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Cell: A self-positioning brain circuit was found in zebrafish
Time of Update: 2023-02-03
html In a new study, researchers from the Howard Hughes Medical Institute in the United States show that a multi-regional brain circuit allows juvenile zebrafish to track where they are, where they have been, and how they return to their original location after displacement.
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Nature sub-issue: Self-assembled proteins that store cell "memory" and can be "viewed" using light microscopy
Time of Update: 2023-02-03
Edward Boyden, a researcher at the Howard Medical Institute and a member of MIT's McGovern Brain Institute and Koch Integrative Cancer Institute, said: "At the organ or body scale, there are many changes that occur over the course of hours to weeks and these changes cannot be tracked over time.
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Chinese scholars and overseas collaborators have made progress in the controllable preparation of perovskite quantum dot solid films
Time of Update: 2023-02-03
Figure: Perovskite quantum dot solid film strategy and constructed high-performance semiconductor device With the support of the National Natural Science Foundation of China (approval numbers: 91956130, 62104116, 22121005), the scientific research team led by researcher Yuan Mingjian and Professor Chen Jun of Nankai University and the team of Professor Edward H.
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Li Chuanyun's team proposed the "stowaway hypothesis" that new genes unique to humans originated from lncRNA, revealing the molecular basis of "why people are human"
Time of Update: 2023-02-03
What makes us uniquely human? In recent years, whether the origin of a new gene might serve as the genetic basis for a trait unique to humans that encodes higher human intelligence has become one of
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Nature magazine selected 10 scientific figures: 31-year-old Chinese scientists were selected
Time of Update: 2023-02-03
”Original search: New crown predictor: Cao Yunlong, associate researcher of Peking University Biomedical Frontier Innovation Center and leading scientist of Beijing Changping LaboratoryCao Yunlong originally devoted himself to the research of single-cell genomics, but at the end of 2019, when he returned to China after graduating from Harvard University with a doctorate, he turned to virus research because of the arrival of the new crown epidemic.
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The inner ear cells are arranged in a checkerboard shape that allows us to hear sound
Time of Update: 2023-02-03
essentialsIn the Corti organ of the inner ear, there are two types of cells arranged in a checkerboard-like mosaic pattern; Hair cells are responsible for hearing and support cells.
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Stanford develops the latest vaccine: 100 times more powerful than mRNA, covering all strains
Time of Update: 2023-02-03
Recently, scientists from Stanford developed a ferritin-based new crown nanoparticle vaccine that can produce powerful, long-lasting, broad-spectrum neutralizing antibodies in non-human primates.
Recently, scientists from Stanford developed a ferritin-based new crown nanoparticle vaccine that can produce powerful, long-lasting, broad-spectrum neutralizing antibodies in non-human primates.
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【Scientific Research News】Professor Li Zifu of the School of Life Sciences, Huazhong University of Science and Technology and Professor Sun Chaoyang of Tongji Hospital have made new progress in the direction of tumor targeted nanomedicine
Time of Update: 2023-02-03
On December 16, 2022, Professor Li Zifu, School of Life Sciences, Huazhong University of Science and Technology, National Engineering Research Center for Nanomedicine, and Professor Sun Chaoyang of Tongji Hospital co-published a title entitled "Acta Biomaterialia Codelivery of adavosertib and olaparib by tumor-targeting nanoparticles for augmented efficacy and reduced toxicity".
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The latest clinical data shows that the domestic new crown oral drug azvudine is safe and effective
Time of Update: 2023-02-03
The results of clinical studies have proved that azvudine can significantly shorten the nucleic acid conversion time, accelerate virus elimination, significantly reduce viral load, reduce symptoms and shorten the course of disease in patients with mild and moderate SARS-CoV-2 infection, and has good safety and no significant impact on liver and kidney function of patients, which is safe and effective.
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Challenging nutritionist perception: honey can improve key indicators of cardiometabolic health
Time of Update: 2023-02-03
In a systematic review and meta-analysis of clinical trials, researchers found that honey consumption was associated with lower fasting blood sugar, total and LDL cholesterol ("bad" cholesterol), triglycerides, and markers of fatty liver disease.
