-
Can't sleep well or not enough?
Time of Update: 2021-11-04
Only for medical professionals to read and refer to clinical information, 1s to reach more cutting-edge clinical information, pay attention to clinical assistants in the medical community Reliable, but it does not make any promises or guarantees on the timeliness of the published content, and the accuracy and completeness of the cited information (if any), and does not assume that the content is outdated and the cited information may be inaccurate.
-
Studying while sleeping!
Time of Update: 2021-11-03
▲The paper was published in the "Current Biology" magazine (picture source: screenshot of the paper page) The hippocampus located in the medial temporal lobe (MTL) plays an important role in brain learning and is indispensable for the formation and storage of memories Part .
-
The team of Professor Eveline Barbieri of Baylor College of Medicine in the United States AS: CHAF1A blocks neuronal differentiation through metabolic reprogramming and promotes the occurrence of neuroblastoma
Time of Update: 2021-11-03
Recently, the team of Professor Eveline Barbieri of Baylor College of Medicine in the United States found that chromatin assembly factor 1A (CHAF1A) regulates the development, proliferation, differentiation, and expression of metabolic-related genes, thereby limiting zebrafish neural crest cells and human nerves.
-
Astrocyte Ca2+ induces ATP release to regulate myelin axon excitability and conduction velocity
Time of Update: 2021-11-03
Using the quinacrine labeling method, the author observed that ATP-containing vesicles in astrocyte are distributed around the myelinated axons of layer V pyramidal neurons, and the release of Ca2+ in the astrocytes will cause the vesicles Decrease in the number (43%) (Figure 1 GI).
Figure 6A-I Increased Ca2+ concentration in astrocytes regulates pyramidal cell excitability and axonal conduction velocity (Source: J.
-
Lancet Neurol: Diagnosis and prognostic performance and longitudinal changes of plasma neurofilament light chain concentration in adults with Down syndrome
Time of Update: 2021-11-02
The plasma NfL concentration of the asymptomatic non-progressive group showed an annual increase of 3.
The plasma NfL concentration of the asymptomatic non-progressive group showed an annual increase of 3.
The plasma NfL concentration of the asymptomatic non-progressive group showed an annual increase of 3.
-
Brain: The early stages of tau protein and its relationship with brain function connection, atrophy and memory
Time of Update: 2021-11-02
Abnormal sequence of biomarkers in non-dementia elderlyIn addition, the reduction of tau-related functional connections in the key network between the medial temporal lobe and the mid-posterior system area is related to this early memory impairment .
-
Lancet Neurol: Comparison of CSF biomarkers for Down syndrome and autosomal dominant Alzheimer's disease
Time of Update: 2021-11-02
The pattern of Alzheimer’s disease-related CSF biomarkers in Down syndrome patients is very similar to that of autosomal dominant Alzheimer’s disease mutation carriers , including a reduced ratio of Aβ1-42 to Aβ1-40 (all p<0· 0080) and the increase of phosphorylated tau markers-related processes; neuron, axon and synapse damage (p<0·080); astrocyte hyperplasia and neuroinflammation, and the degree of abnormality is higher in patients with dementia .
-
JPD: Patients with Parkinson's disease have impaired response inhibitory function during walking
Time of Update: 2021-11-02
They performed visual Go/NoGo tasks on 30 Parkinson's disease patients, 30 elderly and 11 young adults while sitting and walking on a treadmill, and recorded their brain electrical activity and gait at the same time .
-
JPD: Does smoking and drinking increase the risk of Parkinson's?
Time of Update: 2021-11-02
Mendelian Randomisation Study of Smoking, Alcohol, and Coffee Drinking in Relation to Parkinson's Disease.
3233/JPD-212851 Mendelian Randomisation Study of Smoking, Alcohol, and Coffee Drinking in Relation to Parkinson's Disease.
