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PNAS never reported a point: the strange way phosphates interact with water
Time of Update: 2023-02-03
Dicalcium phosphate powderResearchers at the University of California, Santa Barbara and New York University (NYU) made a startling discovery when they directly investigated the mechanism of assembly of calcium-phosphate clusters: phosphate ions in water have a strange habit of spontaneously alternating between common hydration states and mysterious previously unreported "dark" states.
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A DNA swab solves the mystery of the origin of cancer
Time of Update: 2023-02-03
They developed a new software that accurately infers continental ancestry from tumor DNA and RNA.
They developed a new software that accurately infers continental ancestry from tumor DNA and RNA.
They developed a new software that accurately infers continental ancestry from tumor DNA and RNA.
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In real-world studies of 540,000 people, vaccines are more effective than antibodies produced by infection
Time of Update: 2023-02-03
In the study, researchers analyzed 540,000 participants aged 12-110 in the Indiana Patient Care Network (INPC) database between November 29, 2020 and February 9, 2022, 267847 of whom were vaccinated and the other half matched by the same number of COVID infections, comparing the effectiveness of vaccines with natural immunity in preventing all-cause death, hospitalizations, and emergency department visits.
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The global number of new crown sequelae is estimated to be nearly 145 million, and we must be vigilant against these "new crown sequelae" after "Yangkang"!
Time of Update: 2023-02-03
The results of the study showed that regardless of whether they were hospitalized or not, 45% of people who recovered from the new crown infection still had at least one persistent symptom during an average follow-up of 4 months, the most common symptoms being fatigue, sleep disturbance, pain/discomfort, and difficulty breathing.
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Yuan Jing's research group revealed the key molecules for malaria parasite morphological control and transmission of Anopheles malaria
Time of Update: 2023-02-03
On December 20, Yuan Jing's group published an online publication entitled "Apical anchorage and stabilization of subpellicular microtubules by apical polar ring ensures Plasmodium ookinete infection in mosquito" online in the journal Nature Communications Research papers.
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The flu vaccine can reduce stroke
Time of Update: 2023-02-03
Dr Michael Hill, a researcher at the Cumming Medical School (CSM) and principal investigator of the study, said: "We wanted to know if the vaccine had the same protective effect for those at risk of stroke.
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BBI: The team of Zhongda Hospital Affiliated to Southeast University discovered the reason why poor sleep hurts the brain!
Time of Update: 2023-02-03
Recently, Professor Ren Qingguo's team from the Department of Neurology, Zhongda Hospital Affiliated to Southeast University, published important research results online in the internationally renowned journal Brain, behavior, and immunity, they found that chronic SD can lead to intestinal dysbacteriosis, thereby activating the intestinal and brain NLRP3 inflammasomes, destroying the intestinal and blood-brain barriers, triggering the inflammatory response of the intestine and central nervous system (CNS), and then impairing cognitive function.
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Real-time follow-up radiation therapy can guarantee safer and more effective cancer treatment
Time of Update: 2023-02-03
By capturing and amplifying the tiny sound waves produced when X-rays heat human tissue, medical professionals can map the radiation dose in the body, providing them with new data to guide treatment in real time.
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Science Advances: Scientists discover the mechanism that plants use to control their mouths
Time of Update: 2023-02-03
The results were published in the journal Science Advances, "Stomatal CO2/bicarbonate sensor consists of two interacting protein kinases, Raf-like HT1 and non-kinase-activity activity requiring MPK12/MPK4。The researchers found that in a low-CO2 environment, a protein kinase called HT1 phosphorylates and activates the negative regulatory protein kinase CBC1 downstream, forcing guard cells on both sides of the stomata to swell and keep the stomata open for as long as possible to absorb carbon dioxide and meet the needs of photosynthesis.
