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    Home > Active Ingredient News > Study of Nervous System > Am J Psychiatry: Neurocognitive features can predict susceptibility and resilience to post-traumatic stress

    Am J Psychiatry: Neurocognitive features can predict susceptibility and resilience to post-traumatic stress

    • Last Update: 2021-12-03
    • Source: Internet
    • Author: User
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    The neural model of stress vulnerability involves overreaction in areas involved in threat detection and fear response, such as the amygdala, insula, and dorsal cingulate cortex (dACC)


    prevention

    Jennifer S.


    Jennifer S.


    The study collected functional MRI (fMRI) scans of civilian trauma survivors in different areas 2 weeks after the trauma


    In further research on post-traumatic recovery, functional MRI scans of trauma survivors in threat, suppression, and reward tasks

    In further research on post-traumatic recovery, functional MRI scans of trauma survivors in threat, suppression, and reward tasks

    Participants reported psychopathological symptoms in the first 6 months after trauma through a mobile survey


    In the discovery group (N=69) and the replication group (N=77), functional MRI (fMRI) of trauma survivors showed four clusters


    In the discovery group (N=69) and the replication group (N=77), functional MRI (fMRI) of trauma survivors showed four clusters


    Two weeks after a motor vehicle collision, task-based functional MRI identified 4 groups of individuals based on neural activity characteristics reflecting threat response, reward response, and inhibitory participation


    When trauma survivors perform threats, rewards, and suppression tasks, the whole brains of the four groups are compared

    When trauma survivors perform threats, rewards, and suppression tasks, the whole brains of the four groups are compared

     The neuroimaging phenotype that appears early after trauma is related to the risk or resilience of trauma-related psychopathology


    The neuroimaging phenotype that appears early after trauma is related to the risk or resilience of trauma-related psychopathology


    Original source

    Brain-Based Biotypes of Psychiatric Vulnerability in the Acute Aftermath of Trauma.


    Brain-Based Biotypes of Psychiatric Vulnerability in the Acute Aftermath of Trauma.


    https://ajp.
    psychiatryonline.
    org/doi/full/10.
    1176/appi.
    ajp.
    2021.
    20101526

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