13

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Floris Schreuder and colleagues conducted a prospective, randomized, open-label Phase 2 trial (APACHE-AF) in 16 hospitals in the Netherlands to study the effects of apixaban and antiplatelet drugs after anticoagulation-related cerebral hemorrhage in patients with atrial fibrillation.
Neurology: Zhejiang University: Spinocerebellar ataxia, neurofilament light chain level is closely related to disease severity

 Time of Update: 2021-11-13

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In patients with spinocerebellar ataxia type 3 (SCA3), NfL is higher in CSF and serum, and is related to clinical severity . In SCA2 patients, after adjusting for age, serum NfL levels were correlated with disease severity (SARA, r = 0.
Brain: Plasma Aβ42/40 and phosphorylated-tau217 help predict the pathological prognosis of Alzheimer's disease

 Time of Update: 2021-11-13

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manageOriginal sourcePlasma markers predict changes in amyloid, tau, atrophy and cognition in non-demented subjects, Brain, Volume 144, Issue 9, September 2021, Pages 2826 –2836, https://doi. 1093/brain/awab163Plasma markers predict changes in amyloid, tau, atrophy and cognition in non-demented subjects, Brain, Volume 144, Issue 9, September 2021, Pages 2826 –2836, https://doi.
Neurology: After 20 years of tracking, what is the mortality rate of Parkinson's patients?

 Time of Update: 2021-11-13

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They use data from the National Vital Statistics System, which is a national, population-based death registry to determine trends in PD death rates across the country, in general and by age, gender, race/ethnicity, urban-rural Classification and geographic location .
Enlarged ventricles, not all hydrocephalus, but also these reasons...

 Time of Update: 2021-11-13

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The enlargement of the lateral ventricle caused by general brain atrophy is usually symmetrical, with no shift in the midline . Many kinds of brain development abnormalities can simultaneously manifest the right ventricle enlargement, including forebrain anemia, split brain malformation, anencephaly and giant gyrus .
Nature: Immune cells actually secrete neurotransmitters to limit tumor immunity

 Time of Update: 2021-11-13

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Lack of B cells or specific inactivation of GABA-producing enzyme GAD67 in B cells can enhance anti-tumor responseTherefore, the results of the study show that in addition to cytokines and membrane proteins, small metabolites derived from B cells also have immunomodulatory functions, which may be a pharmaceutical target that allows fine-tuning of the immune response .
The difference between radial crown and semi-oval center

 Time of Update: 2021-11-13

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The center of the semi-oval usually refers to the white matter area above the top of the lateral ventricle, which means that the lateral ventricle is no longer visible when the center of the semi-oval is seen .
10 major contraindications for intravenous thrombolysis, easy to remember with one picture!

 Time of Update: 2021-11-13

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Thrombolytic drugs to promote fibrinolysis and to dissolve blood clots in medicine . Thrombolytic enzymes can act directly or indirectly on all links of the fibrinolytic system . The fibrinolytic system consists of plasminogen, plasmin, activating zymogen and inhibitors .

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Study of Nervous System

Mov Disord: Is it possible to suffer from Parkinson's, check glutathione and take a look

JAMA Neurol: Turning a blind eye—a case report of visual negligence after isolated superior colliculus disease

Alz Res Therapy: Hereditary dementia, the regional distribution of tau protein is highly correlated with cognitive decline

JNER: Clinicians' views on wearable devices that track upper limb activity after stroke: a qualitative focus group study

Lancet Psychiatry: Plasma long-chain fatty acids have a protective effect on schizophrenia

Alz Res Therapy: Will cognitively normal elderly and high-intensity physical exercise make the brain more agile?

Stroke: What factors determine the prognosis of disabled patients and thrombectomy treatment after stroke?

Neurology: After a stroke, considering the ischemic penumbra is helpful to predict the patient's prognosis

Annals of Neurology: Automatic measurement of peak load of epileptiform activities may improve the prognosis of patients with epilepsy

Alzheimers & Dementia: Investigating the relationship between cancer and dementia risk

Environmental Health Perspectives: Air pollution causes brain inflammation and reduces sperm count

Neurology: cerebral apoplexy, CT hypoperfusion-low-density area, which is conducive to the discovery of stroke patients within 4.5 hours

How to maintain brain health after cerebral hemorrhage

Neurology: Zhejiang University: Spinocerebellar ataxia, neurofilament light chain level is closely related to disease severity

Brain: Plasma Aβ42/40 and phosphorylated-tau217 help predict the pathological prognosis of Alzheimer's disease

Neurology: After 20 years of tracking, what is the mortality rate of Parkinson's patients?

Enlarged ventricles, not all hydrocephalus, but also these reasons...

Nature: Immune cells actually secrete neurotransmitters to limit tumor immunity

The difference between radial crown and semi-oval center

10 major contraindications for intravenous thrombolysis, easy to remember with one picture!