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European Radiology: Applications of radiomics in identifying Parkinson's disease
Time of Update: 2022-11-04
(a) Comparison of PD and NC in the Huashan cohort, and (b) Comparison of PD and NC in the Wuxi cohortIn this study, a DLR method was developed to diagnose PD and PD subgroups, and the proposed model has significantly improved diagnostic performance compared with existing methods, providing a practical imaging method for computer-aided diagnosis of PD.
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Ann Neurol: Correlation between pathological spread of Alzheimer's disease and activation of microglia
Time of Update: 2022-11-04
For comparison, Figure 1B shows the mean TSPO-PET SUVR binding pattern within the AD group and evaluates the association of functional and structural connections with the covariance of TSPO-PET tracer uptake in subsequent regression analysis.
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[Image Note] Reversible posterior encephalopathy syndrome (PRES)
Time of Update: 2022-11-04
CT findings: lack of specificity, mostly manifested as bilateral parietal occipital lobes symmetrical patchy low-density opacities, no mass effect.
CT findings: lack of specificity, mostly manifested as bilateral parietal occipital lobes symmetrical patchy low-density opacities, no mass effect.
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Combining AI with microelectronics, Chinese scholars have created neuroimplants to fight brain diseases
Time of Update: 2022-11-04
Open reprint welcome to forward to Moments and WeChat groups Written byWang CongEditorWang Duoyu TypesettingShui Chengwen Neural Implants can help treat brain diseases such as Parkinson's disease and epilepsy by directly regulating abnormal neuronal activity.
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【PHILIPS 1 case per day】1 case of subacute combined degeneration
Time of Update: 2022-11-04
Key points of diagnosis:MRI STIR and T2WI images show enhanced symmetry of the posterior cord (relatively rare lateral cords), and the "inverted V" sign is visible in the horizontal plane;There may be a mild mass effect and contrast signal enhancement.
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Neurology: Quantitative diffusion-weighted magnetic resonance neuroimaging in relation to cardiac arrest outcomes in children
Time of Update: 2022-11-04
Because ADCs decline exponentially with age, a study published in Neurology established an association of 1) having > 10% of brain tissue below the new age-dependent ADC threshold, and 2) whole-brain mean ADCs and adverse outcomes.
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New study from Beijing Tiantan Hospital: Efficacy and safety effects of renal function on different bispecific antibody treatment strategies in patients with acute ischemic cerebrovascular disease
Time of Update: 2022-11-04
In this study, 6,378 subjects were divided into three groups: normal renal function, mild renal function decline, and moderate to severe renal function decline according to glomerular filtration rate 。 The results of the study showed that for the outcome of stroke recurrence, bispecific antibody therapy had a certain interaction with renal function status, and ticagrelor-aspirin bispecific antibody treatment could effectively reduce the stroke recurrence rate in patients with normal renal function compared with clopidogrel - aspirin treatment (HR, 0.
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JNNP: Efficacy and safety of natalizumab during pregnancy, Italian cohort of women with multiple sclerosis
Time of Update: 2022-11-04
Maternal clinical and radiological outcomes, as well as obstetric and fetal outcomes, were collected retrospectively and compared between groups (NO_EXP not pregnant, SHORT_EXP pre-pregnancy, LONG_EXP during pregnancy).
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【One case per day】Long-term complications after brain radiotherapy: SMART syndrome
Time of Update: 2022-11-04
MRI (1B) from a year ago showed no cortical signal abnormalities and swelling, with mild dural thickening.
MRI (1B) from a year ago showed no cortical signal abnormalities and swelling, with mild dural thickening.
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Autophagy Review—Li Xiaojiang's team reviews the differences and research progress of mitochondrial autophagy in vivo and in vitro models
Time of Update: 2022-11-04
V. Summary and prospectsIn this review, the authors focus on the main differences between PINK1-PRKN-mediated mitophagy in vitro and in vivo models, and discuss the reasons for these differences, with the aim of understanding how PINK1 performs its function in different environments, and thus for the study of PINK1 The important function of PRKN in the primate brain, exploring the mechanism of PD pathogenesis caused by two mutations and finding possible treatment strategies provide new research ideas.
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Step-by-hand reading 05: Acute disseminated encephalomyelitis
Time of Update: 2022-11-04
Produced by Medical FilmMedical Film has opened a new learning column [Teach you to read films by hand]. This column will select a number of typical and valuable imaging cases, not only with the most
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This cerebral infarction is characteristic: a case of acute symmetric cerebellar mid-foot infarction
Time of Update: 2022-11-04
On the 6th day of admission, the whole brain DSA showed complete occlusion of the right vertebral artery, diffuse severe stenosis from the V4 segment of the left vertebral artery to the proximal end of the basilar artery, good visualization of bilateral inferior anterior cerebellar artery, moderate stenosis at the beginning of the right inferior cerebellar artery, and no obvious abnormalities in the bilateral superior cerebellar artery and posterior cerebral artery (Fig. 1c).
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【Bilingual case】Acute embolism of the middle cerebral artery
Time of Update: 2022-11-04
Cranial CTA: filling defect is seen in the proximal segment of the M1 segment of the right middle cerebral artery, and its distal vascular branch shows poorly.
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Spatial multiomics analysis of tumor microenvironment in glioblastoma
Time of Update: 2022-11-04
Today I would like to share with you an article published in Cancer Cell (IF:38. 585):Spatial multiomics to resolve tumor-host interdependence in glioblastomaPART01 Research BackgroundSingle-cell RNA
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HBM-Shang Huifang's research group used functional imaging technology to reveal markers of motor progress in Parkinson's disease
Time of Update: 2022-11-04
Written by - responsible editor - Wang Sizhen, Fang Yiyi Editor—Summer LeafParkinson's disease (PD) is one of the most common neurodegenerative diseases [1]. Patients with PD develop a range of motor
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【Case Lecture Hall】ADEM in acute disseminated encephalomyelitis
Time of Update: 2022-11-04
【Differential diagnosis】This plot can be used to distinguish ADEM from MSADEM (A–C upper three figures), MS (D–F lower three figures) 【Medical history】10-year-old boy, sudden fatigue.
【Differential diagnosis】This plot can be used to distinguish ADEM from MSADEM (A–C upper three figures), MS (D–F lower three figures) 【Medical history】10-year-old boy, sudden fatigue.
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EClinicalMedicine: Don't be obsessed with blind boxes, and have a high risk of suicide
Time of Update: 2022-11-04
Suicide is an increasingly common public health problem and one of the leading causes of death among young people worldwide. The relationship between gambling and suicide has been highlighted by previ
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Neurology case: spontaneous jump-torsion nystagmus due to medial bulbar infarction
Time of Update: 2022-11-04
Examination reveals spontaneous torsional nystagmus (beating to the left at the upper pole of the eye [top pole]) with a slight up-jumping component (video), right-sided weakness, and loss of sensation in the right hemisphere.
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The real reason behind cervical pain?
Time of Update: 2022-11-04
PreambleLeukemia is a heterogeneous group of hematopoietic malignancies caused by differentiation block, apoptosis disorder, and malignant proliferation of hematopoietic stem/progenitor cells at diffe
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European Radiology: Clinical application of MRI quantitative atrophy evaluation in patients with suspected Alzheimer's disease
Time of Update: 2022-11-04
The measurements are displayed as residuals and adjusted for age and sexThe results of this study suggest that brain MRI scans from non-academic memory clinics have a high failure rate for quantification of GMV and HCV without protocol optimization.
