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Science sub-issue cover: Ebola virus can hide in the brain and even persist for years after treatment
Time of Update: 2022-03-08
Over the past few years, Qinghong Zeng's team at the American Academy of Medicine has used nonhuman primate survivors as models to systematically study the persistence of the Ebola virus .
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Rapeseed team makes progress in functional study of phospholipase and its hydrolyzate
Time of Update: 2022-03-08
Figure 1 Types of plant phospholipases and their catalytic sitesThis review provides a comprehensive introduction to the research progress of the plant phospholipase family, which is divided into different subgroups according to PLA, PLC and PLD protein sequences, conserved domains, mechanisms of action, substrate specificity and enzymatic reaction requirements and their physiological functions family .
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Science Shanghai Institute of Materia Medica jointly tackled the new coronavirus Omicron variant spike protein and its complex structure with receptors and antiviral antibodies, and revealed the mechanism of action
Time of Update: 2022-03-08
Facing the severe situation of epidemic prevention and control, the team of Xu Huaqiang and Yin Wanchao from Shanghai Institute of Materia Medica, Chinese Academy of Sciences urgently tackled key problems and quickly analyzed the high-resolution cryo-EM structure of the spike protein of the Omicron variant and the human receptor ACE2 (Figure 1A and 1B) .
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The team of Gao Xin from Suzhou Institute of Medical Technology proposes a new method for intelligent pathological diagnosis of melanocytic lesions
Time of Update: 2022-03-08
In response to the above problems, the Suzhou Institute of Medicine and Engineering of the Chinese Academy of Sciences and the Department of Pathology of the Ninth People's Hospital Affiliated to Shanghai Jiaotong University School of Medicine proposed a new fully automatic and intelligent pathological diagnosis method for melanocytic lesions (as shown in Figure 2 ) .
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The team of Chen Shuqing/Pan Liqiang from Zhejiang University School of Pharmacy received "Signal Transduction and Targeted...
Time of Update: 2022-03-08
On February 7 , 2022 , at the invitation of the editor-in-chief Academician Wei Yuquan, Professor Shuqing Chen and researcher Pan Liqiang from the School of Pharmacy, Zhejiang University published an online publication entitled " Emerging new therapeutic antibody " in the journal " Signal Transduction and Targeted Therapy " under the Nature Publishing Group.
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Seeing the 'starry sky' in the brain: Astrocytes show unique activity patterns
Time of Update: 2022-03-08
Image: Astrocytes (meaning "star cells") have a unique morphology . Although the inner structure is star-shaped, the cells' tiny protrusions form cloud-like regions that enclose all nearby synapse
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"CellRepo" global knowledge base for cell engineering
Time of Update: 2022-03-08
The database tracks and organizes digital data generated during cell engineering, reports a new study published in the journal Nature Communications .
Scientists believe that version control for cell engineering will make engineering biology more open, reproducible, easier to track and share, and more trustworthy .
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Yin Yuxin's team discovered a new anti-cancer mechanism of PTEN gene: inhibiting tumor invasion and metastasis by encoding circular RNA circPTEN1
Time of Update: 2022-03-08
On February 8, 2022, Professor Yin Yuxin's team from Peking University School of Basic Medicine published a paper entitled " circPTEN1 , a circular RNA generated from PTEN, suppresses cancer progression through inhibition of TGF-β/Smad signaling" in Molecular Cancer .
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Gene-edited wheat fights dreaded fungus without pesticides
Time of Update: 2022-03-08
A few years ago, Caixia Gao, a plant scientist at the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences, and her colleagues set out to study the genes involved in wheat yield and disease resistance .
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A novel anticancer mechanism of PTEN gene: inhibition of tumor invasion and metastasis by encoding circular RNA circPTEN1
Time of Update: 2022-03-08
On February 8, 2022, Professor Yin Yuxin's team from Peking University School of Basic Medicine published a research paper titled "circPTEN1, a circular RNA generated from PTEN, suppresses cancer progression through inhibition of TGF-β/Smad signaling" in Molecular Cancer .
