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Don't doubt that your learning ability is sometimes really inferior to that of elementary school students! The latest research finds out why
Time of Update: 2023-01-06
Source: 123RFLooking at existing studies, Professor Watanabe noticed a problem: these studies only measured the level of GABA in children at a certain time, and did not consistently detect the trend of GABA before and after learning, which may lead to biased conclusions.
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Nature: Neuroscientist Lihui Cai reveals that APOE4 impairs the formation of myelin sheaths and causes cognitive dysfunction
Time of Update: 2023-01-06
1038/s41586-022-05439-wThe images in the article are from referencesthat this increase in cholesterol and lipid droplets was cell-specific: the increase was more pronouncedFigure 2: Expression of APOE4 in oligodendrocytes causes impaired myelination.
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Nature: Neuroscientist Lihui Cai reveals that APOE4 impairs the formation of myelin sheaths and causes cognitive dysfunction
Time of Update: 2023-01-06
1038/s41586-022-05439-wThe images in the article are from referencesthat this increase in cholesterol and lipid droplets was cell-specific: the increase was more pronouncedFigure 2: Expression of APOE4 in oligodendrocytes causes impaired myelination.
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"Nature" blockbuster: MIT cow Cai Lihui's team found for the first time that ApoE4 causes cholesterol to be deposited inside oligodendrocytes, intervening in cholesterol or becoming a new treatment for Alzheimer's disease
Time of Update: 2023-01-06
*For medical professionals onlyExcited heart, trembling hands, my idol Teacher Cai, sent "Nature" again!A few days ago, two phase 3 clinical trials of gantenerumab announced that they did not reach th
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Nature: Cancer cells show counter-common sense movement patterns! The Johns Hopkins team found that cancer cells migrate faster in high-viscosity extracellular fluid
Time of Update: 2023-01-06
In addition, there are some mechanisms that make cancer cells "slippery", even in high-viscosity extracellular fluid, they are not blocked, but run faster!Recently, a research team led by Professor Konstantinos Konstantopoulos of Johns Hopkins University found that the promotion of cell motility by high-viscosity extracellular fluid is achieved by regulating cytoskeleton, water channels and ion channels.
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Nature: Cai's team reveals how the Alzheimer's disease gene APOE4 damages the brain and finds potential therapies
Time of Update: 2023-01-06
Paper link: style="color: rgb(136, 136, 136);font-size: 12px;" _mstmutation="1" _istranslated="1"> open reprint, welcome to forward to the circle of friends and WeChat group Written by NagashiEditorWang DuoyuTypesettingWater writingAlzheimer's disease (AD), commonly known as "Alzheimer's disease", is a type of central nervous system degenerative disease that mainly occurs in the elderly and is characterized by progressive cognitive dysfunction and behavioral damage.
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Cell Mice with Williams syndrome have superior audio discrimination ability
Time of Update: 2023-01-06
In summary, the authors have superior audio discrimination ability through a mouse model of Williams syndrome, and this ability is caused by the downregulation of inhibitory interneuron Vipr1 in the auditory cortex.
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Cell: Why do we feel?
Time of Update: 2023-01-06
The work of cat-based organisms pointed out that postsynaptic dorsal column neurons (PSDCs) located in the central region of the dorsal horn show obvious mechanoceptive properties and have a projection area of maximum and high complexity 。 Of particular note is the presence of inhibitory and excitatory interneurons with different morphological and physiological traits in the dorsal horn, which can support mechanosensory signal output.
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The BMC Med-Dai Fangyin team has made important progress in constructing a Parkinson's syndrome model and evaluating efficacy by using silkworms
Time of Update: 2023-01-06
Written by - Song Jiangbo in charge - Wang Sizhen, Fang Yiyi edited - Wang RuhuaParkinson's disease (PD) is the most common neurodegenerative disease other than Alzheimer's disease, PD, in middle-aged
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"Nature" blockbuster: fight brain aging, treat Alzheimer's disease, this cell has a big effect
Time of Update: 2023-01-06
The Nature paper today shows a potential new direction in which immune cells around the brain can improve the brain's efficiency at removing waste, helping to reduce the aggregation of toxic proteins.
