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Warby Medical and the China Cerebrovascular Disease Specialist Alliance reached a strategic cooperation to collaborate on stroke...
Time of Update: 2021-05-23
On May 15, 2021, at the "2021 China Stroke Conference" sponsored by the National Health Commission’s Stroke Prevention and Treatment Engineering Committee (Brain Prevention Committee), Shanghai Woby Medical and the China Cerebrovascular Disease Specialist Alliance signed a memorandum of cooperation and reached Strategic partnership.
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After PROTAC: Looking forward to a breakthrough in lysosomal degradation technology
Time of Update: 2021-05-23
Targeted protein degradation (TPD) technology uses two naturally occurring protein degradation systems in cells, namely Ubiquitin-proteasome system (UPS) and lysosomal degradation pathways to achieve disease-related The specific and efficient degradation of protein can achieve the effect of disease treatment.
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The intern administered anesthesia and failed to inform the patient that the hospital was claimed for 480 thousand
Time of Update: 2021-05-23
The judicial appraisal opinion believes that Hospital A has not fulfilled its diagnosis and treatment obligations corresponding to the medical level at the time; the writing of medical records is not standardized; traffic accidents and hospital A’s careless operation in the diagnosis and treatment process are the reasons for Zhang’s damage.
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It can hurt your brain without getting into the brain!
Time of Update: 2021-05-22
Researchers analyzed the autopsy results of 41 patients who died in the hospital due to the new crown and found that the complete viral RNA sequence could not be detected in the patient's brain At the same time, a large number of pathological changes were observed, which may explain why patients with new coronary disease have a variety of mental and neurological diseases.
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"Nature" Sub-Journal: Scientists first discovered that food smell and related olfactory nerves are involved in the regulation of dietary restriction and longevity process|Science Discovery
Time of Update: 2021-05-22
Through genetic modification technology and RNA interference technology, the researchers found that the olfactory circuit sends a signal to the intestine to regulate the energy sensor AMPK to inhibit diet and limit the lifespan of nematodes, thus indicating that the brain-gut signal axis plays a role in this process.
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Exclusive | Can gene editing and oligonucleotides reverse the development process of Huntington's disease?
Time of Update: 2021-05-22
▎Editor's note from WuXi AppTec's content team: According to estimates by the World Health Organization, there are currently 6000-8000 rare diseases in the world, affecting the lives of up to 400 million patients.
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A 71-year-old man with horizontal gaze paralysis, loss of speech ability, and quadriplegia, this disease must be thought of | Clinical Reasoning
Time of Update: 2021-05-22
Figure 1B 1 month after the first CT, MRIT2/FLAIR of the head showed that bilateral cerebellar midfoot lesions extended to the junction of the cerebellum, pons, and pontine, with extensive abnormal high signal; these areas also have limited diffusion and no enhancement (Not shown).
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Women with a history of preeclampsia have a 3.8 times higher risk of stroke in later life
Time of Update: 2021-05-22
Recently, researchers from the University of Utah Neurosciences analyzed data from the Framingham Heart Study (FHS) and found that women with a history of preeclampsia are more likely to have a stroke in later life.
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Baxter's nerve compression imaging performance
Time of Update: 2021-05-22
The enhanced scan occurs in the acute to subacute stage of denervation; in the case of Baxter nerve compression, according to the patient’s innervation anatomy, muscle edema will be selectively in the abductor digitorum (AbDM) occurs internally, and may also occur in the flexor digitorum brevis and quadratus plantar muscles; obvious muscle atrophy and fatification can be seen in the chronic phase.
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Do you know that these 6 diseases may be misdiagnosed as stroke?
Time of Update: 2021-05-22
CT of emergency stroke showed focal lesions on the left side, cortical curve enhanced, blood volume and blood flow increased focally (white arrow), and showed normal to rapid perfusion transit time.
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Advances in research on the neural loop mechanism of flexible classification decision
Time of Update: 2021-05-22
Finally, in order to further verify whether the orbitofrontal lobe-auditory cortex feedback loop actually performs the calculation function of inferring the category boundary line based on the task structure, the researchers used two-photon in-vivo calcium imaging to project the neuron axis from the orbital frontal lobe to the auditory cortex.
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7 cases, take you to a comprehensive understanding of multiple sclerosis|Clinical practice
Time of Update: 2021-05-22
Question 2 As shown in the figure below, MRI shows that the patient's right occipital radiation crown has asymptomatic enhanced lesions.
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The latest five types of cranial nerve multiple sclerosis, clinically necessary!
Time of Update: 2021-05-22
The research team from Italy used MRI to determine 5 cognitive phenotypes in a horizontal study of 1212 multiple sclerosis patients and 196 healthy controls through cognitive assessment methods, each of which has With specific clinical and attributed magnetic resonance imaging characteristics, it provides new ideas for clinical diagnosis!
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Science: The molecular mechanism of PCDH19 gene mutations causing synaptic dysfunction in female Dravet syndrome
Time of Update: 2021-05-22
On April 16, 2021, Hisashi Umemori's research team at Harvard Medical School's Boston Children's Hospital published an article in Science, revealing the previously undiscovered molecular mechanism of cognitive dysfunction caused by mutations in the PCDH19 gene.
This indicates that Pcdh19-HET female mice have obstacles in the presynaptic structure of mossy fibers during development.
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The "blocker" of AD treatment (2): The rebellious microglia phagocytic function promotes the pathological changes of AD
Time of Update: 2021-05-22
TAM-mediated microglia phagocytosis promotes the formation of amyloid plaques.
This means that the function of phagocytosis and deposition of plaques mediated by TAM signaling microglia instead promotes the formation of plaques.
TAM-mediated microglia phagocytosis of amyloid plaques does not inhibit the formation of plaques.
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Nature: Why do you gain so much weight after marriage?
Time of Update: 2021-05-22
This study found that the reason why fruit flies increase their food intake during reproduction is due to changes in the activity of neurons that "talk" to the intestine.
"After female fruit flies mate, the intestinal neuron-mediated "crop" enlargement increases food intake.
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Wang Minzhong: Treatment of Patients with Depression and Anxiety in Department of Neurology——Using "Real First-line Drugs" to Help Patients "Reassure" | Big Coffee Interview · Issue 2
Time of Update: 2021-05-22
Introduction Patients with depression and anxiety are often first diagnosed in the Department of Neurology. Clinicians have certain differences when treating such patients: some doctors tend to choo
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Nature Sub-Journal: Aspirin can improve the cognitive dysfunction of elderly men caused by air pollution
Time of Update: 2021-05-22
On May 3, 2021, the Gao Xu team from the School of Public Health of Peking University published a report titled: Short-term air pollution, cognitive performance and nonsteroidal anti-inflammatory drug use in the Veterans Affairs Normative Aging Study in the Nature Aging journal research paper.
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Hypoglycemia causes refractory epilepsy?
Time of Update: 2021-05-22
It can be seen that the main manifestations of this patient are pituitary prolactinoma, insulinoma, and parathyroid adenoma, which is consistent with multiple endocrine neoplasia type 1 (MEN-1).
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Consensus on the diagnosis and treatment of central nervous system infections released, a quick overview of the main points!
Time of Update: 2021-05-22
Recommendations: ➤ For patients with high suspicion of intracranial infection, CT or MRI is recommended to assist in diagnosis and treatment (medium level, strong recommendation).
