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For medical professionals to read only for reference.
What is DNET? Dysembryoplastic Neuroepithelial tumor (DNET) is an uncommon benign intracortical lesion.
The WHO classifies it as a "neuronal and mixed glial tumor", which is often accompanied by cortical dysplasia .
It is common in young patients (less than 20 years old) and is more common in men.
The most common location is the temporal lobe (62%), followed by the frontal lobe.
Imaging manifestations of DNET are mostly clear-bounded, wedge-shaped vesicular intracortical masses.
On CT, they are mostly low-density and wedge-shaped changes, showing cortical or subcortical wedge-shaped lesions, with the tip pointing to the ventricle, which can be seen in 25% of cases Calcification is formed.
On MR, it shows long T1 and long T2 signals with clear borders.
Most of them are triangles with the surface of the brain as the base, and the tip points to the deep part of the brain, which is called the triangle sign.
The inside of the tumor is pseudocystic, multi-nodular vesicles, and sometimes it can also be expressed as soap bubble-like giant gyrus.
There are cord-like iso-signal separations extending from the edge to the center in the tumor.
There is generally no edema around the tumor and no mass effect.
Usually manifested as no enhancement, a few can also be local enhancement or nodular enhancement.
The following are related literature reports and clinical cases encountered, which can provide a deeper understanding of the imaging performance of DNET.
Case 1 Basic medical history: A 17-year-old man developed intractable epilepsy.
Figure 1 Abnormal signal of T1 and T2 is seen in the right temporal cortex, the border is clear, the coronal position shows a triangle sign, the tip points to the ventricle, and there is no enhancement.
Case 2: Female, 14 years old, with occasional epilepsy.
Figure 2 The left frontal lobe has a patchy long T1 long T2 abnormal signal, which is distributed like a gyrus.
Three cases with triangular sign can be seen in the sagittal view.
Three medical histories: female, 33 years old, with sudden convulsions for 2 days.He has a history of "epilepsy" for more than 10 years and has not taken regular medication.
Fig.
3 Abnormal signal of vesicle-like long T1 and long T2 is seen in the left frontal-parietal junction area, FLAIR is a mixed signal of high and low, and slight enhancement in the form of cords can be seen after the injection of contrast agent.
Part of the lesions can be seen with iron-containing blood yellow deposits.
Case 4 There was a report of the disease in a typical lesion picture analysis of AJNR on February 28, 2014.
The basic medical history is unknown.
Figure 4 In the temporal cortex, there are clearly defined wedge-shaped long T1 long T2 abnormal signals, no enhancement, and five basic medical history of cases with triangle sign: male, 12 years old, history of epilepsy.
Figure 5 The left posterior cingulate cortex shows abnormal T1 signals such as T2, FLAIR is high signal, and the lesion has no mass effect.
Six basic medical history: female, 45 years old, with tonic-clonic seizures.
Fig.
6 Abnormal signals of T1 and T2 are seen in the medial cortex of the right temporal lobe.
The boundary is requested.
There is no space-occupying effect.
The enhancement shows that the pathological changes of punctate enhancement are mainly composed of oligodendrocytes, astrocytes and neurons.
The ingredients are mixed, and the proportion, cell distribution and arrangement of various cells vary greatly.
Specific glioneuronal element (SGNE): for its characteristic pathological changes, it is composed of axons arranged in bundles, often distributed perpendicular to the surface of the cortex.
The differential diagnosis mainly needs to be differentiated from other neuroepithelial tumors that are more likely to occur in the cortex, such as: ganglion cell glioma, gangliocytoma, oligodendrocyte and mixed oligodendrocyte-astrocytoma, pleomorphic yellow astrocytoma Cell tumor and protoplasmic astrocytoma, etc.
Main imaging signs: 1.
Triangle sign: related to the radial distribution of glial fiber pathways; 2.
Intratumoral separation: related to the lobular appearance of the tumor.
