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JNER: Observation of motor deficits after stroke: a detailed analysis of the lower limb motor coordination test (LEMOCOT)
Time of Update: 2021-11-13
This article focuses on quantifying the performance error (ie accuracy) in the Lower Extremity Motor Coordination Test (LEMOCOT) for stroke patients (PwS) .
This article focuses on quantifying the performance error (ie accuracy) in the Lower Extremity Motor Coordination Test (LEMOCOT) for stroke patients (PwS) .
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Neurology: Use anticoagulant therapy with caution in patients with unruptured posterior circulation aneurysm in acute ischemic stroke
Time of Update: 2021-11-13
published a research article in Neurology to evaluate whether IVT treatment of AIS can cause UIA rupture and intracranial hemorrhage (ICHs) in patients with unruptured UIA .
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Brain: Pathological severity of AD covariation and potential genetics affect AD grouping and treatment
Time of Update: 2021-11-13
APOE sites are closely related to the risk of Alzheimer's disease and Lewy body (DLB) dementia .
Original source:Genetic evaluation of dementia with Lewy bodies implicates distinct disease subgroups, Brain, 2021;, awab402, https://doi.
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Neurology: GGC repeat amplification of NOTCH2NLC gene in patients with hereditary neuropathy in Taiwan
Time of Update: 2021-11-13
Two of the seven patients have a family history of NIID NOTCH2NLC GGC repeat expansion is an important underestimated cause of hereditary neuropathy .
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Neurology: Trends in U.S. Parkinson's Disease Mortality from 1999 to 2019
Time of Update: 2021-11-13
The researchers used data from the National Vital Statistics System, a nationwide, population-based death registration system to determine the overall rate of Parkinson’s disease mortality and by age, gender, and race.
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Alzheimer Dementia: Plasma exchange and albumin significantly improve the memory and quality of life of patients with Alzheimer's disease!
Time of Update: 2021-11-13
immunityThe results showed that at the 14th month, the language fluency and processing speed of PE-treated mild AD patients were improved compared with placebo (the effect size: >100%; P value: 0.
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An important breakthrough in Parkinson's disease research!
Time of Update: 2021-11-13
Studies in the past few decades have pointed out that in the brains of patients with Parkinson’s disease, dopamine-releasing neurons are constantly lost, leading to the destruction of the motor function regulated by these nerve cells, resulting in slowness, stiffness, uncontrollable tremor and other movement disorders Symptoms .
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iScience: Fat cells play a central role in cognitive decline and neurodegenerative diseases
Time of Update: 2021-11-13
Role of Adipocyte Na, K-ATPase Oxidant Amplification Loop in Cognitive Decline and NeurodegenerationThe study showed that fat cells control the systemic response to brain function, leading to impaired memory and cognitive abilities in mice .
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Neurology: Whether the postoperative effect of epilepsy is good or not depends on the location of the operation
Time of Update: 2021-11-13
0000000000013033 Association Between Anatomical Location of Surgically Induced Lesions and Postoperative Seizure Outcome in Temporal Lobe Epilepsy .
0000000000013033 Association Between Anatomical Location of Surgically Induced Lesions and Postoperative Seizure Outcome in Temporal Lobe Epilepsy .
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Stroke: high-density lipoprotein component, or can increase vascular brain damage
Time of Update: 2021-11-13
In contrast, studies on plasma high-density lipoprotein cholesterol and clinically defined stroke risk usually find a weak association with coronary heart disease, and the results of the study are also inconsistent .
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Neurology: a good lifestyle, or reduce the risk of Parkinson's
Time of Update: 2021-11-13
Alcohol consumption and regular physical activity are associated with a reduced incidence of Parkinson’s disease , but male alcohol consumption (≤3 times a week, OR=0.
Drinking alcohol and regular physical activity are associated with a reduced incidence of Parkinson's diseaseParticipants who had regular health check-ups showed a consistent relationship between life> .
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Aging Cell: Dietary supplementation of citrate can promote longevity
Time of Update: 2021-11-13
Citrate supplementation in the diet may prove to be a useful intervention for the treatment of age-related dysfunction in the future Original source:Original source:Shou-Zen Fan et al.
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Alz Res Therapy: Cholinesterase inhibitor use, or has nothing to do with changes in cognitive function
Time of Update: 2021-11-13
The important significance of this study is that it found that in patients with or without amyloid burden, the use or non-use of CEI has nothing to do with the cognitive changes during the 1-year follow-up .
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Alz Res Therapy: A new MRI method that helps distinguish Alzheimer's disease from frontotemporal dementia
Time of Update: 2021-11-13
In this study, the data came from three different databases, including 47 FTD patients, 47 AD patients, and 47 normal controls in the NACC database; 50 AD patients in the ADNI database; and 50 AD patients in the FTLDNI database.
The MRI images of all subjects were automatically segmented, and AccuBrain® was used to quantify brain atrophy, including AD-RAI .
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Alz Res Therapy: Patients with dementia have lower blood and urine serotonin
Time of Update: 2021-11-13
Because of the link between AD pathogenesis, systemic inflammation, and serotonin signaling, these two pathways have been investigated in the disease before, and it has been reported that compared with the control group, these two pathways have been clinically diagnosed in individuals with AD There is a change in the concentration of circulating metabolites in the pathway .
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More than 60 PPT to get the prevention and treatment of intravenous thrombolysis complications!
Time of Update: 2021-11-13
Intravenous thrombolysis for acute ischemic cerebral stroke , is the most effective way of treatment, but complications caused by intravenous thrombolysis can not be ignored, which transformed cerebral hemorrhage, vascular after re-occlusion, thrombolytic brain edema is intravenous thrombolysis Common complications.
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Neurology: Explore 100,000 people, what is the disease burden of epilepsy?
Time of Update: 2021-11-13
This study showed a high incidence of mental and physical conditions and identified racial and ethnic differences that affect patients with epilepsy .
This study showed a high incidence of mental and physical conditions and identified racial and ethnic differences that affect patients with epilepsy .
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Stroke: After thrombolytic therapy, manage systolic blood pressure, which is conducive to prognosis
Time of Update: 2021-11-13
Therefore, Xia Wang and others of the University of New South Wales conducted a post-hoc analysis (post-hoc) of the completed ENCHANTED data set, including the combined alteplase dose 6 and blood pressure group to determine the summary measures-1 The relationship between the (mean) and variability (SD) reached within 24 hours, and the decline within 1 hour of early SBP control, is associated with key clinical outcomes .
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[Dry goods collection] Precautions and contraindications of top 10 commonly used drugs in neurology
Time of Update: 2021-11-13
1) Like other antiplatelet drugs, patients who are at increased risk of bleeding due to trauma, surgery or other pathological conditions and receive aspirin, NSAIDS including Cox-2 inhibitors, heparin, platelet glycoprotein Ⅱb/Ⅲa (GPⅡb/Ⅲa) Clopidogrel should be used with caution in patients treated with antagonists .
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JMRI: The coexistence of hypertension and cerebrovascular disease is related to the existence of WMH
Time of Update: 2021-11-13
The link between morphological changes of cerebral blood vessels and WMH is supported by a study in young people, which showed that WMH lesion count (WMHC) is related to cerebral blood vessel density .
