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Sleep strengthens memory, but not the bad ones! Scientific studies have found that shorter naps do not increase fear-related memories
Time of Update: 2023-01-06
Pavlov and his research team from the Institute of Medical Psychology and Behavioral Neurobiology at the University of Tübingen made healthy subjects receive conditioned fear memory, compared the subjects' response to re-exposure to fear conditions after a 2-hour nap or corresponding waking time, and found that sleep did not enhance the subjects' fear-response behavior, nor did it affect brain event-related potentials (ERP); Fear memories are gradually consolidated over time and are independent of whether or not to nap.
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Fighting insomnia is just one step! Studies have shown that the thicker the quilt, the more melatonin is secreted...
Time of Update: 2023-01-06
Research process 02 02For the study, researchers selected 26 young, healthy participants, including 15 men and 11 women, to investigate whether the use of a thick quilt (about 12% of body weight) before bed resulted in higher concentrations of melatonin and oxytocin in saliva than light quilt (about 2.
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Cell Mice with Williams syndrome have superior audio discrimination ability
Time of Update: 2023-01-06
In summary, the authors have superior audio discrimination ability through a mouse model of Williams syndrome, and this ability is caused by the downregulation of inhibitory interneuron Vipr1 in the auditory cortex.
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Express alleviates the symptoms of Parkinson's disease, and the new treatment is expected to be approved in the first half of next year
Time of Update: 2023-01-06
▲If you have any business needs, please press and hold to scan the QR code above, or▎WuXi AppTec content team editorToday, Amneal Pharmaceuticals announced that the U.
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For the first time, the journal Nature found that the abnormal protein construction of Parkinson's disease is inseparable from this molecule
Time of Update: 2023-01-06
▎ WuXi AppTec content team editor Parkinson's disease currently plagues more than 6 million patients worldwide, and the distinctive feature of the disease is abnormal α-synuclein clumps in the brain 。
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Dev Cell—Tian Ye's team found that the GPCR signaling pathway coordinates the body's mitochondrial stress response in a pair of sensory neurons
Time of Update: 2023-01-06
Written by Liu Yangli, edited by Zhou Jun -- Wang Sizhen, edited by Fang Yiyi -- Xia YeThe nervous system plays an important role in sensing and coordinating the body's stress response. When the mitoc
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Yu Shuyan's team at Shandong University revealed the molecular mechanism of neuronal intracellular PH imbalance inducing depression
Time of Update: 2023-01-06
Stress-induced reduction of Na+/H+ exchanger isoform 1promotes maladaptation of neuroplasticityand exacerbates depressive behaviors The images in the article are from referencesClick on the blue word to follow usDue to proteins involved in regulating neuronal excitability, the brain is very sensitive to changes in pH, and effective synaptic transmission depends critically on proper pH.
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Yu Shuyan's team at Shandong University revealed the molecular mechanism of neuronal intracellular PH imbalance inducing depression
Time of Update: 2023-01-06
Stress-induced reduction of Na+/H+ exchanger isoform 1promotes maladaptation of neuroplasticityand exacerbates depressive behaviors The images in the article are from referencesClick on the blue word to follow usDue to proteins involved in regulating neuronal excitability, the brain is very sensitive to changes in pH, and effective synaptic transmission depends critically on proper pH.
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AD: The Shen Yong team of the First Affiliated Hospital of the University of Science and Technology of China proposed a new standard for the diagnosis of Alzheimer's disease blood suitable for Chinese
Time of Update: 2023-01-06
*For medical professionals onlyAlzheimer's disease (AD) is the most common neurodegenerative disease in middle-aged and elderly people, mainly manifested as progressive cognitive decline, and there is
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AD: The Shen Yong team of the First Affiliated Hospital of the University of Science and Technology of China proposed a new standard for the diagnosis of Alzheimer's disease blood suitable for Chinese
Time of Update: 2023-01-06
*For medical professionals onlyAlzheimer's disease (AD) is the most common neurodegenerative disease in middle-aged and elderly people, mainly manifested as progressive cognitive decline, and there is
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The INT J CANCER-XIA/PENG LIANG TEAM REVEALED THAT GLIOMA CELL-NEURON SYNAPTIC CONNECTIONS ARE IMPORTANT FACTORS AFFECTING THE SPATIAL PATHOGENESIS OF CELL TUMORS
Time of Update: 2023-01-06
The authors first constructed GBM and LGG by using the patient image data of the Department of Neurosurgery of Harbin Medical University Cancer Hospital and the public resources of the imaging database The Cancer Imaging Archive and spatial probability distribution plots of gliomas of different molecular subtypes (Figure 1).
