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The Upstream and Downstream products of 5-Methoxy-1-[4-(trifluoromethyl)phenyl]-1-pentanone
Time of Update: 2023-04-30
These compounds are all synthesized through similar chemical reactions, involving the reaction of 4-trifluoromethylbenzene or 4-methoxyphenol with different acids.
These compounds are all synthesized through similar chemical reactions, involving the reaction of 4-trifluoromethylbenzene or 4-methoxyphenol with different acids.
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The Applications of Paliperidone palmitate
Time of Update: 2023-04-30
Additionally, paliperidone palmitate helps to improve the flow properties of the paint or coating, making it easier to apply and reducing the risk of brush marks and other imperfections.
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The Synthetic Routes of Paliperidone palmitate
Time of Update: 2023-04-30
The drug is synthesized through a series of chemical reactions that involve the synthesis of paliperidone and its esterification with palmitic acid.
The drug is synthesized through a series of chemical reactions that involve the synthesis of paliperidone and its esterification with palmitic acid.
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The Instruction of Sodium bromide
Time of Update: 2023-04-26
Following these guidelines can help ensure the safety of workers in the chemical industry and the environment Sodium bromide is a commonly used chemical in the chemical industry, particularly in the production of pharmaceuticals, agrochemicals, and other products.
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The Applications of Sodium bromide
Time of Update: 2023-04-26
Sodium bromide has a wide range of applications in the chemical industry, including as a reagent in the production of other chemicals, a catalyst in chemical reactions, and as a preservative in pharmaceuticals and other products.
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The Synthetic Routes of Sodium bromide
Time of Update: 2023-04-26
The synthetic routes for producing sodium bromide are many and varied, with different methods being used depending on the desired purity and intended use of the final product.
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The Upstream and Downstream products of Sodium bromide
Time of Update: 2023-04-26
Challenges in the Production of Sodium BromideThe production of Sodium Bromide involves several challenges, including the purification of raw materials, the control of reaction conditions, and the recovery and recycling of by-products.
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The Production Process of Sodium bromide
Time of Update: 2023-04-26
Sodium bromide is an important chemical compound used in various industrial and commercial applications, including as a flocculant in water treatment, as a fire retardant, and in the production of bromine and other halogen compounds.
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The Safety of Sodium bromide
Time of Update: 2023-04-26
In addition to proper labeling, storage, and PPE, there are other safety measures that are taken to ensure the safe handling and use of sodium bromide.
In addition to proper labeling, storage, and PPE, there are other safety measures that are taken to ensure the safe handling and use of sodium bromide.
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Neuron Ma Qiufu's lab discovered spinal cord pathways that selectively transmit affective visceral pain
Time of Update: 2023-02-03
On December 29, 2022, Professor Ma Qiufu and his postdocs Qi Lu and Lin Xinghong published an article in Neuron Spinal VGLUT3 lineage neurons drive visceral mechanical allodynia but not sensitized Viscero motor reflexes, which studies visceral pain from the intestines.
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Vertigo that may be caused by a viral infection? Pay attention to the choice of treatment plan...
Time of Update: 2023-02-03
Don't ignore this comorbidity!Check the diagnosis and treatment plan, how "6" is "Medical Knowledge Source"?
Don't ignore this comorbidity!Vertigo and dizziness only considered vestibular lesions?
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Scientists have confirmed for the first time that the "human-mouse brain" has a functional connection, and organoid research has gone further!
Time of Update: 2023-02-03
▲ Human brain organoids and microelectrodes were implanted into the brains of mice for recording (Image source: Reference [1]) When the researchers applied visual stimulation to mice with white light, they found that according to the neuroelectrical activity recorded by the electrodes, Human brain organoids share the same electrical activity patterns as the rat brain tissue around them.
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Diabetes Care: SGLT2 inhibitors reduce the risk of dementia in people with type 2 diabetes
Time of Update: 2023-02-03
▲Weighted Kaplan-Meier curves of subjects using SGLT2 and DPP-4 inhibitors (Image source: Reference [1])Overall, this large population-based cohort study showed a clinically significant association between SGLT2 inhibitor use and a lower risk of dementia at an average follow-up of 2.
