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Online parent training platform for complementary treatments for disruptive behavior disorders in ADHD: a randomized controlled trial protocol
Time of Update: 2022-11-04
Research Discussion:Research Discussion:This clinical trial aims to validate the effects of a new, online, evidence-based intervention model that will allow for wider use within Brazil.
This clinical trial aims to validate the effects of a new, online, evidence-based intervention model that will allow for wider use within Brazil.
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Stroke Tiantan Wang Yongjun team: Rosuvastatin can slow the progression of carotid intimal thickness
Time of Update: 2022-11-04
This randomized, double-blind, placebo-controlled, multicenter, parallel-group study evaluated the effect of rosuvastatin 20 mg/day compared with placebo on the progression of CIMT in the Chinese of subclinical arteriosclerosis over a 104-week period.
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Alzheimers Dement: Middle-aged people with good cardiovascular conditions have a lower risk of dementia
Time of Update: 2022-11-04
Through a series of examinations of two population-based cohorts from different time periods, the Community Atherosclerosis Risk (ARIC) Study and the Age, Gene/Environmental Sensitivity (AGES)-Reykjavik Study, which sought to assess higher levels in middle age Whether improvements in CVH and CVH in middle age were associated with a lower risk of dementia.
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Research progress of stem cell therapy in Alzheimer's disease
Time of Update: 2022-11-04
Summary and outlookStem cell therapy has been proven to play a role in many mechanisms in the preclinical model of Alzheimer's disease, but the effective data support of clinical research is still insufficient, and its clinical application is also limited by many factors.
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Adv. SCI: Cell type-specific single-neuron level whole-brain function projection mapping method
Time of Update: 2022-11-04
In response to this problem, the brain-spatial informatics research team of Huazhong University of Science and Technology used the sparse labeling of the genetic function probe GCaMP6 to combine two-photon calcium imaging in vivo and fMOST imaging in vitro.
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MRI of Leigh syndrome on MRI and differential diagnosis
Time of Update: 2022-11-04
Leigh syndrome should be suspected when lesions have a largely symmetrical distribution, involving the brainstem, basal ganglia, and parathalamus third ventricle, alone or simultaneously, especially when T2 FLAIR and DWI signals are uneven, and the lesions have both diffuse and unrestricted areas.
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CT sign of optic nerve (Optic track sign)
Time of Update: 2022-11-04
When injected with an enhancer, the optic nerve appears as an unenhanced, low-density (signal) line-like structure on CT or MR images, surrounded by surrounding reinforced meningioma.
When injected with an enhancer, the optic nerve appears as an unenhanced, low-density (signal) line-like structure on CT or MR images, surrounded by surrounding reinforced meningioma.
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Dev Cell Tian Ye's team at the Chinese Academy of Sciences found that two sensory neurons in Caenorhabditis elegans can coordinate the systemic mitochondrial stress response through GPCR signals
Time of Update: 2022-11-04
Original link: style="margin-right: auto;margin-left: auto;outline: 0px;width: 30px;display: inline-block;">—END—The content is 【iNature】iNatureMitochondrial perturbations within neurons transmit stress signals to peripheral tissues, coordinating mitochondrial homeostasis throughout the organism for optimal adaptation.
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Lancet subjournal: Long-distance ischemic adaptation of Ji Xunming's team of Capital Medical University has a significant protective effect on stroke
Time of Update: 2022-11-04
On October 27, 2022, led by the team of Professor Ji Xunming of Capital Medical University, 84 hospitals in China cooperated in Lancet Neurology ( IF=60) published online titled “Chronic remote ischaemic conditioning in patients with symptomatic intracranial atherosclerotic stenosis (the RICA trial): a multicentre, randomised, double-blind sham-controlled trial in China", which found that long-range ischemic adaptation reduced the recurrence rate of stroke by 24% and the incidence of cardiovascular and cerebrovascular diseases by 30%.
