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ARD: Low rates of somatic NLRC4 mutations cause late-onset autoinflammatory disease
Time of Update: 2022-08-19
Conclusions: This study reports a case of late-onset autoinflammatory disease caused by somatic NLRC4 mutations in a small subset of leukocytes .
Conclusions: This study reports a case of late-onset autoinflammatory disease caused by somatic NLRC4 mutations in a small subset of leukocytes .
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ARD: Deletion of Mesenchymal Activin A Ameliorates Disease Severity in Experimental Arthritis
Time of Update: 2022-08-19
d/d ColVI-Cre) but not in myeloid cells (ActβA d/dd/dConclusions: The results highly suggest that FLS-produced activin A plays a crucial paracrine role in inflammatory joint destruction and may be useful in the treatment of inflammatory diseases (such as rheumatoid arthritis) associated with OC formation and bone destruction.
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Rheumatology: application experience of mycophenolate mofetil in adolescent idiopathic inflammatory myopathy
Time of Update: 2022-08-19
1093/rheumatology /keac404 Objective: To evaluate the efficacy and safety of mycophenolate mofetil (MMF) in the treatment of juvenile idiopathic inflammatory myopathy (JIIM) .
1093/rheumatology /keac404 Objective: To evaluate the efficacy and safety of mycophenolate mofetil (MMF) in the treatment of juvenile idiopathic inflammatory myopathy (JIIM) .
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Are vitamins the "Wolf Warrior" medicine?
Time of Update: 2022-08-19
Video applet like, double-tap to cancel the like and watch, double-tap to cancel the view In the growth and development of the human body, vitamins are an indispensable substance to maintain human life activities and enhance disease resistance.
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Rheumatology: Autologous stem cell transplantation mobilized with low-dose cyclophosphamide is feasible in patients with systemic sclerosis
Time of Update: 2022-08-19
Objective: To evaluate the feasibility of reducing the dose of cyclophosphamide in patients with systemic sclerosis during high-dose chemotherapy and autologous stem cell transplantation before mobilizing chemotherapy .
Lower body weight and body mass index (p2 consecutive days) was analyzed for the occurrence of ; compared the mobilization effect of low-dose (2*1-1.
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Rheumatology: Low-dose rituximab is effective in refractory idiopathic inflammatory myopathy
Time of Update: 2022-08-19
1093/rheumatology/keac438 OBJECTIVE: The early use of rituximab (RTX) in refractory idiopathic inflammatory myopathy (IIM) has not been well studied .
1093/rheumatology/keac438 OBJECTIVE: The early use of rituximab (RTX) in refractory idiopathic inflammatory myopathy (IIM) has not been well studied .
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Osteoarthritis (OA)
Time of Update: 2022-08-19
1. Definition of Osteoarthritis:Osteoarthritis diagnosis and treatment guidelines (2007 edition) definition: OA refers to joint diseases caused by articular cartilage fibrosis, chapped, ulcers, and loss caused by various factors .
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A&R: The role of genetics in the development of clinically suspected arthralgia and rheumatoid arthritis, a large cross-sectional study
Time of Update: 2022-08-19
Patients with CSA were assessed for inflammatory arthritis transformation over a 2-year period, and after 2 years they were classified as either convertor (CSAc, N=84) or non-transformer (CSAnc, N=395) .
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Nature: Li Jin's team reveals RNA editing is the basis of genetic risk for common inflammatory diseases
Time of Update: 2022-08-19
This study demonstrates that adenosine-inosine (A→I) RNA editing mediated by the RNA editing protein ADAR is an important post-transcriptional event that prevents the cell's own double-stranded RNA (dsRNA) from triggering an innate immune interferon response, caused by genetic factors Decreased levels of double-stranded RNA editing are an important factor in increasing the genetic risk of inflammatory diseases .
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These 6 ways to prevent kidney failure in lupus patients, the sooner you look at it, the more useful it is!
