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Science Sub-Journal: Aspirin relieves symptoms of neuropsychiatric diseases caused by high-sugar diet
Time of Update: 2021-12-08
Researchers found that low-dose aspirin can completely alleviate hyperactivity, repetitive stereotyped behaviors, cognitive learning disabilities in GLO1 knockout mice on a sucrose diet, and reduce fibrin deposition, partially alleviating glucose uptake .
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Nat. Commun Li Haohong/Shen Wei discovered the essential coding law of instinctive behavior
Time of Update: 2021-12-08
Multi-channel recording experiments show that the six neuron clusters in LPAG respectively encode the search, tracking and attack phases of predation in a strict time sequence .
All in all, the study reveals the mechanism by which LPAG neuron clusters encode predation sequences, providing an example of decoding complex instinctive behaviors .
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JEM Yan Min/Tao Yuanxiang team collaborates to reveal the three-dimensional regulatory molecular mechanism of neuropathic pain
Time of Update: 2021-12-08
This article explains the role and mechanism of the zinc finger protein transcription factor ZNF382 in the pathogenesis of neuropathic pain caused by nerve injury from the perspectives of genomic functional elements, chromatin spatial conformation and epigenetic regulation.
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"Nature": Two hours of cognitive training can make the brain more focused and smarter?
Time of Update: 2021-12-08
Through experiments on mice, researchers have shown that cognitive training with the design goal of "focusing on the focus and reducing distractions" can help the brain enhance its information processing capabilities and promote the ability to learn new tasks in a new environment .
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Li Haohong of Zhejiang University/Shen Wei of ShanghaiTech University jointly decrypts the neural mechanism of predation programming
Time of Update: 2021-12-08
In summary, this article reveals that excitatory neurons and inhibitory neurons in the LPAG brain region regulate different stages of predation behavior.
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Adv Sci from the research group of Professor Qin Ling, The Chinese University of Hong Kong
Time of Update: 2021-12-08
Abstract: The team of Professor Qin Ling from the Chinese University of Hong Kong, together with Professor Jufang He from City University of Hong Kong and Professor Jie Zhao from Shanghai Jiaotong Un
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Science Neurobiology Award: Hunger, Central Nervous System Immunity, and "Seeing"
Time of Update: 2021-12-08
Original link: https:// Intestinal-brain signals and food intake hunger circuits can have a profound effect on the body's sensory response, but how does sensory stimulation affect the neural activity of the hunger circuit?
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Experts comment on Nat Biotechnol's Li Yulong laboratory to develop a new fluorescent probe for detecting the spatiotemporal dynamics of endocannabinoids
Time of Update: 2021-12-08
On November 11, 2021, Peking University's Li Yulong Laboratory published a research paper entitled A fluorescent sensor for spatiotemporally resolved imaging of endocannabinoid dynamics in vivo in Nature Biotechnology, reporting a new gene-encoded endocannabinoid probe GRABeCB2 .
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Nature Sub-Journal: Combining artificial intelligence and brain electrical stimulation to improve human brain function
Time of Update: 2021-12-07
In this study, the research team combined artificial intelligence with targeted brain electrical stimulation, showing that precisely directed electrical stimulation can reliably enhance specific human mental functions related to mental illness, and that there are specific sub-capsules in the brain capsule structure.
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Nature Sub-Journal: Professor Yin Dongmin from East China Normal University reveals that dopamine receptors regulate synaptic pruning
Time of Update: 2021-12-07
After continuous injection of Drd2 antagonist into the ACC brain area of 3-week-old rats (before the disappearance of the synapses), the dendritic spine density of neurons increased at the 5th week, excitatory postsynaptic currents increased, and inhibitory synapses There is no change in current, and glutamatergic transmission is enhanced, which is consistent with the result caused by gene knockdown of Drd2 .
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Nat Neurosci Army Medical University Chen Xiaowei and other teams discovered new targets that affect memory maintenance
Time of Update: 2021-12-07
On November 15, 2021, Chen Xiaowei, Army Medical University and Arthur Konnerth of Technical University of Munich, Germany, jointly published an online report entitled "Fear learning induces α7-nicotinic acetylcholine receptor-mediated astrocytic responsiveness that is required for memory persistence" in Nature Neuroscience.
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[PNAS] Explore brain "events"-do you know what happens in the brain?
Time of Update: 2021-12-07
Computational neuroscientists Maria Pope, Richard Betzel, and Olaf Sporns of Indiana University are using a new model of brain activity to explore an astonishing burst of activity in the human brain that has never been examined .
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New Discovery in Neuron︱Nobel Prize Lab!
Time of Update: 2021-12-07
They used the Inscopix free activity calcium imaging microscope to record the neural activity of the hippocampus CA1 and found that path integration imposes spatial meaning on odor cues, thereby creating new location markers, greatly improving navigation capabilities, and the same odor appears in different locations It also produced the characterization of different Place Cells .
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Electroacupuncture therapy suppresses inflammation by activating neurons
Time of Update: 2021-12-07
It was previously discovered that the vagus nerve-adrenal network activated by low-intensity electric acupuncture stimulation on Zusanli produced anti-inflammatory effects by inducing the adrenal glands to secrete catecholamine molecules [7] .
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Professor Yu Yinghua/Zheng Kuiyang from Xuzhou Medical University reveals that the lack of dietary fiber causes cognitive dysfunction
Time of Update: 2021-12-07
In summary, this article reveals the mechanism by which long-term dietary fiber-deficient diets cause cognitive dysfunction in mice: the loss of synapses mediated by microglia in the hippocampus .
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For stroke prevention in the elderly, these 7 questions must be mastered!
Time of Update: 2021-12-06
A meta-analysis showed that for all patients with asymptomatic carotid stenosis, CAS (≈4%) has a higher 10-year risk of stroke or death than CEA (≈2.
Another 2016 meta-analysis found that among patients over 75 years of age, the risk of stroke from CAS is much higher than that of CEA .
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Two "Nature" on the same day!
Time of Update: 2021-12-06
▲Under cryo-electron microscopy, the structure formed by the combination of MRGPRX2 and ligand (picture source: Reference [1]) Scientists have noticed clinically that certain drugs will also activate the MRGPRX2 receptor, triggering the release of histamine, which induces itching Side effects .
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PLOS Medicine: Coffee, tea, coffee + tea can all reduce the risk of stroke and dementia!
Time of Update: 2021-12-06
In addition, the combination of coffee and tea intake is associated with a lower risk of vascular dementia, but not with Alzheimer's disease .
After multivariate adjustment, participants who drank 2 to 3 cups of coffee a day were associated with a lower risk of dementia compared with non-coffee drinkers (HR, 0.
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Mechanism of obesity caused by insufficient dose of Sci Adv SIM1 haploid
Time of Update: 2021-12-06
Recently, the Chi-Chung Hui research group from the University of Toronto and the Toronto Sick Children’s Hospital published an article titled Ectopic expression of Irx3 and Irx5 in the paraventricular nucleus of the hypothalamus contributes to defects in Sim1 haploinsufficiency on Science Advances.
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The latest research shows that drinking coffee and tea can effectively reduce the risk of stroke and dementia!
Time of Update: 2021-12-06
Research has shown that drinking coffee and tea can reduce the risk of stroke and dementia .
In summary, studies have shown that drinking coffee and tea alone or in combination can effectively reduce the risk of stroke and dementia .
