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The BMC Med-Dai Fangyin team has made important progress in constructing a Parkinson's syndrome model and evaluating efficacy by using silkworms
Time of Update: 2023-01-06
Written by - Song Jiangbo in charge - Wang Sizhen, Fang Yiyi edited - Wang RuhuaParkinson's disease (PD) is the most common neurodegenerative disease other than Alzheimer's disease, PD, in middle-aged
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Can you lose weight by smelling it? The latest research has found that food odor regulates fat metabolism
Time of Update: 2023-01-06
Food odor exposure causes lipid mobilization during fasting To elucidate metabolic changes in mice in the presence or absence of food odor stimuli, the researchers measured unesterified fatty acids (NEFA) serum levels, which are the main source of energy during fasting.
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How is frontotemporal degeneration diagnosed? Take a look at the latest Chinese expert consensus
Time of Update: 2023-01-06
Genetics and neuropathologyRecommendation 14: In view of the genetic characteristics of FTLD, it is recommended that patients with a clear family history of dementia, early-onset sporadic cases, special clinical phenotypes, and superimposed syndromes undergo genetic testing as soon as possible to assist diagnosis and subtype classification, which is conducive to early intervention (level I recommendation, level A evidence).
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Good intestines, good brains! Chinese scientists' latest discovery: This humble probiotic can change the trend of Parkinson's disease?
Time of Update: 2023-01-06
Bifidobacterium breve CCFM1067 alleviates MPTP-induced motor dysfunction in mice, and dopamine (DA) in the brain works in tandem with the glutamate system to control the body's motor and cognitive functions 。 The synthesis of DA is influenced by the rate-limiting enzyme tyrosine hydroxylase (TH), and motor symptoms of PD occur when TH levels fall below a certain threshold 。 Histopathological staining results showed that the intake of B.
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The GLIA-Baek Hyun-Sook/Frank Kirchhoff team found that a group of OPCs did not express Olig2, and that acute brain injury and learning activities promoted the formation of this group of cells
Time of Update: 2023-01-06
On October 29, 2022, Hyun-sook Baek and Frank Kirchhoff (Academician of the European Academy of Sciences) from the Department of Molecular Physiology at Saarland University in Germany were in the team A subset of OPCs do not express Olig2 during development which can be increased in the adult by brain injuries and complex motor was published in the GLIA publication learning".
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Focus on breathing and swallowing to see the new progress in the correction and treatment of spinal muscular atrophy
Time of Update: 2023-01-06
The Expert Consensus on Respiratory Management of Spinal Muscular Atrophy (2022 Edition) emphasizes that reasonable and effective respiratory management strategies are of great significance to stabilize the respiratory function of patients with SMA and reduce the incidence of respiratory related complications and disease mortality.
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"Nature" blockbuster: fight brain aging, treat Alzheimer's disease, this cell has a big effect
Time of Update: 2023-01-06
The Nature paper today shows a potential new direction in which immune cells around the brain can improve the brain's efficiency at removing waste, helping to reduce the aggregation of toxic proteins.
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"Seeing in pairs" layer by layer, what is the reason?
Time of Update: 2023-01-06
, did not support acute cerebrovascular disease and intracranial mass lesions; The patient began with drooping eyes and face, double vision, no abnormalities in the current electroneurography and negative neostigmine test→ which does not support myasthenia gravis; Glucose tolerance test does not support diabetes → so diabetic-related peripheral nerve damage is not considered →; At present, the possibility of painful ophthalmoplegia is considered to be high, and it is necessary to improve orbital imaging to further clarify.
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Ischemic stroke CISS classification and TOAST classification, clarified in one article
Time of Update: 2023-01-06
TOAST typing: cardioembolic high-risk, intermediate-risk embolic sources(Author's homemade)03 Small-artery occlusion lacunar (SAA):(1) Manifested as classic clinical lacunar syndrome with no evidence of cortical dysfunction;(2) a history of previous diabetes or hypertension is helpful in the diagnosis of this type;(3) Brain CT/MRI examination is normal, or there are lesions with a diameter of < 1.
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China's rare disease drugs have achieved another overseas success, and ACT001 has won the fourth major milestone - FDA orphan drug certification for diffuse midline glioma DMG
Time of Update: 2023-01-06
ACT001 is currently one of the few immunomodulators in the world that can cross the blood-brain barrier, and drug research and development focuses on brain tumors and brain inflammation, and has been approved for 12 clinical trials in China, the United States and Australia, including 4 phase 1 clinical trials, 7 1b/2a or phase 2 clinical trials, and 1 2b/3 phase clinic.
