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For medical professionals only
The Hamilton Anxiety Scale/Hamilton Depression Scale, and the Neuropsychiatric Questionnaire (NPI) can be used as reference assessment scales
.
What is the clinical diagnostic process for mild cognitive impairment? What are the medications for people with mild cognitive impairment of Alzheimer's disease?
Open the decision assistant App clinical guideline module to search for disease names and dialogue authoritative guidelines at home and abroad! 👇 Download the Decision Assistant App, the guide is free at any time ~
References: [1] Chinese expert consensus on the diagnosis and treatment of Alzheimer's pathogenic mild cognitive impairment 2021 ▼▼▼Click to read the original article to download the App
For more guidelines for the diagnosis and treatment of common neurological diseases, go to the "Clinical Decision Assistant App"!
Mild cognitive impairment (MCI) is an intermediate stage between cognitive normalization and Alzheimer's disease (AD) dementia, with a high probability
of outcome to AD dementia.
How to diagnose Alzheimer's pathogenic mild cognitive impairment, see the "Chinese Expert Consensus on the Diagnosis and Treatment of Alzheimer's Pathogenic Mild Cognitive Impairment (2021)" puts forward these three points!
1
Take a medical history and master these 6 points- Contents: onset time, form of onset, specific manifestations, progression mode, diagnosis and treatment process and prognosis
.
- Whether cognitive impairment has an impact on
daily abilities and social functioning.
- Whether there are non-cognitive neuropsychiatric symptoms (NPS), specific manifestations of NPS, and sequence of occurrence with cognitive impairment
.
- Possible triggers or events
for cognitive impairment.
- Concomitant signs and symptoms of limb dysfunction or other systemic disorders
.
- MCI due to neurodegenerative disease has an insidious onset, continues to progress, generally has no known disease causing cognitive impairment in the course of the disease, and often has no focal neurologic signs or selective involvement of a system
.
Detailed family history, history of neoplasms (to screen for paraneoplastic syndromes), history of blood transfusions and metallurgy (syphilis or HIV infection), past medical history, and particular attention to disorders or precipitating factors that cause cognitive impairment such as cerebrovascular disease, Parkinson's disease and Parkinson's superimposed syndrome, normal stress hydrocephalus, brain trauma, encephalitis, epilepsy, chronic diarrhea, or malnutrition (vitamin B1 or B12 and other deficiencies), thyroid dysfunction, liver and kidney insufficiency, alcoholism, carbon monoxide poisoning, drug abuse, vascular risk factors (such as hypertension and diabetes), depression, sleep breathing disorders, etc
.
2
Physical examination, including these 7 items★2.
1 General physical examination 2.
2 Neurological examination ★
: These include consciousness, advanced cortical function tests (comprehension, orientation, near and far memory, calculation, and judgment), cranial nerves, motor system (muscle volume, muscle tone, muscle strength, involuntary movement, ataxia, gait), sensory system (superficial sensation, deep sensation, compound sensation), reflexes (superficial reflex, deep reflex, pathological reflex), and meningeal irritation
.
3
Neuropsychological assessment, master these 3 tricks★3.
1 Assessment of cognitive function: 3.
1.
1 Overall cognitive function screening:
MoCA and/or modified ACE III are recommended as screening scales
.
3.
1.
2 Memory assessment:
- You can choose the California word learning test, the Chinese version of the Hopkins word learning test, and delayed free clue recall
.
- For the diagnosis of MCI in highly educated individuals, it is recommended that regular neuropsychological scale tests and longitudinal follow-up comparisons be used to detect cognitive decline and conversion to AD
.
3.
1.
3 Perform function evaluation: It is recommended to choose the connection test and the number sign conversion test
.
3.
1.
4 Language proficiency assessment: You can choose Boston naming test, semantic fluency test, Chinese aphasia set test
.
3.
1.
5 ReyOsterricth complex graphics test, drawing clock test, etc
.
★3.
2 Daily and social competency assessment:
- Includes assessment of basic daily living abilities and instrumental daily living skills
.
- Commonly used scales to evaluate the application of daily ability include the Alzheimer's Disease Collaborative Research Group MCI Daily Activity Scale (ADCSMCIADL), Lawton Instrumental Daily Activity Scale, and Social Functioning Questionnaire (FAQ).
★3.
3 NPS Assessment
- The most common symptoms are apathy, depression, anxiety, and abnormal
nighttime sleep behavior.
The Hamilton Anxiety Scale/Hamilton Depression Scale, and the Neuropsychiatric Questionnaire (NPI) can be used as reference assessment scales
.
What is the clinical diagnostic process for mild cognitive impairment? What are the medications for people with mild cognitive impairment of Alzheimer's disease?
Open the decision assistant App clinical guideline module to search for disease names and dialogue authoritative guidelines at home and abroad! 👇 Download the Decision Assistant App, the guide is free at any time ~
References: [1] Chinese expert consensus on the diagnosis and treatment of Alzheimer's pathogenic mild cognitive impairment 2021 ▼▼▼Click to read the original article to download the App