echemi logo
Product
  • Product
  • Supplier
  • Inquiry
    Home > Biochemistry News > Biotechnology News > JAMA: Changes in blood biomarkers for long-term space flight

    JAMA: Changes in blood biomarkers for long-term space flight

    • Last Update: 2021-11-04
    • Source: Internet
    • Author: User
    Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com

    As we all know, staying in space for a long time will have adverse effects on the astronaut's body, including muscle atrophy, osteoporosis, decreased vision and changes in the intestinal flora
    .

    Recently, researchers from the University of Munich in Germany, the University of Gothenburg in Sweden, and the Russian Academy of Sciences published in a sub-issue of the JAMA Neurology journal entitled "Blood biomarkers for brain damage and degeneration from long-term space flight" "Changes" research paper
    .

     

    The research team tracked five Russian male astronauts working on the International Space Station 400 kilometers from the Earth's surface
    .


    Through blood tests, they found their nerve filaments (NfL), glial fibrillary acidic protein (GFAP) and amyloid


     

     

    The research team collected blood samples 20 days before the five astronauts went to the International Space Station
    .


    The average time of the five astronauts on the space station is 169 days (about 5 and a half months), and the average age is 49 years old


     

    After they returned to Earth, follow-up blood samples were collected one day, one week, and approximately three weeks after landing
    .


    5 biomarkers for analysis of brain injury


     

    For the three brain injury biomarkers-NfL, GFAP and Aβ40, their concentrations increased significantly during their stay on the space station
    .

    After the astronauts returned to Earth, these brain damage markers did not change simultaneously, but the overall trend was consistent over time
    .


    It is understood that this is the first time that specific evidence of brain cell damage has been recorded in a blood test after a space flight


     

     

    Why does staying in space cause weightlessness-related brain damage, brain fluid changes, and overweight stress related to launch and landing? Or other unknown reasons? There is no clear answer yet
    .

     

    These changes may be related to brain function, as evidenced by changes in brain magnetic resonance imaging (MRI) of these astronauts after returning to Earth
    .


    However, due to the small scale of the study, with only 5 astronauts, it is impossible to further explore the specific relationship between this change and brain function


     

    In recent decades, the ability of mankind to explore space has advanced by leaps and bounds, and civil airlines such as Space X and Blue Origin have also begun to send mankind into space
    .


    Perhaps in the near future, space travel will become more common, which requires us to further explore the reasons for the signs of brain damage in space to further prevent this from happening


     Related paper links: https://jamanetwork.


    com/journals/jamaneurology/article-abstract/2784623

     (Source: Internet, reference only)


    This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

    Contact Us

    The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

    Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.