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What are the imaging manifestations of brain malformations and developmental disorders?
Time of Update: 2021-11-13
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cn/live/8f733c438eab96Teacher Zhang Junhai's complete course: Click to enter and learn nowTeacher Zhang Junhai's complete course: Click to enter to learn now Click to enter to learn nowDownload the Metz Medical App for a better learning experience .
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Alzheimers & Dementia: The impact of persistence on cognition in multi-domain lifestyle interventions (Finger)
Time of Update: 2021-11-13
The Finnish Study on Elderly Intervention and Prevention of Cognitive Impairment and Disability (Finger) is the first large-scale multi-domain life>.
The Finnish Study on Elderly Intervention and Prevention of Cognitive Impairment and Disability (Finger) is the first large-scale multi-domain life>.
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Eur J Pharm Biopharm: Improving the negative effects of the new Amodafinil microneedle patch on sleep deprivation
Time of Update: 2021-11-13
Amodafinil microneedle can significantly improve the cognitive level of sleep-deficient rats, thereby reducing the various adverse effects of sleep deprivation on mice.
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Lancet Sub-Journal: Mesenchymal stem cells treat multiple sclerosis?
Time of Update: 2021-11-13
Recently, experts from the Department of Neuroscience of the University of Genoa in Italy conducted a MESEMS study to evaluate the safety, tolerability and activity of autologous mesenchymal stem cells derived from bone marrow for the treatment of multiple sclerosis.
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Double 11 celebration!
Time of Update: 2021-11-13
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JNNP: Laser anterior capsulotomy for the treatment of obsessive-compulsive disorder: lesion size and fiber tractography are related to prognosis
Time of Update: 2021-11-13
This retrospective case series includes patients who underwent laser anterior capsulotomy for obsessive-compulsive disorder between 2015 and 2020 .
In short, laser anterior capsulotomy can immediately improve the severity of obsessive-compulsive disorder symptoms .
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JAMA Neurol: In the treatment of cryptogenic stroke with left ventricular insufficiency, which is better, rivaroxaban or aspirin?
Time of Update: 2021-11-13
Myocardial infarction thrombosis Recently, some researchers have hypothesized that anticoagulation is superior to antiplatelet therapy in reducing the risk of cardiac embolism and secondary stroke in ESUS patients, and there is evidence of left ventricular dysfunction .
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JNER: Visual feedback improves the illusion of movement caused by tendon vibration after chronic stroke
Time of Update: 2021-11-13
The purpose of this study is to test whether visual feedback can improve the movement illusion caused by tendon vibration in chronic stroke patients .
Visual feedback improves movement illusions induced by tendon vibration after chronic stroke J NeuroEngineering Rehabil 18, 156 ( 2021).
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JNNP: Long-term neuropsychiatric symptoms in patients with spontaneous cerebral hemorrhage
Time of Update: 2021-11-13
Neuropsychiatric (NP) characteristics according to intracerebral hemorrhage (ICH) subtype and cognitive status Among 560 patients with cerebral hemorrhage, 265 survived at 6 months .
During the 6-month follow-up, the prevalence of apathy and hyperactivity in affective symptoms was associated with a high risk of new-onset dementia (HR 5.
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Alz Res Therapy: Fudan University-Shanghai Research on Aging, renal dysfunction is closely related to dementia
Time of Update: 2021-11-13
In this study, Mengjing Wang and others of Fudan University verified that lower levels of kidney function increase the risk of dementia in the elderly in China .
Kidney function and dementia risk in community-dwelling older adults: the Shanghai Aging Study.
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Neurology: BMI affects the degree of disability of peroneal muscular atrophy
Time of Update: 2021-11-13
investigated the association between body mass index (BMI) and the disability of children with Charcot-Marie-Tooth disease (CMT) .
investigated the association between body mass index (BMI) and the disability of children with Charcot-Marie-Tooth disease (CMT) .
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How to distinguish vascular origin, cytotoxicity, and interstitial cerebral edema?
Time of Update: 2021-11-13
The tumor compresses the surrounding brain tissue or obstructs the cerebral venous return, increases the venous pressure, the absorption of the cerebrospinal fluid circulation mechanism, and the tumor’s biological toxicity, which affects the surrounding brain tissue and blood The brain barrier is damaged or destroyed, the permeability of the blood vessel wall is increased, and localized vasogenic brain edema is produced .
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Brain: TSPO PET helps to monitor and identify progressive multifocal leukoencephalopathy
Time of Update: 2021-11-13
post-IRIS-PMLIn fact, in 3 patients, treatment with rituximab did not affect the uptake of the tracer in the designated PML lesions after Natalizumab-related PML treatment, but multiple sclerosis in the designated active phase Restore the tracer intake to the baseline level in the symptomatic lesions .
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Alz Res Therapy: Genetic variation may reveal the underlying mechanism of AD
Time of Update: 2021-11-13
analyzed the relationship between variants in the top 30 non-APOE AD risk genes and transcript expression levels in the current large-scale GWAS research, as well as brain amyloidosis, tauopathy and The comprehensive analysis of the pathological process of neurodegeneration uses baseline and follow-up data of CSF, PET, and MRI related to AD .
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JAMA Neurol: How effective is the intervention for vascular risk factors in preventing dementia?
Time of Update: 2021-11-13
Recently, in a multi-field intensive vascular care to prevent dementia (PreDIVA) trial, researchers observed that interventions for vascular risk factors in community elderly people for more than 6-8 years did not significantly reduce the risk of dementia .
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JNNP: Early blood pressure reduction after acute cerebral hemorrhage, a systematic review and meta-analysis of individual patient data
Time of Update: 2021-11-13
The included trials involved adults (>18 years of age) with acute primary spontaneous cerebral hemorrhage (<7 days); compared with placebo or concurrent guidelines for blood pressure management, fixed activity using oral, sublingual, transdermal or intravenous administration Drugs or intensive, titrated targeted antihypertensive intervention for random participants, using single or combined therapy; and record clinical and/or radiological results.
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Brain: tau protein is related to the pathological progression, disease stage and memory performance of the medial temporal lobe subregions of AD patients
Time of Update: 2021-11-13
In the later stages, the accumulation of tau protein in the neocortex, temporal lobe and finally the parietal region of the brain becomes abnormalSecond, in individuals with unimpaired cognitive function, the increase in tau load is related to the local atrophy of the entorhinal cortex, Brodmann 35 area and the anterior hippocampus, while the tau load of several medial anterior temporal lobe subregions is related to the posterior hippocampus.
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Nature: What genetic factors affect the nutritional status and development of children?
Time of Update: 2021-11-13
Humans with MC3R loss-of-function mutations, including a rare homologous individual whose puberty starts laterThe sexual maturation of mice lacking Mc3r is delayed, and the length of the reproductive cycle is not sensitive to nutritional interference .
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Alzheimer Dementia: Pathological indicators of Alzheimer's disease, the culprit of dementia
Time of Update: 2021-11-13
In this case, the extent to which AD pathology explains the clinical symptoms and disease progression of living individuals in the AD continuum is indeed of great significance for the development and positioning of effective therapies .
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JAMA Neurol: A lot of physical exercise reduces Parkinson's disease mortality
Time of Update: 2021-11-13
The mortality rate of individuals who started PA after receiving a diagnosis of Parkinson's disease is lower than those who are physically inactive This analysis found a dose-response relationship between PA and Parkinson’s disease all-cause mortality .