-
JNER: Neuromuscular stimulation assisted strategy for remote self-rehabilitation of upper limbs at home after stroke
Time of Update: 2021-11-02
The results show that with the assistance of WH-ENMS driven by electromyography, a home-based remote self-help rehabilitation program is feasible and effective for improving the motor function of upper limbs after stroke .
-
Lancet Neurol: From 1990 to 2019, a review of the global burden of stroke and risk factors in the past 30 years
Time of Update: 2021-11-02
High blood pressure, elevated blood lipids, diabetes (high fasting blood sugar), smoking, low physical activity, unhealthy diet, and abdominal obesity (high body mass index) diabetes Recently, researchers have estimated the burden of stroke, ischemic stroke, cerebral hemorrhage and subarachnoid hemorrhage globally, regionally and nationally, as well as stroke-related DALY and 19 potentially changeable behaviors, environments, and occupations.
-
JPD: Multi-dimensional assessment tool to help assess the quality of life of Parkinson's patients
Time of Update: 2021-11-02
Development of a Multidimensional Assessment Tool for the Evaluation of Holistic Quality of Life in Parkinson's Disease.
3233 /JPD-202391 Development of a Multidimensional Assessment Tool for the Evaluation of Holistic Quality of Life in Parkinson's Disease.
-
JPD: Parkinson's patients, small subcortical volume, or suggest gait disorder
Time of Update: 2021-11-02
To our knowledge, previous studies did not use instrumental measurements of balance and gait to examine specific aspects of mobility related to ventricular expansion or global and regional cortical and subcortical volume atrophy in 65 PD patients .
-
JPD: Parkinson's patients often fall and the possibility of hospitalization is greatly increased
Time of Update: 2021-11-02
We explored (1) the frequency and causes of acute hospitalization of PD patients in the Spanish cohort, followed up for 1 year; (2) determined the predictors of acute hospitalization .
-
IJNS: Empower people with dementia
Time of Update: 2021-11-02
An article published in the International Journal of Nursing Studies explores the concept and process of empowerment of people with dementia, and combines this knowledge with the themes in a conceptual framework based on the views of stakeholders to develop support for empowering people with dementia Lay the foundation for interventions .
-
JNER: Using a treadmill to evaluate the function of spasticity in children with cerebral palsy
Time of Update: 2021-11-02
The purpose of this study is to analyze whether the treadmill disturbance program can energize the calf muscle stretching reflex in children with cerebral palsy and a typical developmental control group .
-
Neurology: For Parkinson's patients, if they are accompanied by rapid eye movement sleep, deep brain stimulation does not affect their prognosis
Time of Update: 2021-11-02
Among 215 PD patients who were followed up for 12 months after STN-DBS, they compared the motor, cognitive, psychological and behavioral characteristics and life of patients with (preoperative RBD+) or without possible RBD (preoperative RBD-) before surgery Quality results .
-
IJNS: Family caregivers participate in the care plan for patients with dementia
Time of Update: 2021-11-02
Petra EM Tasseron-Dries, Hanneke JA Smaling, et al Family involvement in the Namaste care family program for dementia: A qualitative study on experiences of family, nursing home staff, and volunteers , International Journal of Nursing Studies, 2021,https:// doi.
-
How to identify cerebral edema (vascular origin, cytotoxicity, interstitial) in clinical notes?
Time of Update: 2021-11-02
4 In patients with acute cerebral infarction, DWI showed that the left frontal lobe has obvious flaky high signal, and the responsible blood vessel is the frontal branch of the left middle cerebral arteryFig.
-
JPD: Intracranial ultrasound therapy can significantly change the symptoms of Parkinson's tremor
Time of Update: 2021-11-02
The important significance of this study lies in the findings: Unilateral FUS VIM-thalamotomy surgery for TDPD patients is effective and safe, and provides long-term tremor relief for most patients .
Focused Ultrasound Thalamotomy in Tremor Dominant Parkinson's Disease: Long-Term Results.
3233/JPD-212810 Focused Ultrasound Thalamotomy in Tremor Dominant Parkinson's Disease: Long-Term Results.
