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Epidemiological studies have shown that up to 40% of dementia cases can be attributed to modifiable risk factors
.
However, there is no consistent evidence that multi-domain interventions for these risk factors can prevent or delay dementia
Epidemiological studies have shown that up to 40% of dementia cases can be attributed to modifiable risk factors
The PreDIVA trial included 3526 participants between the ages of 70 and 78 without dementia.
They were recruited from the general population from 2006 to 2009, and 4% of them had a Mini-mental State test score of less than 24.
Points
.
Participants were randomly divided into two groups during 6-8 years.
The PreDIVA trial included 3526 participants between the ages of 70 and 78 without dementia.
During the 4-year observational follow-up, the researchers assessed the dementia status of all participants who survived without dementia during the trial phase .
- During the extended observation period, in addition to the 233 participants who were diagnosed with dementia during the trial phase, 176 participants who were diagnosed with dementia were confirmed (missing rate: 35 [1.
The results of current long-term follow-up studies support the view that multi-domain interventions for vascular risk factors in the real world may not reduce the incidence of Alzheimer’s
The study population may be too old to offset lifelong damage, or the study contrast may not be enough because the quality of daily care in the control group is high
The magnitude of the potential benefits of life> , as the data now shows in older adults
Literature source:https://pubmed.
https://pubmed.
80599.
net/34633434/.
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