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New software creates 3D nanostructures out of DNA to create miniature containers for delivering drugs
Time of Update: 2023-02-03
Science and Technology Daily Beijing, Dec. 27 (Reporter Zhang Mengran) According to the latest issue of Science Advances magazine, a new open-source software program developed by researchers at Duke
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Circulation: Cell reprogramming may reverse the body's heart fibrosis caused by a heart attack
Time of Update: 2023-02-03
Because adult cardiomyocytes have little ability to regenerate, resident cardiac fibroblasts synthesize extracellular mechanisms and form fibrosis after myocardial infarction (MI), leading to cardiac
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Integrative molecules reveal the specificity of Claudin 6 therapeutic antibodies for solid tumors
Time of Update: 2023-02-03
”9A1。 Integral Molecular, an industry leader in membrane protein antibody discovery, has released a targeting mechanism for its Claudin 6 (CLDN6) antibody ctm-76, which is being developed in collaboration with Context Therapeutics for cancer therapy.
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Science Advances: Proteins that may protect the heart in certain cancer treatment options
Time of Update: 2023-02-03
In two studies conducted on women undergoing breast cancer treatment, levels of a protein called hemagglutinin circulating in the blood were associated with increased cardiotoxicity.
In two studies conducted on women undergoing breast cancer treatment, levels of a protein called hemagglutinin circulating in the blood were associated with increased cardiotoxicity.
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Nature magazine selected 10 scientific figures: 31-year-old Chinese scientists were selected
Time of Update: 2023-02-03
”Original search: New crown predictor: Cao Yunlong, associate researcher of Peking University Biomedical Frontier Innovation Center and leading scientist of Beijing Changping LaboratoryCao Yunlong originally devoted himself to the research of single-cell genomics, but at the end of 2019, when he returned to China after graduating from Harvard University with a doctorate, he turned to virus research because of the arrival of the new crown epidemic.
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Nature Medicine: A number of different pathways are associated with the sequelae of the new crown
Time of Update: 2023-02-03
Researchers at the Icahn School of Medicine at Mount Sinai have published a study linking changes in blood gene expression during COVID-19 to the acute sequelae of SARS-CoV-2 infection.
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The role of macrophage PPARγ acetylation in determining adipose tissue remodeling was discovered for the first time
Time of Update: 2023-02-03
PPARγ synthesis activators thiazolidinediones (TZDs) are an important class of anti-diabetic drugs that inhibit the inflammatory response of macrophages and relieve adipose tissue inflammation in living organisms.
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PNAS: The study reveals the molecular basis of H3K9 methylation specific to the catalytic site of plant SUVH6 enzymes
Time of Update: 2023-02-03
This pathway interacts with the DNA methylation-mediated SUVH histone methyltransferase recruitment mechanism to enhance the deposition of H3K9me2 at specific chromatin sites.
This pathway interacts with the DNA methylation-mediated SUVH histone methyltransferase recruitment mechanism to enhance the deposition of H3K9me2 at specific chromatin sites.
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West China Hospital 70,000 people study, allergic constitution, not easy to be infected with the new crown
Time of Update: 2023-02-03
In the study, the researchers analyzed 70,557 participants in the UK Biobank database who completed COVID testing between March 16 and December 31, 2020, and divided the participants into 4 groups: allergic rhinitis group (3201), asthma group (8624), rhinitis and asthma group (1407), control group (57325), and the study analyzed the impact of allergic rhinitis or asthma on the risk, severity and mortality of new crown infection。
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"Nature Cancer": Radiotherapy + immunity, better effect! Scientists have also discovered new prognostic markers
Time of Update: 2023-02-03
Pitroda from the Division of Radiation and Cell Oncology at the University of Chicago designed and conducted a investigator-initiated Phase 1/2, randomized clinical trial (COSINR study) evaluating the safety and efficacy of concurrent or sequential radiotherapy in combination with ICB (ipilimumab and nivolumab) as first-line treatment for metastatic non-small cell lung cancer (NSCLC).
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Li Chuanyun's team proposed the "stowaway hypothesis" that new genes unique to humans originated from lncRNA, revealing the molecular basis of "why people are human"
Time of Update: 2023-02-03
What makes us uniquely human? In recent years, whether the origin of a new gene might serve as the genetic basis for a trait unique to humans that encodes higher human intelligence has become one of