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Neuron Army Medical University Niu Jianqin/Sun Yat-sen University Yi Chen Ju et al. discovered a new mechanism for the regulation of perivascular migration of oligodendrocytes precursor cells
Time of Update: 2023-01-06
Original link: 00991-6—END—The content is [iNature]iNatureOligodendroid precursor cells (OPCs) undergo extensive and coordinated migration in the developing central nervous system, utilizing pre-formed scaffolds of developed blood vessels as the physical matrix for migration.
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Although "late", Chinese and American experts gathered in Chengdu to discuss the experience of diagnosis and treatment of adult tardive dyskinesia
Time of Update: 2023-01-06
On October 29, 2022, the first Deuterium Tetraphenazine China and West International Summit Forum was successfully held in Chengdu, where many experts in psychiatry and neurology at home and abroad shared their experience in TD and HD treatment, opening up a smooth life for more patients.
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Cell: Why are mosquitoes chasing and biting you? Scientists have revealed that the higher the expression of carboxylic acids in the skin, the more attractive mosquitoes are
Time of Update: 2023-01-06
1038/s41586-022-05328-2The images in the article are from referencesFigure 1: Different human individuals of mosquitoes show obvious preference2Mosquito highly attractive people have increased levels of carboxylic acids in the skin odorMosquitoes perceive olfactory information through two types of odor-gated ion channels, odor receptors (OR) and ionic receptors (IR).
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Nature's blockbuster breakthrough! For the first time, the neural mechanism of striatal dopamine adenosine affecting PKA activity was revealed, which helped Parkinson's drug research new strategies
Time of Update: 2023-01-06
1038/s41586-022-05407-4 In vivo PKA imaging revealed the cell-specific regulation of PKA by DA The author injected adeno-associated virus (AAV) (a PKA probe) into DLS in D1R-Cre or Adora2a-cre mice, implanted GRIN lens, and added two-photon fluorescence lifetime microscopy (2pFLIM) technology to achieve in vivo imaging of dSPN or iSPN PKA for the first time , PKA activity in SPN under basal conditions was successfully discovered.
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"Nature" sub-journal: Professor Li Bo's team in Cold Spring Port Laboratory found a neural pathway that "can't control the mouth"
Time of Update: 2023-01-06
Recently, Professor Li Bo's team of Cold Spring Harbor Laboratory in the United States published a study on neurons in the amygdala driving hedonic eating in the journal Nature Neuroscience [4], revealing that IPAC-NTS neurons in the amygdala are key nodes in promoting hedonic eating and energy metabolism, which is expected to provide new treatment strategies for the prevention and treatment of obesity.
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"Nature" sub-journal: Professor Li Bo's team in Cold Spring Port Laboratory found a neural pathway that "can't control the mouth"
Time of Update: 2023-01-06
Recently, Professor Li Bo's team of Cold Spring Harbor Laboratory in the United States published a study on neurons in the amygdala driving hedonic eating in the journal Nature Neuroscience [4], revealing that IPAC-NTS neurons in the amygdala are key nodes in promoting hedonic eating and energy metabolism, which is expected to provide new treatment strategies for the prevention and treatment of obesity.
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CNS Neuroscience & Therapeutics: Butylphthalide combined with recanalization is safe and effective
Time of Update: 2023-01-06
Research methodsThis study was analyzed using data from three EVT studies on LVO leading to AIS patients, including: the BASILAR study (coverage 47 A national registry study of acute basilar artery occlusion in stroke centres), the DEVT study (a multicentre open-label randomized controlled trial covering anterior circulation LVOs in 33 stroke centres), and one study on national LVOs A multicenter study of the safety and efficacy of endovascular therapy for AIS.
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CNS Neuroscience & Therapeutics: Butylphthalide combined with recanalization is safe and effective
Time of Update: 2023-01-06
Research methodsThis study was analyzed using data from three EVT studies on LVO leading to AIS patients, including: the BASILAR study (coverage 47 A national registry study of acute basilar artery occlusion in stroke centres), the DEVT study (a multicentre open-label randomized controlled trial covering anterior circulation LVOs in 33 stroke centres), and one study on national LVOs A multicenter study of the safety and efficacy of endovascular therapy for AIS.
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Nature Zhong's team discovered a "brake" mechanism for the brain's control of motion
Time of Update: 2023-01-06
On November 9, 2022, the team of Haining Zhong at the Vollum Institute of Health and Science University of Oregon published an article in Nature magazine, Locomotion activates PKA through dopamine and adenosine in striatal neurons , revealing a new "brake" mechanism in motor control in the striatum of the brain, opening new avenues for the treatment of Parkinson's and other diseases associated with the striatum.
