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Alz Res Therapy: a new type of cerebrospinal fluid protein that can effectively distinguish dementia from cognitive decline

 Last Update: 2021-11-11
 Source: Internet
 Author: User

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tyrosine amino acid

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Tau pathology, in the form of neurofibrillary tangles (NFT) of hyperphosphorylated tau, together with amyloid beta (Aβ) plaques, is one of the hallmarks of Alzheimer's disease (AD)

On the other hand, Aβ42 showed a decrease in CSF level

immunity

However, some studies have shown that tau in CSF is very heterogeneous.

In a recent study, Kaj et al.

diagnosis

In the non-AD group, N-224 was found in Parkinson’s disease (PD, p <0.

The important significance of this study lies in the discovery: N-224 tau can distinguish AD subjects from SCD, and can distinguish between subgroups of non-AD dementia and AD

N-224 tau can distinguish AD subjects from SCD, and can distinguish subgroups of non-AD dementia and AD

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