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"A life of strength" eggs, for the offspring, strive to repair radiation-damaged sperm DNA
Time of Update: 2023-02-03
Scientists have observed a 10-fold higher prevalence of childhood leukemia near the Sellafield nuclear power plant in the United Kingdom than in other regions, and a higher relative risk of non-Hodgkin lymphoma, particularly in children whose fathers had high radiation doses recorded before pregnancy.
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Hu Jiazhi's group and collaborators in the School of Life Sciences used Cas9TX to achieve efficient and safe gene editing in a mouse model of age-related macular degeneration
Time of Update: 2023-02-03
In the in vivo gene editing therapy model of age-related macular degeneration (AMD), this work quantitatively reveals for the first time the occurrence mode and frequency of chromosomal translocation and adeno-associated virus fragment insertion of CRISPR-Cas9 in the process of gene editing in vivo, and greatly reduces the production of these byproducts in the in vivo gene editing process by using the Cas9TX variant previously developed by the research group.
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Nature Cancer: Triple immunotherapy has the potential to treat pancreatic cancer
Time of Update: 2023-02-03
Researchers at the University of Texas MD Anderson Cancer Center have discovered a novel immunotherapy combination that targets checkpoints in T cells and myelosuppressor cells, successfully reprogrammed the tumor immune microenvironment (TIME), and significantly improved anti-tumor responses in preclinical models of pancreatic cancer.
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The University of California, Berkeley, has discovered that "viral toxins" can cause severe COVID-19
Time of Update: 2023-02-03
The study shows how part of the SARS-CoV-2 "spike" protein can disrupt cellular barriers inside blood vessels in body organs, such as the lungs, leading to so-called vascular leaks.
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Nature Aging: A therapy to remove senescent cells
Time of Update: 2023-02-03
JAX is poised to make a significant contribution to SenNet by analyzing senescent cells in the kidneys, placenta, pancreas and heart, as well as all tissues associated with chronic aging diseases.
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New evidence: Raising mitochondrial membrane potential is enough to slow down aging and prolong life! Research progress on mitochondria and aging mechanisms
Time of Update: 2023-02-03
" "Here, we show that the optogenetics of increasing mitochondrial membrane potential using photoactivated proton pumps in adulthood in nematodes can improve the age-related phenotype of Caenorhabditis elegans and extend their lifespan.
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Jiang Xinyi's team at Shandong University developed a drug delivery system based on Th17 cells that can be delivered across the blood-brain barrier to treat multiple sclerosis
Time of Update: 2023-02-03
In recent years, Professor Jiang Xinyi's team has made a series of important achievements in gene therapy and controlled delivery of nucleic acid drugs, which have been published in Nature Nanotechnology, Science Translational Medicine, Nature Communications, PNAS, Science Advances, Advanced Materials and other internationally renowned academic journals 。 Multiple sclerosis (MS) is an inflammatory autoimmune disease of the central nervous system (CNS), characterized by demyelinating, axonal damage, and neurodegeneration, for which there is currently no cure.
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Misfolded proteins in liver cells contribute to the development of liver cancer
Time of Update: 2023-02-03
"The findings suggest that gene therapy for hemophilia may increase the risk of liver cancer in some patients after years of treatment.
"The findings suggest that gene therapy for hemophilia may increase the risk of liver cancer in some patients after years of treatment.
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The novel protein domain plays an important role in photosynthetic system II assembly and angiosperm photoautotroph
Time of Update: 2023-02-03
com/retrieve/pii/S1674205222004518 Recently, Mo Xiaorong's research group from the Institute of Plant Biology, College of Life Sciences, Zhejiang University, published a report entitled " A novel protein domain is important for photosystem II complex assembly and photoautotrophic growth in angiosperms".
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Science sub-journal: A new target for advanced nonalcoholic fatty liver disease
Time of Update: 2023-02-03
Using the latest techniques — including monocytes sequencing of mouse and human liver tissue and advanced mouse 3D glass imaging to characterize critical scarring liver cells — researchers have discovered new drug candidate targets for the treatment of nonalcoholic fatty liver disease (NAFLD).
