-
Cell Inspired by renowned cancer scientists: Immune cells leave traces on tumors that have metastasized to the brain
Time of Update: 2022-03-08
"Inspiration from renowned cancer researchers"Zena Werb was the first to see the potential and feasibility of collecting human metastases and combining it with cutting-edge technologies such as single-cell transcriptomics and cytology," Gonzalez said.
-
The team of Gao Xin from Suzhou Institute of Medical Technology proposes a new method for intelligent pathological diagnosis of melanocytic lesions
Time of Update: 2022-03-08
In response to the above problems, the Suzhou Institute of Medicine and Engineering of the Chinese Academy of Sciences and the Department of Pathology of the Ninth People's Hospital Affiliated to Shanghai Jiaotong University School of Medicine proposed a new fully automatic and intelligent pathological diagnosis method for melanocytic lesions (as shown in Figure 2 ) .
-
Clearing senescent stem cells from the brain enhances neurogenesis and cognitive function
Time of Update: 2022-03-08
In this study, the team tested the negative effects of aging in the neural stem cell niche on normal stem cell function and adult neurogenesis in the brains of middle-aged mice .
-
The research team of Professor Song Huaidong of the Ninth Affiliated Hospital found a new pathogenic mechanism and potential therapeutic target of "Hashimoto's thyroiditis"
Time of Update: 2022-03-08
At 5:00 EST on February 9, 2022, "Nature Communications", a sub-journal of "Nature", published the research paper "Lymphocyte Infiltration and Thyrocyte Destruction is Driven by Stromal" by Professor Song Huaidong's research team from the Ninth People's Hospital affiliated to Shanghai Jiaotong University School of Medicine and Immune Cell Components in Hashimoto's Thyroiditis" .
-
Gene-edited wheat fights dreaded fungus without pesticides
Time of Update: 2022-03-08
A few years ago, Caixia Gao, a plant scientist at the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences, and her colleagues set out to study the genes involved in wheat yield and disease resistance .
-
Multi-year rainfall reduction treatments lead to carbon dynamics in Xishuangbanna tropical rainforest...
Time of Update: 2022-03-08
On the other hand, since the negative impact of simulated drought on plant carbon sinks did not gradually show until the eighth year of water control, it can be considered that the Xishuangbanna tropical rain forest has a certain resistance to drought .
-
The team of Chen Shuqing/Pan Liqiang from Zhejiang University School of Pharmacy received "Signal Transduction and Targeted...
Time of Update: 2022-03-08
On February 7 , 2022 , at the invitation of the editor-in-chief Academician Wei Yuquan, Professor Shuqing Chen and researcher Pan Liqiang from the School of Pharmacy, Zhejiang University published an online publication entitled " Emerging new therapeutic antibody " in the journal " Signal Transduction and Targeted Therapy " under the Nature Publishing Group.
-
Nature Communications ｜Light regulates parathyroid hormone secretion to interfere with bone loss
Time of Update: 2022-03-08
On February 9, 2022, Beijing time, Yang Fan's research group from the Institute of Brain Cognition and Brain Diseases, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, and Shenzhen-Hong Kong Brain Science Innovation Research Institute published an article entitled "An optogenetic approach for regulating human parathyroid" in Nature Communications The latest research results of hormone secretion" .
-
"CellRepo" global knowledge base for cell engineering
Time of Update: 2022-03-08
The database tracks and organizes digital data generated during cell engineering, reports a new study published in the journal Nature Communications .
Scientists believe that version control for cell engineering will make engineering biology more open, reproducible, easier to track and share, and more trustworthy .
-
Pure hair!
Time of Update: 2022-03-08
Researchers at the company have transplanted hair stem cells into mice, allowing hairless mice to grow human hair .
When Professor Kohler initially worked on treating deafness, he wanted to grow hair-like cells inside the ear, but the organoids he grew ended up being skin with hair follicles .
-
Yin Yuxin's team discovered a new anti-cancer mechanism of PTEN gene: inhibiting tumor invasion and metastasis by encoding circular RNA circPTEN1
Time of Update: 2022-03-08
On February 8, 2022, Professor Yin Yuxin's team from Peking University School of Basic Medicine published a paper entitled " circPTEN1 , a circular RNA generated from PTEN, suppresses cancer progression through inhibition of TGF-β/Smad signaling" in Molecular Cancer .
