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Excessive daytime sleepiness (EDS) is a condition that can cause people to feel very sleepy during the day
.
Patients may sleep longer at night, nap during the day, or fall asleep at unusual or inappropriate times
Usually, doctors can also prescribe neurostimulant drugs, such as modafinil (Provigil®) or methylphenidate (Ritalin®), to increase concentration and alertness
.
Patients should take the medicine as prescribed and consult a doctor or pharmacist before making any changes to the dosage or timing of the medicine
Recently, the European Medicines Management Agency (EMA) has approved Bioprojet of Ozawade (pitolisant) for the treatment of obstructive sleep apnea (OSA) related to excessive daytime sleepiness (EDS)
.
Ozawade was evaluated in two phase III clinical studies (HAROSA I and HAROSA II) for the treatment of EDS in patients with OSA
.
These two studies showed that the Epwoth Sleepiness Scale (ESS) score of patients treated with Ozawade had a "significant improvement", and no significant improvement was observed.
Two studies showed that the Epwoth Sleepiness Scale (ESS) score of patients treated with Ozawade had a “significant improvement”, and no significant improvement was observed.
Jean-Charles Schwartz, Scientific Director and Co-founder of Bioprojet, said: “Due to fatigue, excessive daytime sleepiness is the most frequently reported symptom of patients, which has a considerable impact on the quality of life and daily safety.
Ozawade provides an effective solution for all patients.
Regardless of whether they are receiving PPC treatment or are intolerant to this treatment"
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