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Vertigo time · Stage 2a Bedside examination of patients with dizziness/vertigo
Time of Update: 2023-01-06
Left eye trochlear nerve palsyOTR abnormalityReferences and image sources: Past recommendations:Vertigo time · Issue 1 | History of patients with vertigo/vestibular diseaseAuthors: Ling Xia, Wu Yuexia, Zhao Tongtong, Zhao Guiping, Wang Chaoxia, Yang XuUnit: Department of Neurology, Peking University First Hospital, Department of Neurology, Peking University School of Aerospace Clinical MedicineVertigo/vestibular disease has a high incidence, complex etiology, and multidisciplinary knowledge.
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Vertigo time · Stage 2a Bedside examination of patients with dizziness/vertigo
Time of Update: 2023-01-06
Left eye trochlear nerve palsyOTR abnormalityReferences and image sources: Past recommendations:Vertigo time · Issue 1 | History of patients with vertigo/vestibular diseaseAuthors: Ling Xia, Wu Yuexia, Zhao Tongtong, Zhao Guiping, Wang Chaoxia, Yang XuUnit: Department of Neurology, Peking University First Hospital, Department of Neurology, Peking University School of Aerospace Clinical MedicineVertigo/vestibular disease has a high incidence, complex etiology, and multidisciplinary knowledge.
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Chiropractic Rejuvenation and Concerted Efforts Review of the 1st Adult Spinal Muscular Atrophy Summit Forum
Time of Update: 2023-01-06
Professor Zhang Min: Real-world studies enrich the evidence for the treatment of SMA in adults, and DMT drugs bring significant benefitsProfessor Zhang Min, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology➤ Several pivotal studies confirm the efficacy and safety of nocinaxen in children and adultsMultiple natural history studies have found progressive decline in functions in patients with SMA.
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Primary VS secondary trigeminal neuralgia, what is the difference?
Time of Update: 2023-01-06
Download the Decision Assistant App, the guide is free at any time~References:[1] Chinese expert consensus on the diagnosis and treatment of trigeminal neuralgia▼▼▼Click to read the original article to download the App*For medical professionals onlyScientific response to the "world's first pain"!
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Nature Medicine: Cognition is normal, but Aβ and Tau PET are both positive, and the risk of cognitive decline soars 18 times in the next 3-5 years!
Time of Update: 2023-01-06
The study found that the group with both Aβ and tau positive (A+T+) but cognitively normal after PET verification had a 19-fold increase in the risk of progressing to MCI within 3~5 years compared with the negative group (A-T-)++-[1]!
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Cell Mice with Williams syndrome have superior audio discrimination ability
Time of Update: 2023-01-06
In summary, the authors have superior audio discrimination ability through a mouse model of Williams syndrome, and this ability is caused by the downregulation of inhibitory interneuron Vipr1 in the auditory cortex.
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Nature: Cancer cells show counter-common sense movement patterns! The Johns Hopkins team found that cancer cells migrate faster in high-viscosity extracellular fluid
Time of Update: 2023-01-06
In addition, there are some mechanisms that make cancer cells "slippery", even in high-viscosity extracellular fluid, they are not blocked, but run faster!Recently, a research team led by Professor Konstantinos Konstantopoulos of Johns Hopkins University found that the promotion of cell motility by high-viscosity extracellular fluid is achieved by regulating cytoskeleton, water channels and ion channels.
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J Neurol—melanin-sensitive magnetic resonance imaging studies reveal blue spot degeneration and cerebellar volume changes in patients with essential tremor
Time of Update: 2023-01-06
published titles in the Journal of Neurology The research paper "Locus coeruleus degeneration and cerebellar gray matter changes in essential tremor" found that the blue spot signal value (the) in ET patients found that the blue spot signal value (the) in ET patients contrast-to-noise ratio of LC (CNRLC) is lower than normal control (HC).
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Neuron Army Medical University Niu Jianqin/Sun Yat-sen University Yi Chen Ju et al. discovered a new mechanism for the regulation of perivascular migration of oligodendrocytes precursor cells
Time of Update: 2023-01-06
Original link: 00991-6—END—The content is [iNature]iNatureOligodendroid precursor cells (OPCs) undergo extensive and coordinated migration in the developing central nervous system, utilizing pre-formed scaffolds of developed blood vessels as the physical matrix for migration.
