-
Categories
-
Pharmaceutical Intermediates
-
Active Pharmaceutical Ingredients
-
Food Additives
- Industrial Coatings
- Agrochemicals
- Dyes and Pigments
- Surfactant
- Flavors and Fragrances
- Chemical Reagents
- Catalyst and Auxiliary
- Natural Products
- Inorganic Chemistry
-
Organic Chemistry
-
Biochemical Engineering
- Analytical Chemistry
-
Cosmetic Ingredient
- Water Treatment Chemical
-
Pharmaceutical Intermediates
Promotion
ECHEMI Mall
Wholesale
Weekly Price
Exhibition
News
-
Trade Service
On December 15, 2014, AJNR magazine published the following case report
.
Patient male, 55 years of age, progressive bi-leg weakness, gait abnormalities, ataxia.
The patient has megaloblastic anemia
.
Synoptic symmetry signal enhancement in the posterior cord cord (shown by arrow) in the sagittal position STIR (Figure 1) and horizontal T2WI (Figure 2).
Subacute combined degeneration
Subacute combined degeneration is an acquired myelopathy caused by vitamin B12 deficiency and a rare cause
of posterior cord demyelination.
Clinical manifestations:
May cause more neurological deficits, including progressive paresthesia, ascending paresthesia, paralysis, ataxia, sphincter disturbances, and gait abnormalities
.
Megaloblastic anemia can be seen early in most subacute combined degeneration and may suggest a diagnosis of subacute combined degeneration, but some patients do not have megaloblastic anaemia
.
Key points of diagnosis:
MRI STIR and T2WI images show enhanced symmetry of the posterior cord (relatively rare lateral cords), and the "inverted V" sign is visible in the horizontal plane;
There may be a mild mass effect and contrast signal enhancement
.
Differential diagnosis: posterior cord myelopathy; HIV myelopathy; Nitric oxide poisoning; Copper deficiency; Cyanide poisoning; Spinal cord infarction; myelination; Other causes
of transverse myelitis.
Treatment: Vitamin B12
supplementation.
