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Summaptan, Zolmitriptan... One article masters the treatment of "cluster headache"
Time of Update: 2023-01-06
*For medical professionals onlyThese 5 things to know!Cluster headache (CH) is often clinically manifested as severe pain in the orbital, supraorbital, and/or temporal region of the strict unilateral
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Neurology—Liyuan Han's team systematically assesses the disease burden of stroke among young adults globally, regionally and nationally
Time of Update: 2023-01-06
Article conclusion and discussion, inspiration and prospectsAlthough age-standardized morbidity, mortality, and DALY rates of ischaemic stroke in young adults declined globally between 1990 and 2019, in low- and middle- and low-SDI regions such as North Africa, the Middle East and Southeast Asia, The burden of ischaemic stroke is still increasing.
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The diagnosis and treatment of choreoa and tardive dyskinesia related to Huntington's disease in adults was explained at this summit forum
Time of Update: 2023-01-06
On October 29, 2022, the first Deuterium Tetrabenazine China-West International Summit Forum was successfully held in Chengdu, where many experts in neurology and psychiatry at home and abroad shared their experience in TD and HD treatment, opening up a smooth life path for more patients.
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For the diagnosis of migraine in pregnancy, the guidelines summarize these 4 points
Time of Update: 2023-01-06
Download the Decision Assistant App, the guide is free at any time ~▼▼▼Click to read the original article to download the AppWhat are the diagnostic criteria for major diseases?
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For the diagnosis of migraine in pregnancy, the guidelines summarize these 4 points
Time of Update: 2023-01-06
Download the Decision Assistant App, the guide is free at any time ~▼▼▼Click to read the original article to download the AppWhat are the diagnostic criteria for major diseases?
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Electric sparks in the brain: stories of ion channels and nerve cells
Time of Update: 2023-01-06
Electric sparks in the brain: stories of ion channels and nerve cellsauthorTranslated by Bert Sakmann (Professor at the Max Planck Institute for Neurobiology, winner of the 1991 Nobel Prize in Physiology and Medicine).
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2022 ESO Guidelines: "Screening for subclinical atrial fibrillation after unexplained ischemic stroke or transient ischemic attack" released
Time of Update: 2023-01-06
Question 3: For adult patients with unexplained ischaemic stroke or TIA, does an implantable monitoring device increase the detection rate of subclinical AF, improve anticoagulation rate, reduce recurrent stroke or systemic embolism, intracranial hemorrhage, any major bleeding, mortality compared with any non-implantable external monitoring device, And improved functional prognosis?
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2022 ESO Guidelines: "Screening for subclinical atrial fibrillation after unexplained ischemic stroke or transient ischemic attack" released
Time of Update: 2023-01-06
Question 3: For adult patients with unexplained ischaemic stroke or TIA, does an implantable monitoring device increase the detection rate of subclinical AF, improve anticoagulation rate, reduce recurrent stroke or systemic embolism, intracranial hemorrhage, any major bleeding, mortality compared with any non-implantable external monitoring device, And improved functional prognosis?
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"Cell" sub-journal: the first discovery of the neural circuit of sleep to consolidate social memory, the latest research results of the Chen Xiaowei/Qin Han team of the Army Medical University
Time of Update: 2023-01-06
Using techniques such as calcium flow in vivo imaging, optogenetics, and in vivo single-cell electrophysiology, they found that neurons projected by the hypothalamic supramammary nucleus (SuM) into the CA2 region of the hippocampus are highly activated during REM sleep, and that specific inhibition of this group of neurons during REM sleep impairs social memory.
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"Cell" sub-journal: the first discovery of the neural circuit of sleep to consolidate social memory, the latest research results of the Chen Xiaowei/Qin Han team of the Army Medical University
Time of Update: 2023-01-06
Using techniques such as calcium flow in vivo imaging, optogenetics, and in vivo single-cell electrophysiology, they found that neurons projected by the hypothalamic supramammary nucleus (SuM) into the CA2 region of the hippocampus are highly activated during REM sleep, and that specific inhibition of this group of neurons during REM sleep impairs social memory.