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Nature: Neuroscientist Lihui Cai reveals that APOE4 impairs the formation of myelin sheaths and causes cognitive dysfunction
Time of Update: 2023-01-06
1038/s41586-022-05439-wThe images in the article are from referencesthat this increase in cholesterol and lipid droplets was cell-specific: the increase was more pronouncedFigure 2: Expression of APOE4 in oligodendrocytes causes impaired myelination.
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Nature: Neuroscientist Lihui Cai reveals that APOE4 impairs the formation of myelin sheaths and causes cognitive dysfunction
Time of Update: 2023-01-06
1038/s41586-022-05439-wThe images in the article are from referencesthat this increase in cholesterol and lipid droplets was cell-specific: the increase was more pronouncedFigure 2: Expression of APOE4 in oligodendrocytes causes impaired myelination.
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Focus on breathing and swallowing to see the new progress in the correction and treatment of spinal muscular atrophy
Time of Update: 2023-01-06
The Expert Consensus on Respiratory Management of Spinal Muscular Atrophy (2022 Edition) emphasizes that reasonable and effective respiratory management strategies are of great significance to stabilize the respiratory function of patients with SMA and reduce the incidence of respiratory related complications and disease mortality.
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What are the characteristics of pain in the acute phase of shingles?
Time of Update: 2023-01-06
Download the Decision Assistant App and check it anytime, anywhere~Click "Read Original" to get the guidelines*For medical professionals onlyDiagnose and treat big and small problems, see what the guidelines say What are the diagnostic criteria for major diseases?
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What are the characteristics of pain in the acute phase of shingles?
Time of Update: 2023-01-06
Download the Decision Assistant App and check it anytime, anywhere~Click "Read Original" to get the guidelines*For medical professionals onlyDiagnose and treat big and small problems, see what the guidelines say What are the diagnostic criteria for major diseases?
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"Nature" blockbuster: fight brain aging, treat Alzheimer's disease, this cell has a big effect
Time of Update: 2023-01-06
The Nature paper today shows a potential new direction in which immune cells around the brain can improve the brain's efficiency at removing waste, helping to reduce the aggregation of toxic proteins.
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Academician comments The study of "Cell" of the Chinese Academy of Sciences revealed the mechanism of action of morphine and fentanyl, and the powerful analgesic got rid of addiction is one step closer
Time of Update: 2023-01-06
The cooperation of Xu Huaqiang/Zhuang Youwen, Xie Xin's team and Wang Mingwei's team from the Shanghai Institute of Materia Medica, Chinese Academy of Sciences revealed for the first time the mechanism of action of powerful analgesics fentanyl and morphine to recognize and activate μ opioid receptors (μOR), and systematically explored and deepened the understanding and understanding of the mechanism of μOR signaling regulation.
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Thrombolytic "medicine" point showdown: Aquaman has a trident, can his strength be stronger than Superman?
Time of Update: 2023-01-06
Figure 8In other words, the efficacy of TNK in China is not inferior to rt-PA, and there is no statistical difference in safety, but the value of symptomatic intracranial hemorrhage, mortality, and PH2 type hemorrhage within 36 hours is higher than that of rt-PA.
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Thrombolytic "medicine" point showdown: Aquaman has a trident, can his strength be stronger than Superman?
Time of Update: 2023-01-06
Figure 8In other words, the efficacy of TNK in China is not inferior to rt-PA, and there is no statistical difference in safety, but the value of symptomatic intracranial hemorrhage, mortality, and PH2 type hemorrhage within 36 hours is higher than that of rt-PA.
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Cell: Why do we feel?
Time of Update: 2023-01-06
The work of cat-based organisms pointed out that postsynaptic dorsal column neurons (PSDCs) located in the central region of the dorsal horn show obvious mechanoceptive properties and have a projection area of maximum and high complexity 。 Of particular note is the presence of inhibitory and excitatory interneurons with different morphological and physiological traits in the dorsal horn, which can support mechanosensory signal output.
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The INT J CANCER-XIA/PENG LIANG TEAM REVEALED THAT GLIOMA CELL-NEURON SYNAPTIC CONNECTIONS ARE IMPORTANT FACTORS AFFECTING THE SPATIAL PATHOGENESIS OF CELL TUMORS
Time of Update: 2023-01-06
The authors first constructed GBM and LGG by using the patient image data of the Department of Neurosurgery of Harbin Medical University Cancer Hospital and the public resources of the imaging database The Cancer Imaging Archive and spatial probability distribution plots of gliomas of different molecular subtypes (Figure 1).