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Acute basilar artery occlusion (BAO) is a potentially catastrophic disease, accounting for 1% of all ischemic strokes and 5% of large vessel occlusive (LVO) strokes
.
Although several large RCT trials since 2015 have confirmed the safety and effectiveness of thrombectomy in acute ischemic stroke caused by anterior circulation and large vessel occlusion
Stroke blood vessel
Recently, a research article was published in Stroke, an authoritative journal in the field of cardiovascular diseases.
Researchers jointly carried out a multi-center clinical registration study for endovascular treatment of acute basilar artery occlusion (the EVT for Acute Basilar Artery Occlusion Study) in 47 hospitals in China.
, BASILAR), this study is a national prospective non-randomized study that included patients with acute basilar artery occlusion who received endovascular treatment or conventional treatment from January 2014 to May 2019
.
The purpose of this study is to report the outcome of one-year clinical follow-up of these patients
Cardiovascular
The main outcome of the study was the modified Rankin scale at one year.
The researchers used ordinal logistic regression analysis to estimate the general odds ratio and adjusted it according to pre-specified prognostic factors
.
Secondary outcomes included the outcome grouping based on the modified Rankin scale (0-1, 0-2, or 0-3) and all-cause death at one year
Among the 829 patients initially registered with BASILAR, 785 patients (94.
7%) were followed up for one year
.
The result distribution of the modified Rankin scale favors endovascular treatment rather than conventional treatment (adjusted general odds ratio is 4.
It can be seen that the beneficial effect of endovascular treatment on the 1-year functional outcome of patients with acute basilar artery occlusion is similar to the 90-day outcome reported in the original study
.
.
Original source:
Original source:Fengli Li.