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Hunger state: the molecular mechanism of neuron and astrocyte "love and kill each other"
Time of Update: 2021-06-01
In order to further find the mechanism by which AgRP neurons regulate Ghrelin-induced depolarization of astrocytes in the ARC brain area, in vitro electrophysiological experiments have found that the incubation of AgRP and neuropeptide Y does not affect the hypothalamic astrocytes.
1172/JCI144239, the pictures in the text are all from the reference Baidu Netdisk Original download: https://pan.
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Stroke: Should patients with cerebral small vascular disease enhance blood pressure or standard blood pressure?
Time of Update: 2021-06-01
Intensive blood pressure reduction in patients with severe cerebral small vessel disease has nothing to do with the white matter damage detected by diffuse diffusion tensor imaging or magnetic resonance imaging.
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Anxiety associated with stroke-how far is it from us?
Time of Update: 2021-06-01
Post-stroke anxiety patients often have physical symptoms as their main manifestations.
Timely and effective management of anxiety symptoms can not only promote the recovery of patients, but also prevent the occurrence of post-stroke depression.
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15-year-old girl with acute cerebral infarction, intravenous thrombolysis has not improved!
Time of Update: 2021-06-01
According to the patient’s recent 2 months’ medical history, intraoperative findings and bedside cardiac color Doppler ultrasound results, atrial myxoma is likely to cause embolic cerebral infarction.
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Lancet Neuro: It's all strokes, why is he stupid and she is not?
Time of Update: 2021-06-01
Generally speaking, the location of the stroke infarct is a potential factor in determining PSCI, and about half of patients with post-stroke cognitive impairment (PSCI) occur in the first year after stroke.
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Remember the ice bucket challenge?
Time of Update: 2021-06-01
*Only for medical professional knowledge reading reference Although several years have passed since the ice bucket challenge, amyotrophic lateral sclerosis still deserves continuous attention. *This
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Neuropathol Appl Neurobiol: The p-Tau protein in the entorhinal cortex may be a key factor in women's susceptibility to Alzheimer's disease
Time of Update: 2021-06-01
Secondly, it quantitatively studied the gender differences of Aβ, Aβ42 and p-Tau protein in the entorhinal cortex of well-matched women (31) and men (21) with complete clinical cognition.
008, B) only exists in people over 80 years old ( 100 males, 253 females) and significant differences (Braak stage : p≤0.
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Stroke: Predictive performance of polygenic risk score for ischemic stroke in healthy elderly
Time of Update: 2021-06-01
do?w=%E5%BF%83%E8%A1%80%E7%AE%A1">heart blood vessels published a research article on the disease areas authoritative journal Stroke, researchers predict the risk of participating in ASPREE test 12,792 healthy elderly with IS events.
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6 cases give you a deep understanding of the imaging performance of DNET
Time of Update: 2021-06-01
Figure 4 In the temporal cortex, there are clearly defined wedge-shaped long T1 long T2 abnormal signals, no enhancement, and five basic medical history of cases with triangle sign: male, 12 years old, history of epilepsy.
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JNNP: Comparison of immune checkpoint inhibitor-related neuropathy in patients with neuroendocrine tumors and non-neuroendocrine tumors
Time of Update: 2021-06-01
Before the start of ICI, it is important to identify the clinical features of the pre-existing paraneoplastic neuropathy and the evaluation of tumor nerve autoantibodies to avoid the irreversible deterioration of the neurological function of these patients.
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The diagnosis process and ideas of dizziness are thoroughly explained!
Time of Update: 2021-06-01
Dizziness involves many disciplines such as otolaryngology, neurology, neurosurgery, orthopedics, ophthalmology, internal medicine, geriatrics, and psychiatry, because the specialization of various clinical disciplines may cause the disconnection of multidisciplinary connections, and the causes of dizziness are diverse and complex Therefore, when diagnosing dizziness, it is necessary to follow a complete and orderly process to avoid misdiagnosis and missed diagnosis.
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JAMA Neurol: NO2 in air pollution can increase the risk of Parkinson's disease
Time of Update: 2021-06-01
There is a significant statistical correlation between nitrogen dioxide exposure and Parkinson's disease risk, and this finding indicates the role of air pollutants in the pathological progression of PD.
There is a significant statistical correlation between exposure to nitrogen dioxide and the risk of Parkinson's disease.
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Stroke: The benefits and risks of dual and single antiplatelet therapy for the prevention of secondary stroke
Time of Update: 2021-06-01
It can be seen that DAPT is more effective than SAPT in preventing secondary ischemic stroke when anticoagulation therapy is started after a mild stroke/high-risk transient ischemic attack and the duration is less than 90 days .
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Neurology: The effect of neurofeedback promotion on gait and balance recovery after stroke
Time of Update: 2021-06-01
In summary, the use of fNIRS neurofeedback may enhance gait and balance recovery after stroke by adjusting SMA and its related networks.
In summary, the use of fNIRS neurofeedback may enhance gait and balance recovery after stroke by adjusting SMA and its related networks.
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Real-world study of Asian population: incidence of severe skin adverse reactions caused by anti-epileptic drugs
Time of Update: 2021-06-01
Research method This study collected 7 kinds of first prescriptions of carbamazepine, phenytoin, oxcarbazepine, lamotrigine, zonisamide, levetiracetam and topiramate in the Korean medical insurance database from January 2012 to December 2018 All patient data of antiepileptic drugs are used for correlation analysis of the incidence of serious skin adverse reactions.
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JNNP: Microstructural plasticity of nociceptive pathways after spinal cord injury
Time of Update: 2021-06-01
Based on recent studies showing that activity-dependent plasticity can be transformed into changes in myelin structure, this article hypothesizes that this pathophysiological process will be reflected in the microstructural changes in myelin and iron content along noxious pathways.
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Tsinghua University's Liu Qinghua team reveals the neural circuit mechanism of "creepy"
Time of Update: 2021-06-01
Through immunofluorescence experiments, wild-type mice were found to activate a large number of neurons in the posterior subthalamic nucleus (PSTh), lateral parabrachial subnucleus (PBel) and nucleus tractus solitarius (NTS) after smelling 2MT, while Trpa1 was knocked out Neuronal activation in these brain regions is reduced in mice.
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Neurol Neuroimmunol Neuroinflamm: OCT to check the thickness of the retinal layer helps early recognition of the risk of cognitive impairment in patients with multiple sclerosis
Time of Update: 2021-06-01
studied the relationship between RLT in patients with multiple sclerosis and the cognitive ability in the International MS Medical Cognitive Assessment (BICAMS), as well as the attention and executive function tests of outpatients with mild to moderate clinical deficits to explore the orientation of OCT The potential of CI.
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Middle-aged women who have no obvious cause are slow to respond and confused in speech. What are the reasons?
Time of Update: 2021-06-01
Click to enter the mini program, check the answer, and enter the mini program below [Yimaitong case exchange] to learn and discuss with your comrades!
☟☟☟↓↓↓ Click to read the original text, view the answer and more videos and discussions~
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Reverse the "shutdown" of immune cells and protect the aging brain
Time of Update: 2021-06-01
They found that no matter which method is used, inhibition of EP2 receptor function can restore macrophage metabolism to a young level, reduce peripheral and central inflammation, and thereby alleviate cognitive decline (Figure 1).
