-
Nautre: The deeper cause of avoidance of social interaction, social stress impairs social reward and then triggers social avoidance
Time of Update: 2023-02-03
Click on the blue word to follow usSocial avoidance is a common phenomenon in many mental disorders, which is manifested as a lack of interest in social activities, and even the appearance of social a
-
Hailiang Zhu / Zhongchang Wang AS, Nanjing University: Application of protein nanomaterials in the treatment of brain glioma
Time of Update: 2023-02-03
Innovation: Hailiang Zhu, Zhongchang Wang and their collaborators of Nanjing University constructed an endogenous stimulus-responsive multifunctional nanodrug-loading platform for transferrin-mediated in situ glioma, which solved the problems of drug crossing the blood-brain barrier, targeted sustained and controlled-release drugs, image tracing and tumor hypoxia, and realized the synergistic enhancement of the effect of photodynamic therapy combined with chemotherapy.
-
First, clarify thrombolytic and anticoagulant therapy for stroke caused by atrial fibrillation
Time of Update: 2023-02-03
*For medical professionals onlyThrombolytic and anticoagulant therapy for stroke caused by atrial fibrillationWritten by | Bi GuangyiCardioembolic stroke (CES), abbreviated as cardiogenic stroke, refe
-
Today, Science discovers a new brain structure! Rediscover the protective barrier of the brain
Time of Update: 2023-02-03
On the other hand,SLYM contains a large number of central nervous system immune cells, which are monitored on the surface of the large brain by SLYMto scan the cerebrospinal fluid flowing through it for signs of infection.
-
STTT Academician Bian Xiuwu and other teams have revealed the underlying mechanism of neurological symptoms caused by the new coronavirus
Time of Update: 2023-02-03
Neuronal and myelin damage associated with abnormal protein expression in the COVID-19 brain (Image from Signal Transduction and Targeted Therapy)In summary, this study defines the neuropathological nature of the brain as COVID-19-associated monocytic encephalitis, which may be caused by aseptic perivascular and parenchymal inflammation, Endothelial cell infection with SARS-CoV-2, hypoxic-ischemic encephalopathy, and secondary infection with lung microorganisms.
-
AD: VD levels in the brain are very important! The first quantitative study found that a doubling of vitamin D levels in the brain was associated with a 33% lower risk of dementia or mild cognitive impairment
Time of Update: 2023-02-03
After comparing the results of the subjects' last cognitive test before death, the researchers found that a 1-fold increase in brain 25(OH)D3 levels in four brain regions was associated with a 25 to 33 percent reduction in the incidence of dementia or mild cognitive impairment (OR, 0.
-
Shi Yigong's team discovered the APOE4 receptor, revealing the cause of the strongest risk factor for Alzheimer's disease
Time of Update: 2023-02-03
Link to the paper: style="letter-spacing: normal;color: rgb(136, 136, 136);font-size: 12px;" _mstmutation="1" _istranslated="1"> Open reprint, welcome to forward to Moments and WeChat groups The study demonstrated that APOE4 specifically interacts with LilrB3(leukocyte immunoglobulin-like receptor B3).
-
"Yangkang" Those rare headaches you should know
Time of Update: 2023-02-03
Fig. 6 Compound analgesic overuse headachebrief summaryThe above types of headaches are not necessarily related to "yang", but it can be found from the clinical practice that many patients will stack their own ingredients and drugs with similar effects after taking a fever-reducing drug/painkiller with poor effect, or take it at the same time as Chinese proprietary medicine, and some proprietary Chinese medicines are compound preparations, which contain Western medicine ingredients and are prone to drug overdose.
-
Neuron Tang Yamei's team discovered a new mechanism by which microglia infiltrate the brain parenchyma through chemotaxis peripheral CD8+ T cells
Time of Update: 2023-02-03
Radiation-induced brain injury (RIBI) is a serious complication of radiotherapy for head and neck tumors, mostly 3-5 years after the end of radiotherapy, clinically manifested as cognitive impairment
-
Lancet Neurol Annual Inventory: Stroke of the 2022 Neurology Summary
Time of Update: 2023-02-03
The 2022 stroke clinical trial has many new answers and new questions. The journal Lancet Neurology conducts an annual inventory of stroke studies. Yimaitong compiles and arranges, please do not repri
-
JAMA sub-issue: Frequent use of social media affects young brains
Time of Update: 2023-02-03
Click "Read Original" to get more clinical dry goodsOn January 3, 2023, a new study published in JAMA Pediatrics concluded that the frequency with which adolescents browse on 3 social media platforms (Facebook, Instagram, Snapchat) is associated with longitudinal changes in functional brain development throughout adolescence.
