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JAMA Sub-Journal: How to use anticoagulation and antiplaten in stroke patients caused by embolism?
Time of Update: 2021-12-03
3828Left Ventricular Dysfunction Among Patients With Embolic Stroke of Undetermined Source and the Effect of Rivaroxaban vs Aspirin: A Subgroup Analysis of the NAVIGATE ESUS Randomized Clinical Trial.
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2021 AHA ASCEND: The effect of aspirin on dementia and cognitive impairment
Time of Update: 2021-12-03
To this end, some scholars have explored, aiming to conduct a pre-designated secondary analysis (with longer follow-up time) in the ASCEND study to evaluate the impact of low-dose aspirin on the risk of dementia and cognitive impairment, and conducted a report at the AHA conference Share .
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Alz Res Therapy: Which proteins are in the cerebrospinal fluid and are related to tau-Aβ
Time of Update: 2021-12-03
In this way, Julia Remnestål of the Royal Institute of Technology in Sweden and others explored the association of 104 proteins, which are known to be enriched in the brain or related to different types of neurodegenerative diseases, and are related to the AD pathological evidence of CSF biomarkers.
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JAMA Neurology: Comparison of 8 plasma amyloid Aβ42/40 detection methods in patients with Alzheimer's disease
Time of Update: 2021-12-03
Immune coupled mass spectrometry (IP-MS) - Immunoprecipitation precision precision immunoprecipitation - coupled mass spectrometry (IP-MS) Diagnosis Recently, the same group of researchers early AD patients in Sweden conducted studies BIOFINDER 8 kinds of method for detecting Aβ One by one comparison to evaluate the ability to distinguish between plasma Aβ42/40 measured by different methods and normal cerebrospinal fluid Aβ42/40 or Aβ-PET status .
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Am J Psychiatry prevention and treatment of substance use disorders can reduce mortality in patients with eating disorders
Time of Update: 2021-12-03
The hazard ratio was calculated to compare the risk of all-cause death between patients with eating disorders and the control group (including with and without lifelong SUD diagnosis (abuse or dependence on alcohol, marijuana, or hard drugs)) .
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Stroke: Blood pressure change trajectory and patient outcome after intravascular thrombectomy
Time of Update: 2021-12-03
Recently, a research article was published in Stroke, an authoritative journal in the field of cardiovascular diseases, which aims to identify subgroups of patients with different blood pressure trajectories after EVT, and to study their association with imaging results and functional outcomes .
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IEEE trans: Quantitative assessment of upper limb motor function in post-stroke rehabilitation based on motion synergy analysis and multimodal fusion
Time of Update: 2021-12-03
Considering that the evaluation system can identify pathological movements with a high degree of accuracy, it is further explored whether this method can quantitatively analyze the upper extremity movement injuries of patients with hemiplegia after stroke .
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Am J Psychiatry: Neurocognitive features can predict susceptibility and resilience to post-traumatic stress
Time of Update: 2021-12-03
Threat enhancement and slow reward response may reflect stress vulnerability, clusters that show high responses to both threats and rewards, and the highest level of neuroimaging phenotypes that appear in the early post-traumatic period and the risk or resilience of trauma-related psychopathology Related .
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Stroke: One-year outcome of patients with acute basilar artery occlusion after endovascular treatment
Time of Update: 2021-12-03
The beneficial effect of endovascular treatment on the 1-year functional outcome of patients with acute basilar artery occlusion is similar to the 90-day outcome reported in the original study .
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JAMA Neuro: In stroke with extended time window of aortic occlusion, which one is CT, CTP or MRI?
Time of Update: 2021-12-03
In order to further compare the clinical results of mechanical thrombectomy patients selected by non-enhanced CT, CTP or MRI in the extended time window, experts from the Department of Neurology of Boston University School of Medicine conducted related research, and the results were published in the journal JAMA Neurology .
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Alz Res Therapy: Neurofilament light chain and p-tau 181 can predict the progression of dementia
Time of Update: 2021-12-03
In this way, Christopher Clark and others of the University of Zurich explored the ability of plasma NfL and plasma p-tau181 levels or their combination as blood biomarkers for diagnosing brain AD pathology and predicting clinical disease progression .
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Alz Res Therapy: 27-Hydroxycholesterol is closely related to cognitive decline
Time of Update: 2021-12-03
cholesterolIn epidemiological studies, elevated circulating cholesterol, especially in middle age, is associated with an increased risk of dementia and AD, through vascular- related pathways (such as atherosclerosis, stroke, and/or decreased cerebral blood flow) or with the brain Potential link to amyloid deposition .
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Stroke: Increased COVID-19 mortality in patients with past cerebrovascular diseases
Time of Update: 2021-12-03
Heart vascular stroke COVID-19This prospective population-based cohort study included all COVID-19 positive cases from February 1 to July 31, 2020 .
Past strokes are associated with higher mortality in people under 80 years of age .
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Beijing Xuanwu Hospital: Alzheimer's disease has a marker?
Time of Update: 2021-12-03
In a study where the AD group and the control group were about the same age, the sensitivity analysis results of CSF sTREM2 level and AD risk .
775432Age Matching Is Essential for the Study of Cerebrospinal Fluid sTREM2 Levels and Alzheimer's Disease Risk: A Meta-Analysis.
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Guide and standardize the treatment of vascular cognitive impairment
Time of Update: 2021-12-03
(1) Anti-dementia drugs, including cholinesterase inhibitors and NMDA receptor antagonists, are first used for the drug treatment of BPSD in VaD patients, which may improve the cognitive function impairment of VaD patients as well as their mental and behavioral symptoms .
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Stroke: Long-term cognitive decline after stroke
Time of Update: 2021-12-03
A meta-analysis of individual participant data is used to assess the rate of change in cognitive function and risk factors for cognitive decline after stroke .
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Neurology: Reproductive history affects middle-aged dementia risk
Time of Update: 2021-12-03
More estrogen exposure events in the reproductive history, such as premenopausal status, longer reproductive span, more children, use of HT and HC, are associated with greater GMV in middle-aged women .
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Nature: Acupuncture is no longer "metaphysics"!
Time of Update: 2021-12-03
For the traditional technique of acupuncture and moxibustion, the use of modern science and technology to strongly prove its effectiveness and unique advantages in disease treatment is an affirmation of acupuncture and has trans-age significance .
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Stroke: Effects of Cilostazol and Aspirin on White Matter Changes in Cerebral Small Vessel Diseases
Time of Update: 2021-12-03
Blood vesselRecently, a research article was published in Stroke, an authoritative journal in the field of cardiovascular diseases, which aims to compare the effects of cilostazol and aspirin on the changes of WMC volume in patients with cerebral small vessel disease .
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Mov. Disord: APOE ε4 affects the progression of Parkinson's disease
Time of Update: 2021-12-03
Disord and analyzed whether APOE ε4 contributes to the progression of early Parkinson's disease (PD) .
Disord and analyzed whether APOE ε4 contributes to the progression of early Parkinson's disease (PD) .