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Imaging analysis of "pig nose sign"
Time of Update: 2022-11-04
Figure 4 shows the T2WI imaging of the first week of illness in the above case, and the figure on the right is a schematic of the "pig nose sign"Of course, seeing this, some people will also think that the T2WI chart in the second week of illness is also similar to the pig's nose.
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Cell: The combination of endothelial and parietal cells promotes prenatal human cerebral angiogenesis
Time of Update: 2022-11-04
Prenatal parietal cell development of the human brainThe authors performed unbiased clustering of the scRNA-seq dataset to identify four subtypes of parietal cells, including smooth muscle cells, classical pericytes, fibroblasts, and mitotic parietal cells (Figures 4A, 4B).
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A case of reversible corpus callosum pressure lesion syndrome in children
Time of Update: 2022-11-04
In short, the causes of RESLES in children are mostly central nervous system viral infections, clinically manifested as symptoms of encephalitis, meningitis or encephalopathy, which may be accompanied by low blood sodium, and imaging features are reversible lesions in the pressure of the corpus callosum, and the prognosis is mostly good.
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Science: Breakthrough! Chinese scholars have discovered a new target drug for depression, which has a rapid effect in 2 hours and no side effects
Time of Update: 2022-11-04
Figure 1 Research results (Source: Science)The fast-acting antidepressant designed by the researchers works by disrupting the interaction between the serotonin transporter (SERT) and neuronal nitric oxide synthase (nNOS) in the dorsal raphe nucleus (DRN).
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Medical film boutique Imaging manifestations of acute headache
Time of Update: 2022-11-04
(I=down, S=top)Vertebral artery dissection (VAD), a 37-year-old woman presents to the emergency department with right-sided headache and neck pain, and initial non-contrast CT (not shown) is negative.
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Molecular Psychiatry: Blood marker for early detection and diagnosis of postpartum depression
Time of Update: 2022-11-04
Postpartum depression (PPD) is the most common complication after childbirth, and its serious consequences can affect both the mother and the child. Maternal suicide accounts for 20% of postpartum dea
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Nat Chem Biol: Is the itch unbearable? Chinese scientists have discovered a new way to cure the "itch"
Time of Update: 2022-11-04
Su Dongpo said: "It is easy to endure pain, but it is difficult to endure itching. " "Modern science has found that human perception of pain and itching is regulated by specific neural circuits, but m
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Stroke: Optimal cerebral perfusion pressure and oxygen content of brain tissue in aneurysmal subarachnoid hemorrhage
Time of Update: 2022-11-04
In summary, in patients with subarachnoid hemorrhage of aneurysm, there is a nonlinear relationship between PbtO2 and the deviation of CPP and CPPopt.
In summary, in patients with subarachnoid hemorrhage of aneurysm, there is a nonlinear relationship between PbtO2 and the deviation of CPP and CPPopt.
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Imaging findings of Sturge-Weber syndrome
Time of Update: 2022-11-04
Sturge-Weber syndrome (SWS), also known as craniofacial hemangioma, is a rare congenital neurocutaneous syndrome, first reported by Sturge in 1879, Weber described its typical intracranial calcificati
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Mol Cell: a novel mechanism of amyotrophic lateral sclerosis and frontotemporal dementia
Time of Update: 2022-11-04
(4) How does this interaction change as the mutant FUS matures?Studies have shown that glycine (G) mutations begin to lose association with WT FUS at the earliest stages of FUS-RNA nucleation and condensate formation.
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European Radiology: Applications of radiomics in identifying Parkinson's disease
Time of Update: 2022-11-04
(a) Comparison of PD and NC in the Huashan cohort, and (b) Comparison of PD and NC in the Wuxi cohortIn this study, a DLR method was developed to diagnose PD and PD subgroups, and the proposed model has significantly improved diagnostic performance compared with existing methods, providing a practical imaging method for computer-aided diagnosis of PD.