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China's rare disease drugs have achieved another overseas success, and ACT001 has won the fourth major milestone - FDA orphan drug certification for diffuse midline glioma DMG
Time of Update: 2023-01-06
ACT001 is currently one of the few immunomodulators in the world that can cross the blood-brain barrier, and drug research and development focuses on brain tumors and brain inflammation, and has been approved for 12 clinical trials in China, the United States and Australia, including 4 phase 1 clinical trials, 7 1b/2a or phase 2 clinical trials, and 1 2b/3 phase clinic.
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Summaptan, Zolmitriptan... One article masters the treatment of "cluster headache"
Time of Update: 2023-01-06
*For medical professionals onlyThese 5 things to know!Cluster headache (CH) is often clinically manifested as severe pain in the orbital, supraorbital, and/or temporal region of the strict unilateral
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Neurology—Liyuan Han's team systematically assesses the disease burden of stroke among young adults globally, regionally and nationally
Time of Update: 2023-01-06
Article conclusion and discussion, inspiration and prospectsAlthough age-standardized morbidity, mortality, and DALY rates of ischaemic stroke in young adults declined globally between 1990 and 2019, in low- and middle- and low-SDI regions such as North Africa, the Middle East and Southeast Asia, The burden of ischaemic stroke is still increasing.
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Is there also benefit in patients with seronegative myasthenia gravis? One of the 2022 AANEM Essentials Hot Review Series
Time of Update: 2023-01-06
GuideMG (myasthenia gravis) is an antibody-mediated autoimmune disease, acetylcholine receptor (AChR) antibodies are the most common pathogenic antibodies, AChR antibodies are present in about 85% of
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Academician comments The study of "Cell" of the Chinese Academy of Sciences revealed the mechanism of action of morphine and fentanyl, and the powerful analgesic got rid of addiction is one step closer
Time of Update: 2023-01-06
The cooperation of Xu Huaqiang/Zhuang Youwen, Xie Xin's team and Wang Mingwei's team from the Shanghai Institute of Materia Medica, Chinese Academy of Sciences revealed for the first time the mechanism of action of powerful analgesics fentanyl and morphine to recognize and activate μ opioid receptors (μOR), and systematically explored and deepened the understanding and understanding of the mechanism of μOR signaling regulation.
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Nature: Danqian Liu's team has made new progress in the study of REM sleep staging and cortical regulation
Time of Update: 2023-01-05
。 The study first found that the activity pattern of the cerebral cortex during REM sleep was significantly different from that during the awake phase, and that the RSC brain region was specifically highly active in REM sleep among the eleven cortical functional modules obtained by spatially independent component analysis(Figure A).
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This event will change a woman's brain and take up to two years to recover
Time of Update: 2023-01-05
Phone: 010-58302828-6808At present, 1130000+ doctors have followed and joined us A neuroscience study published November 22 in Nature Communications shows that the female brain leads to selective and significant changes in neural structure and neural network organization during pregnancy, which may lead to maternal behaviors during pregnancy and postpartum, such as nest building, snuggling heating, breastfeeding, physiological responses such as helping with bowel movements, and mother-infant attachment.
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5 kinds of diagnosis of stroke pain in the elderly, understand in one article!
Time of Update: 2023-01-05
Central pain after stroke (CPSP)There are currently no uniform diagnostic criteria for CPSP, and diagnosis is based on the patient's history, physical examination, sensory tests, pain scores, and imaging.
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How is a spinal cord injury rehabilitated? 47 latest expert opinions in one article
Time of Update: 2023-01-05
At present, there is a lack of evidence-based medical guidelines for the rehabilitation of spinal cord injury in China, based on relevant scientific evidence, this guide proposes 47 clinical rehabilit
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The Psychol Med-Tang team explored the electrophysiological characteristics of sleep in 27 neuropsychiatric disorders
Time of Update: 2023-01-05
" In the article, the researchers explored and compared schizophrenia, bipolar disorder, generalized anxiety disorder, depression, obsessive-compulsive disorder, post-traumatic stress disorder, autism spectrum disorder, anorexia nervosa, stroke, epilepsy, Alzheimer's disease, Parkinson's disease, Huntington's disease, migraine, and traumatic brain injury through umbrella analysis27 The macroscopic and microscopic sleep structure patterns of neuropsychiatric diseases differed, and the results showed that different neuropsychiatric diseases had completely different overall changes in PSG.
