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New discoveries that allow paralyzed people to regain their ability to walk
Time of Update: 2023-01-05
In a study recently published in the journal Nature, an international team of researchers reported that patients paralyzed by spinal cord injury were able to recover some motor function after receiving targeted epidural electrical stimulation (EES) in areas that control leg movement.
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Dangerous genes that make Thor breathe
Time of Update: 2023-01-05
edu/news/alzheimers-risk-gene-undermines-insulation-brains-wiring#Image source:National Institute on Aging, NIH, Flickr, CC BY-NDJust last week, Chris Hamsworth, also known as "Thor," suddenly announced a temporary retirement.
edu/news/alzheimers-risk-gene-undermines-insulation-brains-wiring#Image source:National Institute on Aging, NIH, Flickr, CC BY-NDJust last week, Chris Hamsworth, also known as "Thor," suddenly announced a temporary retirement.
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Sudden syncope, how to deal with it? These 7 points to master
Time of Update: 2023-01-05
*For medical professionals only6 key points, collect it quickly!Syncope refers to a transient loss of consciousness caused by transient hypoperfusion of the brain, which is characterized by sudden, transient, transient and complete recovery on its own.
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The Psychol Med-Tang team explored the electrophysiological characteristics of sleep in 27 neuropsychiatric disorders
Time of Update: 2023-01-05
" In the article, the researchers explored and compared schizophrenia, bipolar disorder, generalized anxiety disorder, depression, obsessive-compulsive disorder, post-traumatic stress disorder, autism spectrum disorder, anorexia nervosa, stroke, epilepsy, Alzheimer's disease, Parkinson's disease, Huntington's disease, migraine, and traumatic brain injury through umbrella analysis27 The macroscopic and microscopic sleep structure patterns of neuropsychiatric diseases differed, and the results showed that different neuropsychiatric diseases had completely different overall changes in PSG.
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5 kinds of diagnosis of stroke pain in the elderly, understand in one article!
Time of Update: 2023-01-05
Central pain after stroke (CPSP)There are currently no uniform diagnostic criteria for CPSP, and diagnosis is based on the patient's history, physical examination, sensory tests, pain scores, and imaging.
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How is a spinal cord injury rehabilitated? 47 latest expert opinions in one article
Time of Update: 2023-01-05
At present, there is a lack of evidence-based medical guidelines for the rehabilitation of spinal cord injury in China, based on relevant scientific evidence, this guide proposes 47 clinical rehabilit
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Nature: Danqian Liu's team has made new progress in the study of REM sleep staging and cortical regulation
Time of Update: 2023-01-05
。 The study first found that the activity pattern of the cerebral cortex during REM sleep was significantly different from that during the awake phase, and that the RSC brain region was specifically highly active in REM sleep among the eleven cortical functional modules obtained by spatially independent component analysis(Figure A).
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Science: A big breakthrough! The Duyang team of Hong Kong Zhongda and others discovered a new type of non-addictive non-opioid painkiller
Time of Update: 2023-01-05
2A2A9087 and its analogues 7075 and PS75 are partial agonists of Gi, compared with known α2AAR agonists such as NorEpi, dex, and clon used in experiments, most of the screened new molecules can specifically activate the Gi, Go and Gz pathways, and the recruitment effect on β-inhibitory proteins is negligible at effective concentrations (except 0172), and there is no receptor internalization.
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What are new options for the treatment of generalized myasthenia gravis in adolescents? 2022 AANEM Essence Hot Review No. 4
Time of Update: 2023-01-05
Generalized myasthenia gravis (gMG) is a rare chronic autoimmune disease that can affect eye movement, swallowing, speech, movement, and respiratory function to varying degrees, severely impairing mob
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Nature | pattern regulation of V-ATPase in mammalian brains
Time of Update: 2023-01-05
Figure 2 Working modelIn general, the authors used V-ATPases proton pumps directly purified in mouse brains to unveil their different change patterns at the single-molecule level for the first time V-ATPases proton pumps in mammals can switch from active proton pump mode to inactive or proton leakage mode under pH gradient and ATP substrate adjustment (Figure 2), emphasizing the mechanism and biological importance of neurotransmitter delivery and proton pump mode switching.
