Young man, be careful!

Elevated blood pressure is a major health risk factor worldwide and the main cause of premature death
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Approximately 31% of adults worldwide suffer from hypertension, and another 25-50% are in prehypertension.
These people are at higher risk of stroke and cardiovascular disease
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As scientific research continues to advance, people have even found that rising blood pressure makes people "dumb" faster
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Recently, researchers from the Australian National University proposed that increased blood pressure is related to poorer brain health
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Compared with people with high blood pressure, the brains of those with ideal blood pressure levels will be more than 6 months younger in middle age
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Researchers suggest that the national health guidelines should be updated to remind people of the potential effects of elevated blood pressure and brain aging
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The related report was published online in the journal "Frontiers in Aging Neuroscience" with the title "Optimal Blood Pressure Keeps Our Brains Younger"
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https://doi.
org/10.
3389/fnagi.
2021.
694982 Hypertension has been proven to be a risk factor for dementia.
However, we do not know the time point and the extent of the impact of increased blood pressure on brain health
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At the same time, a large international study, PATH, found that the number of people over 30 with high blood pressure in the world has doubled
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DOI: 10.
1093/ije/dyr025 In order to further understand the impact of elevated blood pressure on brain health, the researchers screened some participants from PATH and constructed a fully validated brain age measurement method BrainAGE to conduct research
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During the trial, the researchers focused on the data of 335 middle-aged people aged 44-46 and 351 elderly people aged 60-64, and followed up these populations for up to 12 years, during which the participants accepted With up to four blood pressure assessments and two or more MRI brain scans, the researchers processed these data through the BrainAGE method to determine the brain age of the participants in the corresponding time period
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Judging from the characteristics of the participants’ population, the middle-aged group’s education level is higher than that of the elderly group, but the measured systolic and diastolic blood pressures are lower, and they are more likely to suffer from high blood pressure, take hypertensive drugs, or suffer from diabetes.
In addition, compared with female participants, male participants are more likely to develop high blood pressure
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During the demographic characteristics of the participants, the researchers used the omron sphygmomanometer to measure the sitting systolic and diastolic blood pressure (SBP/DBP) of the participant’s left upper arm, and passed 1/3(SBP) + 2/3(DBP) The formula of) calculates the participant’s mean arterial pressure (MAP)
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In general, SBP of 90-114 mmHg and DBP of 60-74 mmHg are the best blood pressure ranges.
At this time, MAP<90mmHg, and participants have the lowest risk of cardiovascular disease
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The statistical analysis of the participants’ blood pressure index and BrainAGE index shows that when the participant’s MAP exceeds 90 mmHg, every 1 mmHg increase in the value will increase the age of the participant’s brain by 5-7 days; at the optimal blood pressure level ( Participants with MBP <90, SBP <115, DBP <75) had a brain age that was more than 6 months younger than their peers; and this association was more significant among men than women
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Picture from: Anya Wotton/Australian National University.
It’s worth noting that the changes in blood pressure and brain age observed by researchers during the experiment did not differ significantly between the middle-aged group and the elderly group, indicating that elevated blood pressure has an effect on the brain Negative effects do not only appear in old age, but gradually appear throughout the life cycle of people
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As early as 2019, an article published by "Neurology" pointed out that in people aged 19-40, blood pressure ≥ 120/80 mm Hg is related to smaller brain gray matter volume, further highlighting the increase in blood pressure and brain health The relationship between
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https://doi.
org/10.
1212/WNL.
0000000000006947 The lead author of the report, Professor Nicolas Cherbuin of the Australian National University’s Centre for Aging, Health and Welfare, said that this study highlights young people in their 20s and 30s One issue that people need to pay special attention to is that the negative effects of elevated blood pressure take time to act on the brain
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"By detecting the impact of elevated blood pressure on the brain health of people in their 40s and older, we must assume that the effect of elevated blood pressure on the brain should gradually penetrate over the years, and perhaps this penetration has already occurred in people in their 20s.
At the beginning, this shows that young people’s brains are actually very fragile
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” Professor Cherbuin said
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In short, the latest research reminds us that the effect of elevated blood pressure on the brain is the result of long-term accumulation.
Even "young people" may be aggravating brain aging due to changes in blood pressure
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Regardless of the age group, blood pressure should be checked regularly to deal with the aging of the brain in advance
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End Reference: [1]https://medicalxpress.
com/news/2021-10-optimal-blood-pressure-brains-age.
html[2]https:// .
2021.
694982/full#B17[3]https://n.
neurology.
org/content/92/8/e758