Time of Update: 2022-08-19
To control salt intake, daily can [2]: 02Reduce urinary proteinUrinary protein is a marker of kidney damage and an independent risk factor for the progression of chronic renal failure .
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J Autoimmunity: Modulation of T cell activation with antisense oligonucleotides targeting lymphocyte cytoplasmic protein 2
Time of Update: 2022-08-19
In this study, a research team from Sweden and Singapore explored an alternative drug model, developed an antisense oligonucleotide (ASO) targeting LCP2 mRNA, and assessed its activity in regulating T cell activation .
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J Autoimmunity: Nuclear translocation of RIG-I promotes apoptosis
Time of Update: 2022-08-19
In this study, Cao Xuetao's team reported that RIG-I induced nuclear translocation in the late stage of viral infection .
In this study, Cao Xuetao's team reported that RIG-I induced nuclear translocation in the late stage of viral infection .
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J Autoimmunity: A panel of type II interferon-regulated genes is associated with disease activity in patients with systemic lupus erythematosus
Time of Update: 2022-08-19
Objective: Upregulation of interferon-regulated genes (IRGs) in peripheral blood, expressed as an interferon (IFN) signature, has been used as an indirect measure of IFN pathway activation in patients with systemic lupus erythematosus (SLE) .
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Front Cell Infect Microbiol: Porphyromonas gingivalis infection increases risk of rheumatoid arthritis
Time of Update: 2022-08-19
A meta-analysis published in Front Cell Infect Microbiol systematically analyzed the association between Porphyromonas gingivalis exposure and the prevalence of rheumatoid arthritis .
A meta-analysis published in Front Cell Infect Microbiol systematically analyzed the association between Porphyromonas gingivalis exposure and the prevalence of rheumatoid arthritis .
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Exercise program for patients with rheumatoid arthritis
Time of Update: 2022-08-19
◎ Exercise intensity and time◎ Remember when exercising: Exercise, like diet, has always been a topic of concern for rheumatoid arthritis patients .
◎ Exercise intensity and time◎ Remember when exercising: Exercise, like diet, has always been a topic of concern for rheumatoid arthritis patients .
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Summer precautions for patients with ankylosing spondylitis and rheumatoid arthritis
Time of Update: 2022-08-19
Do not expose joints in the air-conditioned room, wear long clothes and trousers or prepare a thin blanket, joint care and coolness are both good, but don't stay in the air-conditioned room for too long~02Wash your feet and soak your ankles in warm waterIn summer, most of the climate is humid, and it is best to use warm water bubbles after going out and returning home .
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Shanghai Materia Medica: Anti-inflammatory and Pain Relief See Turmeric
Time of Update: 2022-08-19
Video applet like, double-tap to cancel the like and watch, double-tap to cancel the view Curcumin, as a natural compound, is slowly entering the public's field of vision.
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Lupus diet these 4 kinds of hair products you banned right?
Time of Update: 2022-08-19
Dr. Huang Runyue told everyone that you should pay attention to the following 4 points:01 Avoid eating hairy foods In a 2015 study on the pathogenesis of systemic lupus erythematosus, it was found that a questionnaire survey was conducted on 30 patients with systemic lupus erythematosus and 30 normal people, and the results showed that diet is an important risk factor .
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Why does rheumatoid arthritis have the phenomenon of "different drugs for the same disease"?
Time of Update: 2022-08-19
Video applet like, double-tap to cancel the like and watch, double-tap to cancel the view Feedback: When chatting with patients, you will find that everyone has the same disease - rheumatoid arthritis, and may see the same rheumatologist, but sometimes the medication is different .
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Prairie Medical Talk: How to safely get pregnant in patients with systemic lupus erythematosus?
Time of Update: 2022-08-19
Video applet like, double-tap to cancel the like and watch, double-tap to cancel the view Systemic lupus erythematosus occurs in women of childbearing age and can cause multiple organ and organ involvement .
