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JNNP: Spinal cord injury and gray matter atrophy independently predict the clinical deterioration of well-defined multiple sclerosis, a 5-year, multicenter study
Time of Update: 2022-10-25
It is worth noting that 30% of relapsed MS and 70% of progressive MS have clinical deterioration: these rates are consistent with previous studies andOverall, spinal cord injury and cortical volume reduction contributed to a lesser extent in predicting the 5-year clinical prognosis of patients with multiple sclerosis.
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Neurology: biomarker of cerebrospinal fluid in Alzheimer's disease patients with α-synuclein pathology
Time of Update: 2022-10-25
The results showed that the α-SYN pathology associated with AD was associated with lower cerebrospinal fluid p-tau181, t-tau, and Ng levels, and could affect the diagnostic accuracy of AD patients.
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MRI performance of cerebral hematoma (detailed illustration)
Time of Update: 2022-10-25
In the hyperacute phase (< 24 hours), the hematoma is mainly composed of HBO2 in intact red blood cells, which can be divided into three stages on MR:(1) In stage I (0-3 hours), the hematoma showed low signal on T1-weighted image and high signal on T2-weighted image.
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Neurology: Prevalence and risk factors of chronic axonal polyneuropathy
Time of Update: 2022-10-25
Recently, a study published in Neurology investigated current and expected prevalence and investigated the (co-)incidence of risk factors in patients with chronic axonal polyneuropathy.
Recently, a study published in Neurology investigated current and expected prevalence and investigated the (co-)incidence of risk factors in patients with chronic axonal polyneuropathy.
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GWICC Live Registration On October 25~30, the 33rd Great Wall Cardiology Conference will meet you "in the cloud"!
Time of Update: 2022-10-25
Click on the link to register for free: Click on the link to register for free: Golden autumn is refreshing, dangui is fragrant, famous artists gather, meet the "Great Wall"!
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JAMA Neurol: Sartans reduce the risk of epilepsy in people with high blood pressure
Time of Update: 2022-10-25
Different antihypertensive drugs and epilepsyAmong hypertensive patients, the incidence of epilepsy is lowest in people treated with angiotensin receptor blockers, and this study is expected to be an important means of preventing epilepsy in hypertensive people.
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Immunity: dual developmental features of disease-associated microglia and disease-inflammation-associated macrophages in aging and neurodegeneration
Time of Update: 2022-10-25
Guide:The intracerebral macrophage population includes parenchymal microglia, border-associated macrophages, and recruited monocyte-derived cells. Together, these cells control brain development and h
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JNNP: Early predictor of multiple sclerosis disability in children
Time of Update: 2022-10-25
These factors include older age at onset of multiple sclerosis, more severe disability in the first year of onset, and the presence of pyramidal, visual, or cerebellar symptoms or signs, all of which predict a higher level of disability (quantified in MSSS and taking into account the time after the onset of multiple dementia).
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Key points of diagnosis and MRI signs of progressive supranuclear palsy
Time of Update: 2022-10-25
Horizontal axial T2-FLAIR MR imaging of the pons【Discussion】:T1WI in the middle of cranial MR in patients with PSP shows no signs of cortical atrophy often occurring in corticobasal degenerative diseases.
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Toxic encephalopathy of carbon monoxide
Time of Update: 2022-10-25
↑ Carbon monoxide toxic encephalopathy (a) Transverse axis T1WI: diffuse low signal with symmetrical distribution of bilateral cerebral white matter and basal ganglia area, narrowing of ventricular compression, shallow sulci and brain fission, and swelling of the brain gyrus, which is a manifestation of diffuse edema of brain tissue; (b) Transverse axis T2WI: uniform hyperintensity in the lesion area.
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European Radiology: IVIM using convolutional neural networks to predict HCC microvascular invasion
Time of Update: 2022-10-25
In addition, a recently published study that uses a deep convolutional network to extract the depth features of multiple b-value images in DWI can better predict the MVI of HCC.
