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Diagnostic points for olive pontine cerebellar atrophy (crucifixion)
Time of Update: 2022-09-30
The appearance of "cross signs" from the image alone can only be considered MSA, but the case for OPCA, SND, or Shy-Drager syndrome needs to be closely combined with the clinic.
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Movement disorders: Digitized gait biomarkers can capture longitudinal changes in type 3 cerebellar ataxia over a 1-year period
Time of Update: 2022-09-30
However, to be an effective progression biomarker, these gait measurements must demonstrate their sensitivity to strongly capture longitudinal changes, preferably in a short period of time (e.
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Brain: A novel mechanism for the mislocalization of RNA-binding proteins in amyotrophic lateral sclerosis
Time of Update: 2022-09-30
The study used time-resolved hiPSCs for deep sequencing of the nuclear and cytoplasmic parts of motor neurogenesis, revealing that mutations in the VCP gene causing ALS lead to the accumulation of compartmental-specific abnormalities in IRT.
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A new method of non-invasive testing! Parkinson's disease and multisystem atrophy can be diagnosed in this way
Time of Update: 2022-09-30
Saliva RT-QuIC method to detect the inoculation activity of α-synuclein The symptoms of Parkinson's disease (PD) and multiple system atrophy (MSA) are more similar and difficult to diagnose and distinguish between clinical symptoms early.
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The study revealed brain molecular changes associated with APOE4, the main susceptibility gene for Alzheimer's disease
Time of Update: 2022-09-30
： ， 。 Video Mini Program like, tap twice to cancel like in viewing, tap twice to cancel in viewing Recent breakthroughs have revealed a lot of information about Alzheimer's disease, but researchers have yet to paint a complete picture of how the genetic risk of the disease leads to brain damage, ultimately leading to memory loss and cognitive decline.
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Rehabilitation of stroke aphasia
Time of Update: 2022-09-30
4 Aphasia assessmentThe examination and evaluation of aphasia is to understand the specific level of listening, speaking, reading and writing of patients, and is the process of initially mastering the language function, and the results can be used as the basis for comparing the effects before and after training.
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Neurology: Ubrogepant in the treatment of mild pain in the acute phase of migraine versus moderate pain in severe pain
Time of Update: 2022-09-30
gov for NCT02873221)This study provides class III evidence that ubroepant, 50 mg or 100 mg used by adults with mild migraine, increases the likelihood of being free from migraine headache pain, migraine-related symptoms, and disability after 2 hours compared with moderate to severe migraine.
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Neuron: Youming Lu/Lingqiang Zhu's team at Huazhong University of Science and Technology reveals two types of cholinergic neurons that regulate anxiety and spatial memory
Time of Update: 2022-09-30
On September 20, 2022, the research team of Lu Youming/Zhu Lingqiang of Tongji Medical College of Huazhong University of Science and Technology published an article in the journal Neuron that revealed that there are two types of cholinergic neurons with different structures (projected to different hippocampal regions) and different functions (anxiety behavior and spatial memory) in the medial septal nucleus.
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MRI diagnosis of posterior cruciate ligament (PCL) injury
Time of Update: 2022-09-30
MRI grading of posterior cruciate ligament injuryIndirect manifestation of posterior cruciate ligament tearing1.
MRI grading of posterior cruciate ligament injuryIndirect manifestation of posterior cruciate ligament tearing1.
MRI grading of posterior cruciate ligament injuryIndirect manifestation of posterior cruciate ligament tearing1.
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Intravenous thrombolytic therapy – acute ischemic stroke**: rtPA intravenous thrombolysis, how to use rtPA?
Time of Update: 2022-09-30
Randomized controlled trials have shown that intravenous rt-PA thrombolysis within 3 hours of the onset of neurologic symptoms in screened patients with acute ischemic stroke is a very effective treatment (class A evidence) at a recommended dose of 0.
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Brain: Neuroimaging features of brain injury in Wilson's disease—a multimodal whole-brain MRI study
Time of Update: 2022-09-30
In chronically treated and stable patients, the severity of neurological deficits is associated with gray matter volume and is concentrated in the subcortical brain region (Figure 1).
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AD: Features and significance of neurologic examination results in autosomal dominant Alzheimer's patients
Time of Update: 2022-09-30
： ， 。 Video Mini Program like, tap twice to cancel like in viewing, tap twice to cancel in viewing ADAD autosomal dominant Alzheimer's disease (ADAD) is a rare single-genotype of Alzheimer's disease.
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BMJ subjournal: Incidence of gastroesophageal reflux disease in children with nerve impairment
Time of Update: 2022-09-30
Gastroesophageal reflux disease (GERD) is often accompanied by painful symptoms and serious complications, and in recent years, the diagnosis of GERD has become increasingly common in children, and acid-suppressing drugs (ASMs) have been prescribed, including proton pump inhibitors (PPIs) and histamine-2 receptor antagonists (H2RA).
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Clinical manifestations of psychogenic non-epileptic seizures in children: experience from a single center
Time of Update: 2022-09-30
An accurate and timely diagnosis of psychotic non-seizures (PNES), a type of transgenic disease, is challenging because its clinical manifestations are manifestations of epilepsy and related medical and psychiatric comorbidities.
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Management of acute ischemic stroke during anticoagulation of atrial fibrillation
Time of Update: 2022-09-30
It's so divineFAST breaks the "taboo", and the 95-year-old man escapes from deathExamination items and timing of 10 complications of diabetes Acute ischemic stroke (CIS) has surpassed cardiovascular disease and malignant tumors in China and become the first cause of death.
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Heat really kills people – "hot out" tests report critical values
Time of Update: 2022-09-30
prefaceEntering the summer, many places in the country open the "steaming" mode, there have been reports of deaths due to heat stroke, heat stroke is the most serious condition of heat-related emergen
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Neuroreview Research advances in venous thrombolysis in acute ischemic stroke with atrial fibrillation
Time of Update: 2022-09-30
Atrial fibrillation is an independent risk factor for ischemic stroke, and studies have shown that atrial fibrillation increases the risk of ischemic stroke by a factor of 4 to 5 when other vascular r
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Differentiation of cerebral atrophy and hydrocephalus
Time of Update: 2022-09-30
The first trickFrontal angleBrain atrophy - blunt angleBrain atrophy - blunt angleHydrocephalus - acute angleHydrocephalus - acute angleThe second trickFrontal Angle Ratio - The widest part of the fro
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JNNP: Using an intermediate ATXN2-polyQ repeat, to explore phenotyping in patients with Italian ALS
Time of Update: 2022-09-30
A large population-based cohort of Italian ALS patients without C9orf72, SOD1, TARDBP and FUS gene mutations was evaluated to determine the clinical features of ATXN2 polyQ intermediate repeat numbers.
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Nat Neurosci: Science has found that electrical stimulation through the scalp can improve a person's memory
Time of Update: 2022-09-30
Based on the study, the team showed that stimulating the dorsolateral prefrontal cortex (a region near the front of the brain) with high-frequency currents improves long-term memory, while stimulating the sub-parietal lobe located deeper in the brain, enhancing working memory with low-frequency currents.
