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Aging Cell: Dietary supplementation of citrate can promote longevity
Time of Update: 2021-11-13
Citrate supplementation in the diet may prove to be a useful intervention for the treatment of age-related dysfunction in the future Original source:Original source:Shou-Zen Fan et al.
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Neurology: Clinical trials of cerebral apoplexy, the number of female patients included is too small
Time of Update: 2021-11-13
In an analysis of the personal data of more than 19,000 patients from randomized controlled trials of acute stroke , men had a higher mortality rate, while women suffered a greater loss of health-related quality of life .
Stroke Another systematic review of patient-reported results showed that women experience more participation restrictions or barriers than men .
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Alz Res Therapy: Changes in brain function networks may predict cognitive decline in advance
Time of Update: 2021-11-13
This study shows that the new neural features of fMRI-based cognitive decline come from the repeated and concurrent patterns of dfALFF and DFC , providing strong evidence to support SCD as a transitional stage between normal aging and MCI .
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JNNP: Long-term follow-up comparison between acute functional pseudo-stroke and mild acute ischemic stroke
Time of Update: 2021-11-13
Compared with patients with mild AIS, the self-evaluated long-term prognosis of FSM patients is worse .
Compared with patients with mild AIS, the self-evaluated long-term prognosis of FSM patients is worse .
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Stroke: The relationship between hypotension, comorbidities and ischemic stroke mortality
Time of Update: 2021-11-13
The researchers followed up the main outcomes of all-cause mortality and cardiovascular mortality of patients for up to 12 years, and used the Cox model to correlate pre-stroke blood pressure indicators with mortality, and through existing comorbidities (smoking, myocardial Infarction , heart failure, atrial fibrillation/flutter, cancer, and dementia), race, and ethnicity were stratified .
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Mov Disord: Spinocerebellar ataxia type 3 severity is related to lifestyle
Time of Update: 2021-11-13
The study collected data on smoking, drinking, physical activity, physical therapy, and body mass index (BMI) of 243 SCA3 patients and 119 control groups to detect their correlation with age of onset, disease severity, and progression .
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Alzheimers & Dementia: Concussion makes people stupid?
Time of Update: 2021-11-13
Among rugby league players, there is currently little evidence of the long-term effects of concussions on cognition .
Recently, researchers have evaluated the relationship between self-reported concussions and cognitive function of retired rugby players .
The relationship between self-reported concussions and cognitive function of retired rugby players was evaluated.
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It is not difficult to read and understand the guidelines for the emergency diagnosis and treatment of vertigo in 3 minutes!
Time of Update: 2021-11-12
, often accompanied by nausea, vomiting, and often sudden onset with obvious fear, and they go to the emergency department Symptoms and classification of vertigoVertigo Symptoms and Classification In 2009, the Bárány Association Classification Committee (CCBS) divided vestibular disease symptoms into four categories: vertigo, dizziness, vestibular visual symptoms and postural symptoms (see Table 1) .
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Improve these 11 risk factors and prevent stroke World Stroke Day
Time of Update: 2021-11-12
May intervene in risk factors are the main contents of primary prevention of stroke, including high blood pressure, abnormal glucose metabolism, dyslipidemia, heart disease, asymptomatic carotid atherosclerosis, migraine, sleep-disordered breathing, the same type of high-cysteine Acidemia and life>.
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Annals of Neurology: Potential therapeutic targets for Alzheimer's disease: posteromedial and anterior temporal networks
Time of Update: 2021-11-12
Compared with healthy elderly controls, the cross-sectional changes in the functional connections of the medial temporal lobe (MTL) subregions in Alzheimer's disease patients .
Compared with healthy elderly controls, the cross-sectional changes in the functional connections of the medial temporal lobe (MTL) subregions in Alzheimer's disease patients .
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Mov Disord: Parkinson's disease, ApoE may lead to the progression of dyskinesia
Time of Update: 2021-11-12
However, the relationship between lipoprotein E (APOE) ε4 and the movement progression of patients with Parkinson's disease is still unknown .
Apolipoprotein E Genotype Contributes to Motor Progression in Parkinson's Disease .
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Annals of Neurology: The blood-brain barrier is destroyed, and the risk of AD and vascular disease is high
Time of Update: 2021-11-12
In vivo studies have also shown that compared with healthy controls, the cerebrospinal fluid (CSF) of patients with cognitive impairment has a higher blood-borne albumin concentration, indicating BBB destruction .
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Neurology: Proteomics discovery of non-invasive biomarkers related to sports concussion
Time of Update: 2021-11-12
In the end, insulin-like growth factor 1 (IGF-1) and IGF binding protein 5 (IGBFP5) were identified as the most promising non-invasive urine markers for exercise concussion .
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JNNP: Thinning of the outer layer of retinal astrocytes is not a feature of AQP4 IgG seropositive neuromyelitis optica spectrum disorder
Time of Update: 2021-11-12
This article was published in the Journal of Neurology, Neurosurgery & Psychiatry ( Journal of Neurology, Neurosurgery & Psychiatry )In this study, compared with healthy controls (HCs), patients with AQP4 IgG seropositive and MOGAD patients as disease controls were investigated whether ORL thinning occurred, especially in the fovea and macular ONL .
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ANB: Is it useful to stay up late to make up for sleep?
Time of Update: 2021-11-12
Among them, the impact of lack of sleep on negative emotion and physical symptoms is most obvious in 3 consecutive days.
Among them, the impact of lack of sleep on negative emotion and physical symptoms is most obvious in 3 consecutive days.
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Stroke: Five-year follow-up: the natural development of cerebral cavernous deformity
Time of Update: 2021-11-12
It is worth noting that pediatric trials investigating the natural course of the disease and risk factors leading to ICH are very rare, and are usually limited to small patient cohorts, heterogeneous samples, and short follow-up periods .
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Neurology: A systematic review of single-patient crossover trials in neurological research
Time of Update: 2021-11-12
15; range 0-5) were found as the method of quality and reporting Academic measurement standards The N-of-1 test has been reported in many neurological diseases, not only in chronic stable diseases, but also in progressive or acute diseases with stable symptoms .
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Neurology: Qilu Hospital: A case of migratory Roland encephalopathy caused by mitochondrial ND3 mutation
Time of Update: 2021-11-12
10191T>C mutation: Rolandic epilepsy (RE) or childhood benign epilepsy with central temporal spikes (BECT) is the most common idiopathic partial epilepsy syndrome in children, where "idiopathic" means genetic predisposition .
NGS analysis of urine sediment mtDNA showed that the mt-ND3 gene has a pathogenic m.
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Lancet Neurol: Nothing to do with nothing-a study on the safety, tolerability and activity of mesenchymal stem cells and placebo in the treatment of multiple sclerosis (MESEMS)
Time of Update: 2021-11-12
Recently, researchers evaluated the safety, tolerability and activity of intravenous infusion of autologous bone marrow mesenchymal stem cells in patients with active multiple sclerosis .
Recently, researchers evaluated the safety, tolerability and activity of intravenous infusion of autologous bone marrow mesenchymal stem cells in patients with active multiple sclerosis .
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JNER: Robot-assisted evaluation of hand proprioception, motor and sensory impairments after stroke
Time of Update: 2021-11-12
Clinical feasibility (duration), reliability (within-class correlation coefficient ICC , minimum actual difference SRD ) and validity ( Kruskal-Wallis test, Spearman correlation coefficient ρ and Fugl-Meyer upper limb movement assessment, kinesthetic upper and lower test, box Test)Robotic task assessment was performedon 36 subjects with subacute stroke and 31 age-matched neurological intact controls.