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【ISC2016】Progress in non-vascular treatment of ischemic stroke
Time of Update: 2022-10-25
Take home message:The prehospital thrombolysis system of STEMO Mobile Stroke Emergency System has advantages over traditional hospital thrombolysis, which can significantly shorten the initiation time of thrombolysis therapy, thereby improving the safety and effectiveness of thrombolysis, and improving the functional outcome and quality of life of patients.
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Imaging patterns and differential diagnosis of toxic and metabolic brain diseases
Time of Update: 2022-10-25
Pathophysiology related knowledge:Schematic diagram of the types of cerebral edema Toxic and metabolic diseases that affect the central nervous system usually exhibit certain imaging features and distribution, and need to be closely clinically related to help confirm the diagnosis.
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Neurology: a meta-analysis of the relationship between mild cognitive impairment or dementia leading to subjective cognitive decline and Alzheimer's disease biomarkers
Time of Update: 2022-10-25
The search string includes terms: subjective cognitive decline, biomarkers, amyloid, tau protein, risk, Alzheimer's disease, mild cognitive impairment, and dementia.
The search string includes terms: subjective cognitive decline, biomarkers, amyloid, tau protein, risk, Alzheimer's disease, mild cognitive impairment, and dementia.
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Guidelines for secondary prevention of ischemic stroke and transient ischemic attack in China
Time of Update: 2022-10-25
Prediabetes and diabetesThe new guidelines recommend: For patients with ischemic stroke or TIA with diabetes, new hypoglycemic drugs that have been shown to be beneficial in reducing the risk of cardiovascular and cerebrovascular events (including stroke, myocardial infarction, and vascular death) can be considered (level II recommendation, level B evidence).
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European Radiology: How to more accurately predict the occurrence of recurrent ischemic cerebrovascular events in patients with intracranial atherosclerosis?
Time of Update: 2022-10-25
This study shows that high-resolution multicontrast MRI provides important diagnostic information for the prognostic assessment of patients with intracranial atherosclerotic disease, and that the enhancement rate and steepness of intracranial atherosclerotic plaque are independently associated with recurrent ischemic cerebrovascular events.
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Cell: Why do mosquitoes keep biting you? The preference of mosquitoes is related to the kind of smell you emit
Time of Update: 2022-10-25
On October 18, 2022, the team of Leslie Vosshall of The Rockefeller University in New York, USA, gave a presentation on Cell title: Differential mosquito attraction to humans is associated with skin-derived carboxylic acid levels.
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Science is a revolutionary breakthrough! Looking directly at the neural activity of the brain, this "simple" study will change brain science
Time of Update: 2022-10-25
Based on fMRI, the research team from South Korea has increased the temporal resolution of the detection to the millisecond level, so as to achieve direct imaging of neural activity in the brain.
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RESCUE study: Association between ASPECT scores and the effectiveness and safety of endovascular therapy in stroke patients with large-vessel occlusion
Time of Update: 2022-10-25
3285Association Between Alberta Stroke Program Early Computed Tomography Score and Efficacy and Safety Outcomes With Endovascular Therapy in Patients With Stroke From Large-Vessel Occlusion: A Secondary Analysis of the Recovery by Endovascular Salvage for Cerebral Ultra-acute Embolism—Japan Large Ischemic Core Trial (RESCUE-Japan LIMIT).
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senile cerebral atrophy or cerebral atrophy
Time of Update: 2022-10-25
can cause localized brain atrophy); Diffuse (senile brain, subcortical arteriosclerotic encephalopathy, multiple sclerosis, Alzhemeimer disease, Wilson's disease, cerebral hypoxia, poisoning, Parkinson disease, cerebellar atrophy, etc.
can cause localized brain atrophy); Diffuse (senile brain, subcortical arteriosclerotic encephalopathy, multiple sclerosis, Alzhemeimer disease, Wilson's disease, cerebral hypoxia, poisoning, Parkinson disease, cerebellar atrophy, etc.
