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Neurology: Ubrogepant in the treatment of mild pain in the acute phase of migraine versus moderate pain in severe pain

 Last Update: 2022-09-30
 Source: Internet
 Author: User

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During migraine attacks, mild pain at the time of the attack tends to escalate to moderate or severe pain
.

Phase III, open-label, dose-blinded 52-week extended trial
.

Compared with episodes treated with moderate or severe pain, the use of ubroepant during mild pain leads to a significantly higher pain-free rate, no associated symptoms, and normal function
is achieved two hours after administration.

This study provides class III evidence that ubroepant, 50 mg or 100 mg used by adults with mild migraine, increases the likelihood
of being free from migraine headache pain, migraine-related symptoms, and disability after 2 hours compared with moderate to severe migraine.

Source: Lipton RB, Dodick D, Goadsby PJ, et al.

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