-
Nature sub-journal: Spatial proteomics explores glioblastoma prognostic markers
Time of Update: 2023-02-03
Figure 1 ArticleExperimental methods: MALDI-MSI, label-free spatial proteomicsExperimental samples: 46 glioblastoma samplesSpatial area segmentation: red area, yellow area, blue areaAreas of interest
-
Refresh your awareness! Tau actually protects neurons in Alzheimer's patients
Time of Update: 2023-02-03
*For medical professionals onlyNeurofibrillary tangles caused by excessive phosphorylation of tau protein are one of the two main pathological features of Alzheimer's disease (AD), so excessive tau pr
-
Association of cumulative alcohol consumption in young people with stroke risk
Time of Update: 2023-02-03
commentsAlthough this analysis is based on self-reported alcohol consumption and may not be representative of the larger group of young people in Korea, it is important to have a better understanding of the relationship between alcohol consumption and stroke given the increasing per capita alcohol consumption globally.
-
Can aphasia after stroke get some recovery through singing?
Time of Update: 2023-02-03
Click "Read Original" to get more clinical dry goods*For medical professionals onlyIf you need it, you can give it a tryExecutive SummaryNew research published in Brain Communications on December 27, 2022, shows that singing can help people with aphasia after stroke to communicate and produce speech, even during the chronic phase of stroke.
-
Cell Yang Wuzhou et al. discovered the neural circuits that control the motor function of the hand
Time of Update: 2023-02-03
It also reveals the important role played by specific cerebral cortex-medullary nerve projection in controlling the aiming and manipulation functions of upper limb movement.
It also reveals the important role played by specific cerebral cortex-medullary nerve projection in controlling the aiming and manipulation functions of upper limb movement.
-
For the first time, human brain organoids were shown to establish functional connections and respond to external stimuli when implanted in mouse brains
Time of Update: 2023-02-03
The implanted human brain organoids respond to visual stimuli in the same way as surrounding tissue, and the researchers were able to observe this in real time over several months, thanks to an innovative experimental setup that combines a transparent graphene microelectrode array and two-photon imaging.
-
Master these 3 basic skills! Get a diagnosis of "mild cognitive impairment"
Time of Update: 2023-02-03
👇 Download the Decision Assistant App, the guide is free at any time ~ References: [1] Chinese expert consensus on the diagnosis and treatment of Alzheimer's pathogenic mild cognitive impairment 2021 ▼▼▼Click to read the original article to download the AppFor medical professionals onlyFor more guidelines for the diagnosis and treatment of common neurological diseases, go to the "Clinical Decision Assistant App"!
-
December neurology guidelines and consensus, one article included in the guideline consensus
Time of Update: 2023-02-03
cn/guideline/27616Recommended reading ☟☟☟January| February| March| April| May| June| July| August| September| October|November03Consensuson the diagnosis, treatment and management of cognitive impairment after noveland spread of coronavirus disease 2019 (COVID-19) (referred to as "new coronary pneumonia") around the world has had a huge impact on the physical and mental health of the people, especially the elderly, about 80% Patients infected with COVID have one or more long-term symptoms (level I evidence).
-
Nature| Wu Taihong et al. revealed the neural mechanism of pathogenic microorganisms to change host social behavior
Time of Update: 2023-02-03
On January 4, 2023, Dr. Wu Taihong and Dr. Ge Minghai and other researchers from the team of Professor Yun Zhang's team from the Department of Evolutionary Biology and Center for Brain Science at Harvard University published a report entitled Pathogenic bacteria modulate pheromone in the journal Nature Response to Promote Mating's long study using Caenorhabditis elegans as a model animal reveals the neural mechanism by which pathogenic microorganisms alter the social behavior of host nematodes.
