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Stroke: The complication rate of thrombectomy should not be ignored
Time of Update: 2021-11-12
Thrombectomy is a very effective method for the treatment of acute ischemic stroke in the anterior circulation caused by occlusion of large vessels , and more and more eligible patients .
And systematically collected surgical data, embolism complications, perforation and dissection incidence, 90-day clinical results, and bleeding complications .
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Neurology: Incidence, prevalence, longitudinal injury and disability of small fiber neuropathy
Time of Update: 2021-11-12
Recently, studies have evaluated the incidence and prevalence of SFN patients without large fiber involvement (simple) at onset, and longitudinally evaluated patients’ comorbidities, cumulative neurological damage (physical and autonomous), and disability from the perspective of the population.
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JAMA Neurol: Tau-PET can predict preclinical and prodromal prognosis of AD
Time of Update: 2021-11-12
conducted a multicenter longitudinal study to examine the prognostic value of [18F]flortaucipir and [18F]RO948 tau PET in 1431 patients with AD dementia, mild cognitive impairment (MCI) or normal cognition; PET was compared with established MRI and Aβ-PET markers to predict future cognitive changes; and whether age, gender, and Apoe genotype changed over time were associated with baseline Tau-PET and cognitive changes .
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Neurology: Observational Study on the Effect of Levetiracetam Use Time on the Overall Survival Rate of Adult Isocitrate Dehydrogenase Wild-type Glioblastoma
Time of Update: 2021-11-12
Recently, a study investigated whether the use of levetiracetam during the standard combined chemotherapy and radiotherapy regimen and the combined application of temozolomide and whether the duration of levetiracetam (continuous, partial time, or never) affects adult IDH-wild-type glue The overall survival rate in a homogenous single-institution cohort of plasmoblastoma and controls the methylation status of the MGMT promoter .
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Neurology: The performance of McDonald criteria revised in 2017 and 2010 in predicting MS diagnosis after clinically isolated syndrome
Time of Update: 2021-11-12
In addition, in patients with CIS who meet the DIS criteria, the presence of cerebrospinal fluid-specific oligoclonal bands (OCB) can be diagnosed as MS without clinical or magnetic resonance evidence of DIT (from Dryad: Table e-1 https:// doi.
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NEJM Stroke Day: The CHANCE-2 study of Wang Yongjun's team in the Temple of Heaven opens a new era of stroke prevention!
Time of Update: 2021-11-12
Previous CHANCE and POINT studies have suggested that the combined antiplatelet therapy of aspirin and clopidogrel can significantly reduce the 3-month ischemic event risk in patients with high-risk non-disabling ischemic cerebrovascular events .
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Neurology: Can the postgraduates of neurology deal with acute ischemic stroke satisfactorily under the simulation test?
Time of Update: 2021-11-12
In this prospective, observational, single-center simulation-based study, participants (from interns to attending physicians) managed an acute ischemic stroke patient, who subsequently caused tPA-related hemorrhagic transformation leading to brain herniation.
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Neurology: The relationship between neurofilament light chain (NFL) levels and severity of disease in patients with spinocerebellar ataxia type 2
Time of Update: 2021-11-12
Researchers have reported that patients with spinocerebellar ataxia type 3 (SCA3) have higher levels of NFL in cerebrospinal fluid and serum, which are correlated with clinical severity .
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FDA awarded NT102 the title of orphan drug for the treatment of Dravet syndrome
Time of Update: 2021-11-12
FDA NT102 has a wide range of seizure protection in a variety of preclinical animal models, especially for the epileptic seizures of Dravet syndrome (a rare childhood syndrome characterized by severe encephalopathy and epilepsy) .
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【Collection】Super comprehensive cerebral artery blood supply distribution map
Time of Update: 2021-11-12
Midbrain blood supply areaMidbrain blood supply area midbrain blood supply area Five arteries supply the midbrain: the superior cerebellar artery (mainly the medial branch), the thalamic perforating artery, the posterior internal choroidal artery, the middle branch of the interpedal fossa from the posterior cerebral artery, and the anterior choroidal artery from the carotid system .
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EMA approves Ozawade to treat excessive daytime sleepiness (EDS)
Time of Update: 2021-11-12
Recently, the European Medicines Management Agency (EMA) has approved Bioprojet of Ozawade (pitolisant) for the treatment of obstructive sleep apnea (OSA) related to excessive daytime sleepiness (EDS) .
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Knowledge Collection!
Time of Update: 2021-11-12
Many kinds of brain development abnormalities can be manifested at the same time with enlarged lateral ventricles, including forebrain anemia, split brain malformation, anencephaly and giant gyrus .
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Neurology: What is the burden of different epilepsy patients?
Time of Update: 2021-11-12
In this study, researchers investigated the burden of chronic and acute diseases, injuries, and symptoms, and ethnic/ethnic differences in a large group of epilepsy patients receiving Medicaid .
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Movement Disorder: Glial cell imaging can identify Parkinson's and multiple system atrophy
Time of Update: 2021-11-12
In this way, Aurelija Jucaite and others of Karolinska University studied the diagnostic sensitivity and specificity of TSPO imaging between MSA and PD and MSA subtypes .
Glia Imaging Differentiates Multiple System Atrophy from Parkinson's Disease: A Positron Emission Tomography Study with 11C PBR28 and Machine Learning Analysis.
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Stroke: 10-year follow-up: What is the long-term significance of emergency secondary prevention after transient ischemic attack and minor stroke
Time of Update: 2021-11-12
Through the EXPRESS study, Ramon Luengo-Fernandez of Oxford University and others evaluated the short-term benefits of TIA/Mild Stroke Emergency Clinic in reducing the risk of recurrent stroke, reducing disability and hospital care costs over 10 years .
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Mov Disord: Genetic risk score helps stratify Parkinson's disease
Time of Update: 2021-11-12
The study proved the feasibility of the PD polygenic hazard approach, integrating genetic influences on disease risk and age of onset in a model .
This study proved the feasibility of the PD polygenic hazard method, integrating the genetic influence on disease risk and age of onset in a model .
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Stroke: Stroke patients, how do they recover after being discharged from the hospital?
Time of Update: 2021-11-12
manageThe significance of this study provides a set of key factors based on expert consensus that need to be considered when determining the location of care for stroke patients after discharge .
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Normal development of brain myelin sheath in children
Time of Update: 2021-11-12
At 4 months, slight hyperintensity on the T1 of the forelimb of the internal capsule, thickening of the myelin sheath in the central radial crown and semi-oval center, and myelination of the pressure part of the corpus callosum .
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Neurology: The relationship between the anatomical location of temporal lobe epilepsy surgery focus and the prognosis of postoperative epilepsy
Time of Update: 2021-11-12
Based on the evidence supporting the role of the medial temporal lobe cortex structure in TLE seizures , some researchers have recently hypothesized that the resection of the entorhinal and amygdala regions will be associated with further good postoperative results, and further hypothesized that the medial temporal bone structure and function are separated It is also independently related to better surgical results .
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Neurology: Bilateral structural network abnormalities in epilepsy with sulcus floor dysplasia
Time of Update: 2021-11-12
Recently, researchers have applied a technique called fixation-based analysis (FBA), which can identify specific white matter structures that exhibit clinically important structural connectivity reduction, thereby identifying the floor of the sulci The structure of white matter fiber tracts in patients with dysplasia (BOSD) is abnormal, and its relationship with seizure activity is discussed .