What is DNET? Dysembryoplastic Neuroepithelial tumor (DNET) is an uncommon benign intracortical lesion.
The WHO classifies it as a "neuronal and mixed glial tumor", which is often accompanied by cortical dysplasia .
It is common in young patients (less than 20 years old) and is more common in men.
The most common location is the temporal lobe (62%), followed by the frontal lobe.
Imaging manifestations of DNET are mostly clear-bounded, wedge-shaped vesicular intracortical masses.
On CT, they are mostly low-density and wedge-shaped changes, showing cortical or subcortical wedge-shaped lesions, with the tip pointing to the ventricle, which can be seen in 25% of cases Calcification is formed.
On MR, it shows long T1 and long T2 signals with clear borders.
Most of them are triangles with the surface of the brain as the base, and the tip points to the deep part of the brain, which is called the triangle sign.
The inside of the tumor is pseudocystic, multi-nodular vesicles, and sometimes it can also be expressed as soap bubble-like giant gyrus.
There are cord-like iso-signal separations extending from the edge to the center in the tumor.
There is generally no edema around the tumor and no mass effect.
Usually manifested as no enhancement, a few can also be local enhancement or nodular enhancement.
The following are related literature reports and clinical cases encountered, which can provide a deeper understanding of the imaging performance of DNET.
Case 1 Basic medical history: A 17-year-old man developed intractable epilepsy.
Figure 1 Abnormal signal of T1 and T2 is seen in the right temporal cortex, the border is clear, the coronal position shows a triangle sign, the tip points to the ventricle, and there is no enhancement.
Case 2: Female, 14 years old, with occasional epilepsy.
Figure 2 The left frontal lobe has a patchy long T1 long T2 abnormal signal, which is distributed like a gyrus.
Three cases with triangular sign can be seen in the sagittal view.
Three medical histories: female, 33 years old, with sudden convulsions for 2 days.He has a history of "epilepsy" for more than 10 years and has not taken regular medication.
Fig.
3 Abnormal signal of vesicle-like long T1 and long T2 is seen in the left frontal-parietal junction area, FLAIR is a mixed signal of high and low, and slight enhancement in the form of cords can be seen after the injection of contrast agent.
Part of the lesions can be seen with iron-containing blood yellow deposits.
Case 4 There was a report of the disease in a typical lesion picture analysis of AJNR on February 28, 2014.
The basic medical history is unknown.
Figure 4 In the temporal cortex, there are clearly defined wedge-shaped long T1 long T2 abnormal signals, no enhancement, and five basic medical history of cases with triangle sign: male, 12 years old, history of epilepsy.
Figure 5 The left posterior cingulate cortex shows abnormal T1 signals such as T2, FLAIR is high signal, and the lesion has no mass effect.
Six basic medical history: female, 45 years old, with tonic-clonic seizures.
Fig.
6 Abnormal signals of T1 and T2 are seen in the medial cortex of the right temporal lobe.
The boundary is requested.
There is no space-occupying effect.
The enhancement shows that the pathological changes of punctate enhancement are mainly composed of oligodendrocytes, astrocytes and neurons.
The ingredients are mixed, and the proportion, cell distribution and arrangement of various cells vary greatly.
Specific glioneuronal element (SGNE): for its characteristic pathological changes, it is composed of axons arranged in bundles, often distributed perpendicular to the surface of the cortex.
The differential diagnosis mainly needs to be differentiated from other neuroepithelial tumors that are more likely to occur in the cortex, such as: ganglion cell glioma, gangliocytoma, oligodendrocyte and mixed oligodendrocyte-astrocytoma, pleomorphic yellow astrocytoma Cell tumor and protoplasmic astrocytoma, etc.
Main imaging signs: 1.
Triangle sign: related to the radial distribution of glial fiber pathways; 2.
Intratumoral separation: related to the lobular appearance of the tumor.
