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AJRCCM: What is pulmonary hypertension associated with neurofibromatosis type 1?
Time of Update: 2021-11-12
Respiratory complications, including pulmonary hypertension (PH), interstitial lung disease, airway plexiform neurofibroma, and intrathoracic meningocele, can develop gradually during a lifetime .
In all patients, we observed severe pulmonary vascular remodeling, characterized by thickening of the arterial and venous walls .
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Alz Res Therapy: Genetic risk score is closely related to phosphorylated tau protein in the blood
Time of Update: 2021-11-11
Data from the Alzheimer's Disease Neuroimaging Initiative (ADNI) was used to study the relationship between AD PRS (constructed based on the results of a recent genome-wide association study) and plasma p-tau181, using a linear regression model .
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JNER: Clinical validation of kinematic evaluation of upper limb movement after stroke using multi-joint arm exoskeleton
Time of Update: 2021-11-11
Five assessment tasks performed by subjects with exoskeletons A commercial (Armeo Spring, Hocoma, Volketswil, Switzerland) rehabilitation exoskeleton is used, with separate shoulder (arm rotation, arm elevation), elbow (FE) and wrist joints (FE, pronation/supination) The sensor provides gravity balance support for the paralyzed arm, and records kinematics and grip strength at the same time .
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Alz Res Therapy: a new type of cerebrospinal fluid protein that can effectively distinguish dementia from cognitive decline
Time of Update: 2021-11-11
Healthy control group, SCD, mild cognitive impairment (MCI), AD and non-AD dementia patients (cohort 2) .
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Lancet sub-Journal 500,000 people study: Vitamin D deficiency must be made up!
Time of Update: 2021-11-11
In summary, observational analysis shows that under the condition of low vitamin D concentration in the body , after vitamin D supplementation, the vitamin D concentration in the body is negatively correlated with the results of coronary heart disease, stroke and all-cause mortality .
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Alz Res Therapy: Simple cognitive scale test, or it may assist in screening Alzheimer's disease pathology screening
Time of Update: 2021-11-11
The important significance of this study lies in the discovery: BHA measures are significantly related to the in vivo imaging markers of Aβ and regional tau, which can be used to identify patients with suspected AD pathology in clinical practice .
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Clinical evaluation and treatment of ischemic penumbra of acute cerebral infarction, a list of the latest expert consensus recommendations
Time of Update: 2021-11-05
Under the leadership of the Neurologist Branch of the Chinese Medical Doctor Association, the cerebrovascular disease committee (scientific group) organized experts in related fields in China to write the following consensus after repeated discussions, for domestic counterparts to evaluate and treat acute cerebral infarction in clinical practice Refer to when the blood penumbra .
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With constant headaches, who is the real "culprit"?
Time of Update: 2021-11-05
The Journal of Neurology reported a case of a patient who had no previous history of headaches and presented to the doctor because of new-onset daily persistent headaches for 1 year .
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The patient was admitted to the hospital with a severe headache, and the doctor boldly used the questioned ancient therapy...
Time of Update: 2021-11-05
Zhang Xiang perfected the head MRI examination for the patient and found that it was a hemorrhagic infarction .
| Medical Micro Theory Chapter 11: When the diagnosis of the attending doctor and the head of the department is inconsistent.
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No side effects, the effect surpasses morphine!
Time of Update: 2021-11-05
The Swedish researcher found that a major breakthrough has been achieved through a new personalized electrode brain implant technology that can relieve severe pain without the common side effects usually associated with analgesics .
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This article explains the etiology of subarachnoid hemorrhage thoroughly!
Time of Update: 2021-11-05
Other causes include non-aneurysmal perimedullary hemorrhage, cerebral arteriovenous malformations (AVM), moyamoya disease (MMD), scleroderma Meningeal arteriovenous fistula (DAVF), vasculitis, intracranial venous system thrombosis, connective tissue diseases, intracranial tumors, hematological diseases, coagulopathy and complications of anticoagulation therapy, etc.
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JAMA Sub-Journal: Staying in space for a long time will cause brain damage
Time of Update: 2021-11-05
Recently, researchers from the University of Munich in Germany, the University of Gothenburg in Sweden and the Russian Academy of Sciences published a research paper titled: Changes in Blood Biomarkers of Brain Injury and Degeneration Following Long-Duration Spaceflight in the JAMA sub-Journal JAMA Neurology .
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Not paying attention to blood pressure control?
Time of Update: 2021-11-05
After adjusting for the influence of other factors, the researchers found that having high blood pressure is associated with an increased risk of dementia, especially in people aged 35-44 .
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Mol Psychiatry︱ Gao Tianming's research group reveals the different roles of astrocytes and neurons in synaptic plasticity and memory
Time of Update: 2021-11-05
Author ︱ Gao Tianming, edited by Liu Jihong ︱ Wang Sizhen Long-term potentiation (LTP) in the hippocampus is the most studied type of synaptic plasticity, and it is also considered to be a cellular mechanism of learning and memory [1] .
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Young man, be careful!
Time of Update: 2021-11-05
0000000000006947 The lead author of the report, Professor Nicolas Cherbuin of the Australian National University’s Centre for Aging, Health and Welfare, said that this study highlights young people in their 20s and 30s One issue that people need to pay special attention to is that the negative effects of elevated blood pressure take time to act on the brain .
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"Unequal pupils" for lightning protection in emergency consultations is a clinical necessity
Time of Update: 2021-11-05
3. Detection method: During the examination, the patient should relax and look at distant objects, avoid directly facing the light (may be caused by near pupil reflections to reduce pupils) .
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Does the brain also have fingerprints?
Time of Update: 2021-11-05
In a new study published in Science Advances, researchers found that it only takes 100 seconds to identify the unique fingerprint of the brain .
In the new study, the connection group data will change based on the activity being performed and which part of the brain is being used .
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"Chinese Multidisciplinary Diagnosis and Treatment Guidelines for Cerebral Hemorrhage Related to Blood Coagulation Dysfunction" is released!
Time of Update: 2021-11-05
01 Emergency treatment and evaluation of coagulation function (1) If the patient is found to be HDICH in the pre-hospital emergency, the specific name of the medication should be clarified, and the antiplatelet or anticoagulant drugs should be stopped immediately (level I recommendation, level C evidence) .
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Professor Zhen Zijun: Progress in maintenance treatment of high-risk neuroblastoma
Time of Update: 2021-11-05
During the conference, Yimaitong invited Professor Zhen Zijun from the Child Oncology Department of Sun Yat-sen University Cancer Center to share the progress of maintenance treatment for high-risk neuroblastoma .
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Nature cover is heavy!
Time of Update: 2021-11-05
Researchers such as Sjors HW Scheres and Michel Goedert of the University of Cambridge in the United Kingdom published articles on Nature, classifying "tau protein diseases" based on different protein folding structures, and they were featured on the cover of Nature .