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NBT(IF=68) Li Yulong's team at Peking University developed a highly sensitive and spatiotemporal resolution oxytocin release sensor
Time of Update: 2023-02-03
On January 2, 2023, Li Yulong's research group of Peking University published a report entitled "A genetically encoded sensor measures temporal oxytocin release from different neuronal compartments" in the journal Nature Biotechnology This study developed a highly sensitive GPCR activation-based (GRAB) sensor, GRABOT1.
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Nature Medicine: Professor Xu Yong antipsychotropic target receptor mediates the occurrence of obesity
Time of Update: 2023-02-03
1038/s41591-022-02106-5The images in the article are from references13 rare mutations in the gene encoding the 5-HT 2C receptorFigure 2: F327L mutant mice promote obesity in miceFigure 2: F327L mutant mice promote obesity in miceAfter further knocking the 5-HT2CR-F327L mutant into mice (referred to as F327L mutant mice) through CRISPR-Cas9 technology, even after the ordinary diet, excessive feeding, weight gain, fat and fat increase.
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Nature Metabolism: Professor Xu/Liu Feng's team revealed that hypothalamic junction protein enhances leptin signaling to promote weight loss
Time of Update: 2023-02-03
Figure 1: Knocking out Grb10 on AgRP neurons promotes obesity2Increasing Grb10 in POMC neurons enhances leptin sensitivityImmunofluorescence experiments showed that almost all (95%) POMC neurons expressed Grb10, and after specifically reducing Grb10 on arcuate POMC neurons through genetic tools, it did not cause changes in energy metabolism in ordinary diet, but after high-fat diet, it could significantly accelerate weight gain, fat gain, increased serum leptin and insulin levels, and reduced energy expenditure in mice.
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The team of Professor Tang Yamei of Sun Yat-sen University at Neuron discovered a new mechanism by which microglia infiltrate the brain parenchyma through chemotaxis peripheral CD8+ T cells
Time of Update: 2023-02-03
On January 5, 2023, Professor Tang Yamei's team from the Brain Science Research Center of Sun Yat-sen Memorial Hospital of Sun Yat-sen University published a report entitled "Microglia drive transient insult-induced brain injury by chemotactic recruitment of CD8+T" on Nelon lymphocytes" research paper elucidates the mechanism by which microglia secrete chemokines CCL2 and CCL8 after radiation attract CD8+ T cells to infiltrate brain tissue and cause brain damage, and propose new intervention strategies for the treatment of radiation brain injury.
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Neurointerventional treatment with uncontrollable perioperative blood pressure? Big coffee teaches you how to shoot
Time of Update: 2023-02-03
Although the effect of interventional treatment is good, perioperative blood pressure management is still indispensable due to changes in social environment and changes in living habits, coupled with hypertension, hyperlipidemia, Under the influence of major risk factors such as hyperglycemia, cerebrovascular diseases have occupied the first cause of death in China in recent years [1].
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Pay attention to "orthostatic intolerance after stroke", these 4 points to know!
Time of Update: 2023-02-03
Patient examination dataCase 783-year-old male, limb weakness, shaking for more than 1 month, symptoms appear when upright, lying flat can be relieved; History of previous hypertension and stroke, mRS score of 3 before admission.
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2022 Neurology Clinical Foundation Good Article Summary|Year-end Inventory
Time of Update: 2023-02-03
Year-end inventory ☟☟☟of the top 12 classic cases of neurology in 2022 to help you develop clinical thinkingIllustrated | 8 pictures teach you to master the basic skills➤Should know: The 5 most common central causes of dizzinessMultiple sclerosisMultiple sclerosisMultiple sclerosisMultiple sclerosis is a chronic, immune-mediated central nervous system disorder characterized by inflammation, demyelinating, and eventually axon loss.