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Hu Gang's team revealed that microglia promote toxic astrocytes formation and induce depression-like behavior
Time of Update: 2023-01-06
1038/s41586-022-05328-2The images in the article are from referencesFigure 1: Increased activation of hippocampal neurotoxic astrocytes after stress2NLRP3 regulates the increase of astrocytes in the hippocampusGiven that NLRP3 regulates phenotypic transitions in A1 astrocytes and increases hippocampal NLRP3 levels after CMS, they constructed NLRP3 total knockout mice and found that knocking out NLRP3 was able to attenuate CMS-induced depression-like behavioral disorders, reduce the number of hippocampal A1 astrocytes, and attenuate synaptic protein loss.
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After publishing acupuncture research in Nature and revealing the existence of acupuncture points, Harvard full professor Ma Qiufu returned to China and joined Westlake University
Time of Update: 2023-01-06
In October 2021, Ma Qiufu's team and others published a paper in Nature to achieve a historic breakthrough in acupuncture research, which showed a class of PROKR2-Cre-labeled dorsal root ganglia (DRG) Sensory neurons are essential for low-intensity acupuncture stimulation to activate the vagus-adrenal anti-inflammatory pathway.
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The risk of stroke in young people has risen dramatically! JAMA is here to give you a wake-up call
Time of Update: 2023-01-06
conclusionUsing data from the Oxford Vascular Study, the researchers explored whether stroke rates changed between 2002 and older people in young and old people, which included 94,567 people registered at GP clinics in Oxfordshire.
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Microglia sense amyloid plaque hardness through Piezo1 to limit Alzheimer's disease progression Cell Press spoke to scientists
Time of Update: 2023-01-06
Life SciencesLife scienceRecently, Professor Mo Wei's team of Xiamen University published the research results entitled "Microglial Piezo1 senses Aβ fibrils stiffness to restrict Alzheimer's disease"
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Frontier Science: Seizure frequency reduced by 80%! Innovative gene therapies show amazing results
Time of Update: 2023-01-06
▲If you have any business needs, please press and hold to scan the QR code above, or▎WuXi AppTec content team editorScientists at University College London (UCL) have successfully developed a method that can reduce the excitability of overactive brain cells, which can effectively treat epilepsy - the seizures of the mice in the experiment fell by an average of 80%.
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Frontier Science: Seizure frequency reduced by 80%! Innovative gene therapies show amazing results
Time of Update: 2023-01-06
▲If you have any business needs, please press and hold to scan the QR code above, or▎WuXi AppTec content team editorScientists at University College London (UCL) have successfully developed a method that can reduce the excitability of overactive brain cells, which can effectively treat epilepsy - the seizures of the mice in the experiment fell by an average of 80%.
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NKGen advances NK cell therapy for Parkinson's, "tumor killer" can also treat neurodegenerative diseases?
Time of Update: 2023-01-06
The focus is on helping to accelerate NKGen's clinical program through its network of clinical partners and donors using its novel autologous NK cell therapy SNK01 for the treatment of advanced Parkinson's disease ( Parkinson’s disease,PD)。 Parkinson's disease is the second most common chronic, progressively developing central neurodegenerative disease after Alzheimer's disease, affecting nearly 10 million people worldwide.
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Dev Cell—Tian Ye's team found that the GPCR signaling pathway coordinates the body's mitochondrial stress response in a pair of sensory neurons
Time of Update: 2023-01-06
Written by Liu Yangli, edited by Zhou Jun -- Wang Sizhen, edited by Fang Yiyi -- Xia YeThe nervous system plays an important role in sensing and coordinating the body's stress response. When the mitoc
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New breakthrough in brain-computer interface: Zhang Fulun's team helps paralyzed aphasia "speak" by decoding brain activity
Time of Update: 2023-01-06
75em;"> style="margin-bottom: 0px;text-align: left;margin-left: 8px;margin-right: 8px;line-height: normal;">Open reprint, welcome to forward to Moments and WeChat groups EditorWang Duoyu TypesettingShui Chengwen Neuroprosthesis is a device that replaces missing nervous system function and is expected to restore the ability to communicate in patients who are unable to speak or type due to paralysis.
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Expert Review: Cell Xu Huaqiang/Xie Xin/Wang Mingwei/Zhuang Youwen collaborated to reveal the mechanism of action of the powerful analgesics fentanyl and morphine
Time of Update: 2023-01-06
On November 10, 2022, the team of Xu Huaqiang/Zhuang Youwen, Xie Xin's team and Wang Mingwei's team from the Shanghai Institute of Materia Medica, Chinese Academy of Sciences published a long article entitled Molecular recognition of morphine and fentanyl by the human μ-opioid online Research paper by Receptor.