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Stroke: Effects of Cilostazol and Aspirin on White Matter Changes in Cerebral Small Vessel Diseases

 Last Update: 2021-12-03
 Source: Internet
 Author: User

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Cerebral small vessel wherein the disease is a progressive change in the white matter (the WMC)
.

Blood vessel

Recently, a research article was published in Stroke, an authoritative journal in the field of cardiovascular diseases, which aims to compare the effects of cilostazol and aspirin on the changes of WMC volume in patients with cerebral small vessel disease
.

Cardiovascular

In this multi-center, double-blind, randomized controlled trial, participants with moderate or severe WMC and at least one lacunar infarction detected on a brain magnetic resonance imaging examination were randomly assigned to the West at a 1:1 ratio.
Lostazol group and aspirin group
.

The subjects took cilostazol sustained-release capsules (200 mg) or aspirin (100 mg) capsules once a day for 2 years

Stroke

Between July 2013 and August 2016, 256 participants were randomly assigned to the cilostazol (n=127) group and aspirin (n=129) group
.

Over the past two years, the percentage of WMC volume in the total WM volume and the percentage of WMC volume in the intracranial volume of the two groups of subjects have both increased, but neither analysis showed a significant difference between the groups

It can be seen that there is no significant difference in the effects of cilostazol and aspirin on the progression of WMC in patients with cerebral small vessel disease
.

There was no significant difference in the effects of cilostazol and aspirin on the progression of WMC in patients with cerebral small vessel disease
.

Original source:

Byeong C.

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