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Women and men should take different antihypertensive drugs
Time of Update: 2021-11-04
Mykola MamenkoPhoto Credit: Michael Holahan, Augusta UniversityScientists say that another difference between women and men seems to be the key mechanism of how they develop high blood pressure, which determines which antihypertensive drugs are most effective for them .
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How many rings does the human nuclear pore complex in "Nature" have?
Time of Update: 2021-11-04
The researchers devised a method to study a huge doughnut-shaped structure called the nuclear pore complex (NPC) inside the cell .
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"China Model" solves the difficult problem of rare disease prevention and control
Time of Update: 2021-11-04
Let rare diseases be "seen"Not long ago, the Chief Physician Wan Xiaoqun of the Department of Cardiovascular Medicine of the First Affiliated Hospital of Xiamen University worked with multidisciplinary experts, and finally diagnosed a patient with amyloid cardiomyopathy that had been suffering for many years .
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Scientists have developed new sensors to capture calcium activity in cells
Time of Update: 2021-11-04
The research published in the journal Angewandte Chemie shows that the red calcium sensor called R-CatchER is very sensitive in detecting calcium signals in a variety of cells .
"We can monitor calcium events in healthy cells to see how they change in disease states .
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Spectroradiometer "ray gun" allows scientists to use light instead of DNA to distinguish plants
Time of Update: 2021-11-04
The researchers used a handheld device that looked a bit like a ray gun to record how the leaves of plants in different mountains in Alaska reflected light .
But this new study shows that the light reflected by leaves is different between different plant populations .
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The Zhejiang University team has developed a new polymer micelle, which is expected to treat intervertebral disc degeneration
Time of Update: 2021-11-04
These two molecules can protect human ADSCs from oxidative stress and promote cell differentiation into a nucleus pulposus-like phenotype, thereby treating intervertebral discs.
X-ray analysis to assess the height of the intervertebral discConcluding remarksIn summary, researchers have developed an injectable esterase-responsive micelle PAKM that delivers APO and KGN to the intervertebral disc .
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Wang Yingchun's research group systematically reveals that cyanobacteria are regulated by light/darkness in protein degradation
Time of Update: 2021-11-04
Light-regulated protein degradation is an important mechanism for protein quality control in photosynthetic organisms.
Figure: Proteomics technology identifies light and dark-regulated protein degradation in cyanobacteria
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The latest study by Chinese scholars found that intermittent dieting can improve fatty liver
Time of Update: 2021-11-04
A doctoral student in Chen Yan's research group, Zhao Jingyu, and others used a high-fat and high-sucrose diet to establish a fatty liver model in mice, and analyzed the effect of intermittent dieting as a dietary intervention strategy on fatty liver .
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New methods for glaucoma treatment
Time of Update: 2021-11-04
It affects 60 million people worldwideAt present, the only way to treat primary congenital glaucoma is surgeryNew treatments are urgently needed to slow down the vision loss of both types of glaucomaChicago News, a study conducted by Northwestern Medicine in mice has identified new treatment targets for glaucoma, including the prevention of a severe form of glaucoma in children, and the discovery of a possible treatment for the most common glaucoma in adults New type .
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"PNAS" cover The future of China's solar energy: meeting 43.2% of domestic electricity demand by 2060
Time of Update: 2021-11-04
"Our research results show that the economic competitiveness of solar energy combined with investment in storage systems can provide additional benefits for grid dispatch, which is particularly important for the operation of China's future power system .
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Sunscreens containing zinc oxide lose their effectiveness after 2 hours and are toxic
Time of Update: 2021-11-04
The research team from the University of Oregon and the University of Leeds found that in sunscreens containing zinc oxide particles, the UVA protection factor was reduced by 84.
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Legend Bio announces the latest progress in solid tumors and allogeneic CAR-T therapy
Time of Update: 2021-11-04
The CAR-T therapy cilta-cel, which targets B cell maturation antigen (BCMA), developed by Legend Bio and Janssen, has shown certain anti-cancer activity in clinical trials for the treatment of multiple myeloma .
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Li Zijian and others published a paper proposing a new fate of membrane receptor endocytosis-endocytosis activation
Time of Update: 2021-11-04
This article follows Li Zijian’s group’s invitation to propose the concept of receptor "endocytosis activation" in the Cell sub-Journal Trends in Cell Biology in April 2021 (Wenjing Wang, Jingwei Bian, Zijian Li, Internalized Activation of Membrane Receptors: From Phenomenon to Theory .
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Nature: DNA tangles can help predict the evolution of mutations
Time of Update: 2021-11-04
The authors of the study said that these findings will help us predict the evolution of bacteria and viruses over time in the future, which may help vaccine design and a better understanding of antibiotic resistance .
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Is fresh breast milk better for premature babies than pumped and stored breast milk?
Time of Update: 2021-11-04
Carrie-Ellen Briere, assistant professor of nursing at the University of Massachusetts Amherst, a former clinical nurse in the neonatal intensive care unit, is now engaged in breast milk research .
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The first time-space map of metabolites in the aging process of the mouse brain was established and opened
Time of Update: 2021-11-04
The data set includes 1,547 different molecules in 10 brain regions of male and female mice in the laboratory, changing from adolescence to adulthood to old age .
The research results were published in the journal Nature Communications under the title "a metabolome atlas of the aging mouse brain" .
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The chemical switch of genes may help explain why large mammals live longer
Time of Update: 2021-11-04
Horvath is known for showing that the patterns of these methyl groups change with ageCreate an "epigenetic clock"Use DNA samples to estimate a person’s age within 3.
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Nature: Humans did not cause the extinction of woolly mammoths
Time of Update: 2021-11-04
Humans have been accused because animals have not been extinct due to climate change in the previous millions of years, but when they live with humans When we were together, they did not last long, and we were accused of hunting them to death .
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JAMA: Changes in blood biomarkers for long-term space flight
Time of Update: 2021-11-04
Recently, researchers from the University of Munich in Germany, the University of Gothenburg in Sweden, and the Russian Academy of Sciences published in a sub-issue of the JAMA Neurology journal entitled "Blood biomarkers for brain damage and degeneration from long-term space flight" "Changes" research paper .
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Cell releases a technological leap: enabling scientists to study how proteins in cells change shape
Time of Update: 2021-11-04
Image source: Hahn/Elston, UNC School of MedicineUnderstanding how proteins bend, twist, and deform in cells is very important for understanding normal biology and disease .
Scientists envision that Binder-tag will eventually become a basic technology for studying normal proteins, larger multi-molecular structures in cells, and even dysfunctional proteins related to Alzheimer's disease .