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Nature Communications ｜Light regulates parathyroid hormone secretion to interfere with bone loss
Time of Update: 2022-03-08
On February 9, 2022, Beijing time, Yang Fan's research group from the Institute of Brain Cognition and Brain Diseases, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, and Shenzhen-Hong Kong Brain Science Innovation Research Institute published an article entitled "An optogenetic approach for regulating human parathyroid" in Nature Communications The latest research results of hormone secretion" .
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Multi-year rainfall reduction treatments lead to carbon dynamics in Xishuangbanna tropical rainforest...
Time of Update: 2022-03-08
On the other hand, since the negative impact of simulated drought on plant carbon sinks did not gradually show until the eighth year of water control, it can be considered that the Xishuangbanna tropical rain forest has a certain resistance to drought .
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Cell Inspired by renowned cancer scientists: Immune cells leave traces on tumors that have metastasized to the brain
Time of Update: 2022-03-08
"Inspiration from renowned cancer researchers"Zena Werb was the first to see the potential and feasibility of collecting human metastases and combining it with cutting-edge technologies such as single-cell transcriptomics and cytology," Gonzalez said.
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Lin Hongxuan's research group reveals a new mechanism by which G protein regulates wax synthesis through calcium signaling and thus regulates heat tolerance in rice
Time of Update: 2022-03-08
When the function of TT2 is lost, the heat-induced calcium signal is weakened, which in turn weakens the interaction between SCT1 and CaM, reduces the inhibition of SCT1 transcriptional activity by CaM, and finally maintains the normal expression and stable wax content of OsWR2 under high temperature stress.
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Zhou Bin's group collaborated to reveal a new mechanism of coronary angiogenesis in mammalian neonatal hearts
Time of Update: 2022-03-08
TRS_Editor A{font-family:;font-size:12pt;}</> On February 4th, the international academic journal Circulation Research published the latest research titled "Extension of Endocardium-derived Vessels Generate Coronary Arteries in Neonates" by Zhou Bin's research group of the Center for Excellence in Molecular and Cell Science, Chinese Academy of Sciences and Luo Qingming's research group of Hainan University as a cover article.
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No obvious phylogenetic pattern of Ficus alpine trees in the India-Myanmar region
Time of Update: 2022-03-08
Assistant researcher Huang Jianfeng from the Co-evolutionary Research Group of the Banna Botanical Garden analyzed the genetic diversity distribution pattern and phylogenetic structure of Ficus alpine in the India-Myanmar region through extensive and representative population sampling .
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Associate Professor Zhang Xin's research group published an article in Computers in Human Behavior, proposing new strategies to reduce the elderly's fear of technology
Time of Update: 2022-03-08
Recently, Computers in Human Behavior published an article by Associate Professor Zhang Xin's research group When less intergenerational closeness helps: The influence of intergenerational physical proximity and technology attributes on technophobia among older adults .
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USTC has made important progress in tumor tissue microscopic magnetic imaging technology
Time of Update: 2022-03-08
, in cooperation with Professor Wei Haiming from the Department of Life Science and Medicine, have made important progress in the biomedical application of diamond nitrogen-vacancy color center quantum precision measurement technology, and established the first tumor Tissue immunomagnetic microscopy imaging technology realizes magnetic imaging with micron resolution at the tissue level, which has the advantages of high stability, low background and absolute quantification of tumor markers, and simultaneously realizes multimodal imaging of magnetic and optical .
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Wu Hong's group and collaborators from the School of Life Sciences reveal high-risk gene mutations in T-cell acute lymphoblastic leukemia in Chinese populations
Time of Update: 2022-03-08
Combined with clinical data, the researchers further found that RAS pathway mutations were associated with poor prognosis in non-TAL subtypes through survival analysis, and PTEN mutations were associated with poor prognosis in patients with TAL subtypes .
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CD97 promotes splenic dendritic cell homeostasis through mechanosensing of erythrocytes
Time of Update: 2022-03-08
CD97 signaling enables cDC2s to localize at the tissue-blood interface, a location that optimizes antigen capture and mounts a rapid immune response to systemic pathogens .
We found that type 2 conventional DCs (cDC2s) of the spleen are Gα-dependent13and adhesion G protein-coupled receptor family member-E5 (Adgre5, or CD97) localizes to blood-exposed sites .