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Summaptan, Zolmitriptan... One article masters the treatment of "cluster headache"
Time of Update: 2023-01-06
*For medical professionals onlyThese 5 things to know!Cluster headache (CH) is often clinically manifested as severe pain in the orbital, supraorbital, and/or temporal region of the strict unilateral
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New breakthrough in brain-computer interface: Zhang Fulun's team helps paralyzed aphasia "speak" by decoding brain activity
Time of Update: 2023-01-06
75em;"> style="margin-bottom: 0px;text-align: left;margin-left: 8px;margin-right: 8px;line-height: normal;">Open reprint, welcome to forward to Moments and WeChat groups EditorWang Duoyu TypesettingShui Chengwen Neuroprosthesis is a device that replaces missing nervous system function and is expected to restore the ability to communicate in patients who are unable to speak or type due to paralysis.
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Thrombolytic "medicine" point showdown: Aquaman has a trident, can his strength be stronger than Superman?
Time of Update: 2023-01-06
Figure 8In other words, the efficacy of TNK in China is not inferior to rt-PA, and there is no statistical difference in safety, but the value of symptomatic intracranial hemorrhage, mortality, and PH2 type hemorrhage within 36 hours is higher than that of rt-PA.
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Thrombolytic "medicine" point showdown: Aquaman has a trident, can his strength be stronger than Superman?
Time of Update: 2023-01-06
Figure 8In other words, the efficacy of TNK in China is not inferior to rt-PA, and there is no statistical difference in safety, but the value of symptomatic intracranial hemorrhage, mortality, and PH2 type hemorrhage within 36 hours is higher than that of rt-PA.
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Sleep strengthens memory, but not the bad ones! Scientific studies have found that shorter naps do not increase fear-related memories
Time of Update: 2023-01-06
Pavlov and his research team from the Institute of Medical Psychology and Behavioral Neurobiology at the University of Tübingen made healthy subjects receive conditioned fear memory, compared the subjects' response to re-exposure to fear conditions after a 2-hour nap or corresponding waking time, and found that sleep did not enhance the subjects' fear-response behavior, nor did it affect brain event-related potentials (ERP); Fear memories are gradually consolidated over time and are independent of whether or not to nap.
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How to distinguish "peripheral vertigo" from "central vertigo"?
Time of Update: 2023-01-06
Come to the "doctor's station" and take a look 👇Acute vestibular syndrome = acute onset of vertigo + severe and persistent symptoms + vertigo worsening due to change in head position + visible nystagmus visible by gaze.
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How to distinguish "peripheral vertigo" from "central vertigo"?
Time of Update: 2023-01-06
Come to the "doctor's station" and take a look 👇Acute vestibular syndrome = acute onset of vertigo + severe and persistent symptoms + vertigo worsening due to change in head position + visible nystagmus visible by gaze.
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Chiropractic Rejuvenation and Concerted Efforts Review of the 1st Adult Spinal Muscular Atrophy Summit Forum
Time of Update: 2023-01-06
Professor Zhang Min: Real-world studies enrich the evidence for the treatment of SMA in adults, and DMT drugs bring significant benefitsProfessor Zhang Min, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology➤ Several pivotal studies confirm the efficacy and safety of nocinaxen in children and adultsMultiple natural history studies have found progressive decline in functions in patients with SMA.
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Fighting insomnia is just one step! Studies have shown that the thicker the quilt, the more melatonin is secreted...
Time of Update: 2023-01-06
Research process 02 02For the study, researchers selected 26 young, healthy participants, including 15 men and 11 women, to investigate whether the use of a thick quilt (about 12% of body weight) before bed resulted in higher concentrations of melatonin and oxytocin in saliva than light quilt (about 2.
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Childhood exposure to lead has been linked to cognitive decline in old age |Science Advances
Time of Update: 2023-01-06
Welcome to follow Science's official public account, click "Read Original" below to access open access papers Light up for this issue of Science AdvancesClick on the blue text above to follow usAccording to a recent analysis of data from the Health and Retirement Study (HRS) based in the United States, exposure to lead-contaminated drinking water in childhood may be associated with poorer baseline cognitive function in old age, but not with accelerated rates of cognitive decay.
