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Nature: Allowed 9 paralyzed patients to regain the ability to walk, and now the cause is finally understood
Time of Update: 2023-01-06
Link to Grégoire Courtine (right) and Jocelyne Bloch (left): style="caret-color: rgb(255, 0, 0);font-family: , "Microsoft YaHei", sans-serif;color: rgb(136, 136, 136);font-size: 12px;letter-spacing: normal;" _mstmutation="1" _istranslated="1"> open reprint, welcome to forward to Moments and WeChat groups Written byTwo pearsSourceLilac AcademicAs early as 30 years ago, preclinical and clinical studies showed that epidural electrical stimulation (ESS) on the lumbosacral spinal cord restored the ability to walk in patients with spinal cord injury.
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How does the gut microbiota control brain and social behavior?
Time of Update: 2023-01-06
Microbiota promotes forebrain microglial abundance and inhibits vTely321 neurite density Microglia are brain resident immune cells that regulate neurite growth and pruning, and the researchers hypothesize that the microbiota may inhibit the complications of vTely321 dendrites through microglia.
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How does the gut microbiota control brain and social behavior?
Time of Update: 2023-01-06
Microbiota promotes forebrain microglial abundance and inhibits vTely321 neurite density Microglia are brain resident immune cells that regulate neurite growth and pruning, and the researchers hypothesize that the microbiota may inhibit the complications of vTely321 dendrites through microglia.
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Cell: Why are mosquitoes chasing and biting you? Scientists have revealed that the higher the expression of carboxylic acids in the skin, the more attractive mosquitoes are
Time of Update: 2023-01-06
1038/s41586-022-05328-2The images in the article are from referencesFigure 1: Different human individuals of mosquitoes show obvious preference2Mosquito highly attractive people have increased levels of carboxylic acids in the skin odorMosquitoes perceive olfactory information through two types of odor-gated ion channels, odor receptors (OR) and ionic receptors (IR).
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Express alleviates the symptoms of Parkinson's disease, and the new treatment is expected to be approved in the first half of next year
Time of Update: 2023-01-06
▲If you have any business needs, please press and hold to scan the QR code above, or▎WuXi AppTec content team editorToday, Amneal Pharmaceuticals announced that the U.
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Nature's blockbuster breakthrough! For the first time, the neural mechanism of striatal dopamine adenosine affecting PKA activity was revealed, which helped Parkinson's drug research new strategies
Time of Update: 2023-01-06
1038/s41586-022-05407-4 In vivo PKA imaging revealed the cell-specific regulation of PKA by DA The author injected adeno-associated virus (AAV) (a PKA probe) into DLS in D1R-Cre or Adora2a-cre mice, implanted GRIN lens, and added two-photon fluorescence lifetime microscopy (2pFLIM) technology to achieve in vivo imaging of dSPN or iSPN PKA for the first time , PKA activity in SPN under basal conditions was successfully discovered.
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Nature Zhong's team discovered a "brake" mechanism for the brain's control of motion
Time of Update: 2023-01-06
On November 9, 2022, the team of Haining Zhong at the Vollum Institute of Health and Science University of Oregon published an article in Nature magazine, Locomotion activates PKA through dopamine and adenosine in striatal neurons , revealing a new "brake" mechanism in motor control in the striatum of the brain, opening new avenues for the treatment of Parkinson's and other diseases associated with the striatum.
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Primary VS secondary trigeminal neuralgia, what is the difference?
Time of Update: 2023-01-06
Download the Decision Assistant App, the guide is free at any time~References:[1] Chinese expert consensus on the diagnosis and treatment of trigeminal neuralgia▼▼▼Click to read the original article to download the App*For medical professionals onlyScientific response to the "world's first pain"!
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Distal ischemia preconditioning intervention after moderate ischaemic stroke
Time of Update: 2023-01-06
commentsGiven that 6% of patients were rapidly excluded after randomization, that results had not been reported by the primary intention-to-treat analysis pre-specified in the statistical analysis plan, and that the trial was open-label rather than sham designed, this is particularly concerning because of the importance of proof-of-principle trials evaluating novel therapies for stroke.
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What are the characteristics of pain in the acute phase of shingles?