-
Mechanisms of spindle pole organization and instability in human oocytes
Time of Update: 2022-03-08
Our data also elucidate one cause of spindle instability in human oocytes: Human oocytes lack KIFC1, a key spindle-stabilizing protein in other mammalian oocytes and cancer cells .
-
Seeing the 'starry sky' in the brain: Astrocytes show unique activity patterns
Time of Update: 2022-03-08
Image: Astrocytes (meaning "star cells") have a unique morphology . Although the inner structure is star-shaped, the cells' tiny protrusions form cloud-like regions that enclose all nearby synapse
-
PNAS: Chinese Academy of Sciences scholars reveal the regulatory mechanism of breast cancer-related macrophages
Time of Update: 2022-03-08
On January 31, 2022, the international academic journal PNAS published online the latest research results of Hu Guohong's research group from Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, entitled "miR-182 targeting reprograms tumor-associated macrophages and limits breast cancer progression", which clarified Novel regulatory mechanism and targeted therapy strategy of tumor-associated macrophages in breast cancer .
-
Lin Hongxuan's research group reveals a new mechanism by which G protein regulates wax synthesis through calcium signaling and thus regulates heat tolerance in rice
Time of Update: 2022-03-08
When the function of TT2 is lost, the heat-induced calcium signal is weakened, which in turn weakens the interaction between SCT1 and CaM, reduces the inhibition of SCT1 transcriptional activity by CaM, and finally maintains the normal expression and stable wax content of OsWR2 under high temperature stress.
-
Remove the "sugar-coated" CAR-T from tumor cells and become a "cannonball"!
Time of Update: 2022-03-08
Gene variants associated with N-glycan synthesis and prognosis in patients with pancreatic cancer (Source: STM)After knocking out MGAT5, it was found that the anti-tumor effect of CAR-T cells 44v6.
-
The research group of Ryuichi Shinto, a tenured associate professor at the Center for Quantum Materials Science, School of Physics, proposes that the emerging superfluidity in two-dimensional materials can realize the dissipation-free conversion of magnetic spin and charge
Time of Update: 2022-03-08
Ryuichi Shindou, a tenured associate professor at the Center for Quantum Materials Science, School of Physics, Peking University, and Zhang Yeyang, a 2020 doctoral student, proposed that exciton condensates in two-dimensional electron-hole bilayer (EHDL) systems are the key to realizing spin The ideal platform for dissipationless conversion of voltage and current .
-
Science Shanghai Institute of Materia Medica jointly tackled the new coronavirus Omicron variant spike protein and its complex structure with receptors and antiviral antibodies, and revealed the mechanism of action
Time of Update: 2022-03-08
Facing the severe situation of epidemic prevention and control, the team of Xu Huaqiang and Yin Wanchao from Shanghai Institute of Materia Medica, Chinese Academy of Sciences urgently tackled key problems and quickly analyzed the high-resolution cryo-EM structure of the spike protein of the Omicron variant and the human receptor ACE2 (Figure 1A and 1B) .
-
Fang Jingyun and collaborators from the School of Urban and Environmental Sciences systematically sort out the research on carbon sinks in terrestrial ecosystems to help achieve the goal of "carbon neutrality"
Time of Update: 2022-03-08
"Terrestrial carbon sinks in China and around the world and their contribution to carbon neutrality", a review of terrestrial ecosystem carbon sinks co-authored by 28 researchers including Yang Yuanhe, Shi Yue, Sun Wenjuan and Chang Jinfeng from Zhejiang University [ Yang, Y.
-
A novel anticancer mechanism of PTEN gene: inhibition of tumor invasion and metastasis by encoding circular RNA circPTEN1
Time of Update: 2022-03-08
On February 8, 2022, Professor Yin Yuxin's team from Peking University School of Basic Medicine published a research paper titled "circPTEN1, a circular RNA generated from PTEN, suppresses cancer progression through inhibition of TGF-β/Smad signaling" in Molecular Cancer .
