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On October 11, 2021, Molecular Nutrition & Food Research, an international academic journal in the field of nutrition, published an article “Improvement of non-alcoholic fatty liver disease in mice by intermittent use of a fasting-mimicking diet", the study used a mouse model to report that an intermittent diet regimen can effectively improve fatty liver
With the improvement of human nutritional conditions in modern life and the increase of obese people worldwide, the incidence of non-alcoholic fatty liver disease (Non-alcoholic fatty liver disease, referred to as fatty liver) is increasing
A doctoral student in Chen Yan's research group, Zhao Jingyu, and others used a high-fat and high-sucrose diet to establish a fatty liver model in mice, and analyzed the effect of intermittent dieting as a dietary intervention strategy on fatty liver
The study shows that intermittent dieting can improve various pathological states of fatty liver, and may achieve its intervention function by increasing the degradation of adipose tissue and promoting fatty acid oxidation in the liver, providing a new idea for clinical intervention in non-alcoholic fatty liver disease
Researcher Chen Yan from the Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences and Lu Qi from Tongji University School of Medicine are the co-corresponding authors of the paper, and Zhao Jingyu, a doctoral student at the Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences, is the first author of the paper
Article link: https://doi.