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Alzheimer's Dement—A sword sharpened in ten years! Gu Baijun's team discovered congenital immune-related leukocyte surface antigen markers to help the early hematological diagnosis of Alzheimer's disease
Time of Update: 2023-01-05
Written by - Huangdao Lord, Li Yifan is responsible for editing - Wang Sizhen, Fang Yiyi editing - Xia Leaf Alzheimer's disease (AD) is a neurodegenerative disease characterized by cognitive impairmen
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New breakthrough in brain-computer interface: helping paralyzed patients control wheelchair free movement through thinking
Time of Update: 2023-01-05
Professor Gerwin Schalk, Director of TCCI's Frontiers Laboratory of Applied NeurotechnologyThe mind-controlled wheelchair is an assisted mobility solution based on brain-computer interface technology, especially for people with complete paralysis.
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How are antimicrobials used correctly? These 5 things to know!
Time of Update: 2023-01-05
Therapeutic medication For patients with clinical diagnosis of bacterial or fungal infection, the use of antibacterial drugs is therapeutic medicine 。 The most common in neurology is central nervous system (CNS) infection, which is an acute or chronic infection caused by various pathogens invading the brain parenchyma, membrane and blood vessels.
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Clearing the fog of encephalitis ---- eosinophilic meningitis
Time of Update: 2023-01-05
After 1 month of follow-up, the patient had no discomfort, no abnormalities in neurological examination, lumbar puncture cerebrospinal fluid pressure was 220mmH2 O, cerebrospinal fluid routine showed the number of white blood cells 16, cytology: lymphocytic inflammation, no eosinophils.
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Interview with Professor Xiao Nong and Professor Xu Kaishou: The Expert Consensus on Rehabilitation Management of Spinal Muscular Atrophy was released, leading the standardized SMA rehabilitation management
Time of Update: 2023-01-05
In this context, the Rehabilitation Group of the Pediatrics Branch of the Chinese Medical Association and the Physical Therapy Special Committee of the Chinese Association of Rehabilitation Medicine recently issued the Expert Consensus on the Rehabilitation Management of Spinal Muscular Atrophy to further standardize the rehabilitation assessment and treatment of SMA and give full play to the therapeutic role of rehabilitation combined with DMT drugs.
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Science—The New Gene Therapy! For disorders caused by abnormal activity of brain circuits in the case of epilepsy
Time of Update: 2023-01-05
, Science2022)Next, the authors asked whether cfos-KCNA1 gene therapy could achieve the purpose of reducing the frequency of epilepsy in a chronic epilepsy model。 The authors tested the combination in a KA (kainic acid)-induced mouse model of chronic epilepsy and used EcoG to record data on brain wave activity.
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Patent foramen ovale and migraine
Time of Update: 2023-01-05
The foramen ovale is generally closed in the first year after birth, if the foramen ovale is still not closed in children older than 3 years old, it is called patent foramen ovale, and 20%~25% of the foramen ovale in adults is not completely closed.
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The PNAS-Liu team revealed the important role of connexin hemichannels in alleviating neuroinflammation and overexcitability during the onset of temporal lobe epilepsy
Time of Update: 2023-01-05
Written by—Annie Guo, Junyu LiuResponsible editor—Wang Sizhen, Fang YiyiEditor—Summer LeafEpilepsy is one of the most common neurological disorders and manifests as spontaneous and recurrent seizures.
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PNAS: breaks through the blood-brain barrier, targets pathogenic RNA, treats ALS and dementia
Time of Update: 2023-01-05
Written byWang Cong EditorWang Duoyu TypesettingWater WritingAmyotrophic lateral sclerosis (ALS), also known as ALS, is one of the five terminal diseases recognized by the World Health Organization (W
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A 66-year-old female presents with progressive encephalopathy and bilateral hearing loss in clinical reasoning
Time of Update: 2023-01-05
Patients presenting with encephalopathy and acute/subacute hearing loss may be seen in Susac syndrome, intravascular lymphoma, primary central nervous system vasculitis (PACNS), and schwannomas.
Patients presenting with encephalopathy and acute/subacute hearing loss may be seen in Susac syndrome, intravascular lymphoma, primary central nervous system vasculitis (PACNS), and schwannomas.