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Hepatocyte mutations associated with liver disease and fat metabolism
Time of Update: 2021-11-04
In addition, although more research is needed, this research may lead to a potential new model to understand how mutations in specific cell types can lead to systemic metabolic diseases, such as diabetes .
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Powell, a patient with multiple myeloma, died of COVID-19
Time of Update: 2021-11-04
But for patients with multiple myeloma, cancerous plasma cells will appear in the body, and these cancer cells will produce a large number of useless antibodies-these antibodies are not produced against a specific pathogen and have no protective effect .
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Emotional memories can be changed or forgotten!
Time of Update: 2021-11-04
Now, scientists at the University of Cambridge have proved the existence of a special protein, shank protein, which acts as a scaffold for the receptor and determines whether memory can be modified in animals treated with propranolol .
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Another set of immune systems for bacteria to defend against bacteriophages (BrxU)
Time of Update: 2021-11-04
The researchers demonstrated that the two defense systems work in complementary ways to protect bacteria from bacteriophages .
Therefore, a system called BrxU can protect bacteria from bacteriophages through modified DNA, thereby providing a second layer of defense .
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New methods for glaucoma treatment
Time of Update: 2021-11-04
It affects 60 million people worldwideAt present, the only way to treat primary congenital glaucoma is surgeryNew treatments are urgently needed to slow down the vision loss of both types of glaucomaChicago News, a study conducted by Northwestern Medicine in mice has identified new treatment targets for glaucoma, including the prevention of a severe form of glaucoma in children, and the discovery of a possible treatment for the most common glaucoma in adults New type .
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JAMA: Changes in blood biomarkers for long-term space flight
Time of Update: 2021-11-04
Recently, researchers from the University of Munich in Germany, the University of Gothenburg in Sweden, and the Russian Academy of Sciences published in a sub-issue of the JAMA Neurology journal entitled "Blood biomarkers for brain damage and degeneration from long-term space flight" "Changes" research paper .
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The chemical switch of genes may help explain why large mammals live longer
Time of Update: 2021-11-04
Horvath is known for showing that the patterns of these methyl groups change with ageCreate an "epigenetic clock"Use DNA samples to estimate a person’s age within 3.
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Nature: DNA tangles can help predict the evolution of mutations
Time of Update: 2021-11-04
The authors of the study said that these findings will help us predict the evolution of bacteria and viruses over time in the future, which may help vaccine design and a better understanding of antibiotic resistance .
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The Huang Tiejun research group of the School of Information publishes an article in the Cell sub-publishing to reveal the mechanism of biological retina encoding dynamic natural scenes
Time of Update: 2021-11-04
In order to break through the above-mentioned bottleneck, the research group of Professor Huang Tiejun from the Department of Computer Science and Technology of Peking University and the National Engineering Laboratory of Digital Video Coding and Decoding Technology proposed and implemented a retinal coding model based on convolutional recurrent neural network, which can predict with high precision.
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Nature: Genome analysis reveals Alpha and Delta variants swept England
Time of Update: 2021-11-04
Researchers in the United Kingdom recently conducted genome analysis of multiple isolates and found that COVID-19 in the United Kingdom is characterized by different SARS-CoV-2 virus strains that produce a variety of epidemics and sub-epidemics .
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Outdoor high temperature and low temperature are harmful to fetal growth during pregnancy
Time of Update: 2021-11-04
The study, published in the journal Environmental Health Perspectives, assessed the critical window period during which 624,940 single-born babies nationwide in Israel are susceptible to extreme low temperatures and high temperatures during pregnancy and fetal growth during 2010-2014 .
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Nature: Why the incidence of cancer is relatively low, but the number of mutant cells is very large
Time of Update: 2021-11-04
This paper published today (October 13, 2021) in the journal Nature shows that these high mutational cloning burdens create a highly competitive environment in which early tumors under the microscope are The mutant cells are difficult to grow until they are cleared of the tissue .
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Aging breast tissue may create conditions for invasive breast cancer
Time of Update: 2021-11-04
Women’s risk of being diagnosed with breast cancer increases with age, but when scientists have long studied the cellular changes that occur in the human body over time, a new study led by researchers at the University of Notre Dame examines the extracellular How the matrix (ECM) is-the underlying network of molecules and proteins that provide structure for tissue growth, which can trigger aggressive cancer-related genes .
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Science Advances: Can cancer cells mobilize the nervous system?
Time of Update: 2021-11-04
Researchers at the Technion-Israel Institute of Technology have developed an innovative breast cancer treatment based on analgesic nanoparticles targeting the nervous system .
Based on these findings, researchers have developed a treatment method that uses nerve cells to target tumors .
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Demonstrated for the first time the absolute efficacy of cell-based influenza vaccine for two-year-old children
Time of Update: 2021-11-04
According to a new study, a cell-based influenza vaccine has effectively provided protection against influenza for children and adolescents .
The study, published in The New England Journal of Medicine, demonstrated for the first time the absolute efficacy of cell-based influenza vaccines for two-year-old children .
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"ELife" Unexpected Benefit of Laughing Cats: Bacteria on Cats Can Treat Intractable Skin Infections
Time of Update: 2021-11-04
In order to identify a new bacterial therapy against skin infections, the researchers first screened various bacteria from dogs and cats and co-cultured them with S.
To solve this problem, the researchers first screened a pool of bacteria that usually live in dogs and cats, and cultivated them in the presence of MRSP .
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Science: The New Delhi epidemic highlights the serious challenge of achieving herd immunity in the face of Delta variants
Time of Update: 2021-11-04
An international team of scientists wrote in the journal Science that the severe COVID-19 outbreak in Delhi, India in 2021 showed that the Delta variant of SARS-CoV2 is not only extremely contagious, but it can also infect other people who have been infected before.
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Bojian Antisense Oligonucleotide Tofersen Treatment of ALS Phase 3 Clinical Failure
Time of Update: 2021-11-04
In addition, a pre-specified integration of data from the VALOR study and its ongoing open label extension study (OLE) reinforces these findings and shows that early initiation of tofersen therapy can lead to motor function and respiratory function in SOD1-ALS patients , Muscle strength and quality of life indicators decreased less .
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Research shows that an infrared light therapy may be helpful for people with dementia
Time of Update: 2021-11-04
Paul Chazot from the Department of Biological Sciences of Durham University, who is the co-leader of the study, said: “We have shown that when healthy people’s brains are exposed to a specific wavelength of infrared light for a short period of time, their memory And other neurological processes seem to have actually improved .
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Through homologous recombination, DNA repair requires a complex of BRCA2 and PP2A-B56
Time of Update: 2021-11-04
Today, we know that the gene and the protein BRCA2 encoded by BRCA2 play a key role in repairing certain types of DNA damage in cells .
Now, in a new study, researchers at the University of Copenhagen have shown that BRCA2 requires a special enzyme, PP2A-B56, to repair DNA damage .
