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    Home > Active Ingredient News > Study of Nervous System > Neurology: After a stroke, considering the ischemic penumbra is helpful to predict the patient's prognosis

    Neurology: After a stroke, considering the ischemic penumbra is helpful to predict the patient's prognosis

    • Last Update: 2021-11-13
    • Source: Internet
    • Author: User
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    Of the 7 randomized clinical trials that validated mechanical thrombectomy (MT), 4 of them excluded patients with acute ischemic stroke (AIS) caused by anterior great vessel occlusion (LVO) , so it is impossible to treat MT in this sub-subject.


    Thrombotic vascular stroke



    diagnosis

    Participation of the specific penumbra area in the core of the infarction has been shown to have a lot to do with determining the functional outcome, which indicates that patients with a treatable voice area have greater benefits for vascular reconstruction




    manage

    They included a total of 138 baseline LIC patients (MT n=96 or BMM n=42; mean age±SD, 72.


    The average core volume and severely high perfusion volume were 100.


    Taking into account the functional correlation of the infarct position, the model showed better accuracy for the prediction of mRS=0-3.


    The c-Statistic of the logistic regression model and bootstrap-random-forest test set are 0.


    In contrast, in the logistic regression model that does not consider functional recovery, c-Statistic is 0.


    The important significance of this study lies in the discovery: considering the functional recovery of hypoperfused tissues with a large infarct core at baseline, the expected benefit of treatment can be more accurately estimated


    Taking into account the functional recovery of hypoperfused tissues with large infarct cores at baseline, the expected benefit of treatment can be more accurately estimated





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