Time of Update: 2023-01-06
Download the Decision Assistant App and check it anytime, anywhere~Click "Read Original" to get the guidelines*For medical professionals onlyDiagnose and treat big and small problems, see what the guidelines say What are the diagnostic criteria for major diseases?
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What are the characteristics of pain in the acute phase of shingles?
Time of Update: 2023-01-06
Download the Decision Assistant App and check it anytime, anywhere~Click "Read Original" to get the guidelines*For medical professionals onlyDiagnose and treat big and small problems, see what the guidelines say What are the diagnostic criteria for major diseases?
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Vertigo time · Stage 2a Bedside examination of patients with dizziness/vertigo
Time of Update: 2023-01-06
Left eye trochlear nerve palsyOTR abnormalityReferences and image sources: Past recommendations:Vertigo time · Issue 1 | History of patients with vertigo/vestibular diseaseAuthors: Ling Xia, Wu Yuexia, Zhao Tongtong, Zhao Guiping, Wang Chaoxia, Yang XuUnit: Department of Neurology, Peking University First Hospital, Department of Neurology, Peking University School of Aerospace Clinical MedicineVertigo/vestibular disease has a high incidence, complex etiology, and multidisciplinary knowledge.
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Vertigo time · Stage 2a Bedside examination of patients with dizziness/vertigo
Time of Update: 2023-01-06
Left eye trochlear nerve palsyOTR abnormalityReferences and image sources: Past recommendations:Vertigo time · Issue 1 | History of patients with vertigo/vestibular diseaseAuthors: Ling Xia, Wu Yuexia, Zhao Tongtong, Zhao Guiping, Wang Chaoxia, Yang XuUnit: Department of Neurology, Peking University First Hospital, Department of Neurology, Peking University School of Aerospace Clinical MedicineVertigo/vestibular disease has a high incidence, complex etiology, and multidisciplinary knowledge.
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eLife—Wang Liping group discovered neural computing of causal inference in the frontal parietal loop of macaques
Time of Update: 2023-01-06
Written by Qi Guangyao - Wang Sizhen, Fang Yiyi edited by Xia YeIn daily life, we often receive a variety of sensory information. Properly integrating multisensory information can help us respond fast
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eLife—Wang Liping group discovered neural computing of causal inference in the frontal parietal loop of macaques
Time of Update: 2023-01-06
Written by Qi Guangyao - Wang Sizhen, Fang Yiyi edited by Xia YeIn daily life, we often receive a variety of sensory information. Properly integrating multisensory information can help us respond fast
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Illustrative Through writing and drawing, you can easily identify various tremors
Time of Update: 2023-01-06
Through the drawing of the straight line, it can be seen that the left hand (main) vertical line has 18 tremors in 2 seconds, with an estimated frequency of 9Hz. C: In this example, a plot drawn by a patient with severe essential tremor shows a clear large tremor in the unidirectional axis, with fairly regular amplitude and frequency, and bilateral symmetry.
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Risk identification, cause analysis, treatment steps of cerebral herniation, this article explains clearly!
Time of Update: 2023-01-06
Come to the "doctor's station" and take a look 👇*For medical professionals onlyThis article analyzes cerebral herniation from multiple perspectives, such as clinical manifestations, risk identification, etiology analysis, and treatment steps.
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There are so many vertigo terms, how to distinguish them?
Time of Update: 2023-01-06
Come to the "doctor's station" and take a look 👇Vertigoof self-movement that is distorted during normal head movement, in short, the feeling that oneself is moving(not actually moving),which is different from external vertigo, which refers to the "external" visual motor sensation or oscilloscope[vestibular visual symptoms, in short, seeing something moving (in fact neither you nor the thing moving)].
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Changes in consciousness after a fall in patients with spinal cord injury Clinical reasoning
Time of Update: 2023-01-06
What are the next steps for the assessment?Part IIIPunctate diffusion restriction and microbleeding suggest that the lesion involves small blood vessels, and differential diagnoses include vasculitis, microangiopathy, or embolism.
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Nature: Neuroscientist Lihui Cai reveals that APOE4 impairs the formation of myelin sheaths and causes cognitive dysfunction
Time of Update: 2023-01-06
1038/s41586-022-05439-wThe images in the article are from referencesthat this increase in cholesterol and lipid droplets was cell-specific: the increase was more pronouncedFigure 2: Expression of APOE4 in oligodendrocytes causes impaired myelination.
