Women with a history of preeclampsia have a 3.8 times higher risk of stroke in later life

Pregnancy hypertension is the symptoms of hypertension, edema, proteinuria and other symptoms in women after 20 weeks of pregnancy, which are transient and disappear after childbirth.

Hypertension in pregnancy is a disease specific to pregnancy.
It is currently one of the main causes of morbidity and death of pregnant women and perinatal children, and increases the risk of cardiovascular, cerebrovascular and kidney diseases.

Preeclampsia, in a broad sense, refers to new-onset hypertension during pregnancy with damage to internal organs.
It is a common hypertensive disorder of pregnancy, which occurs in 8% of pregnancy.

Previous studies have shown that pre-eclampsia can lead to acute cerebrovascular complications, including stroke and intracranial vascular disease.

However, the existing research does not fully study the risk of stroke in later life in women who have had preeclampsia.

Recently, researchers from the University of Utah Neurosciences analyzed data from the Framingham Heart Study (FHS) and found that women with a history of preeclampsia are more likely to have a stroke in later life.

In this study, the researchers conducted a secondary analysis based on data from the Framingham Heart Study conducted from 1948 to 2016.

The analysis sample included a total of 1,435 women, with an average age of 44.
4 years, and all of them were white.

Researchers collect data on participants' vascular risk factors, history of preeclampsia, and stroke incidence every six months, with a follow-up period of 32 years.

The results of Pixabay showed that during the follow-up, 169 women had a history of preeclampsia and 231 women had strokes.

At baseline, women with preeclampsia are more likely to be younger, receiving cholesterol-lowering drugs, lower cholesterol and higher diastolic blood pressure, and smoking habit.

After adjusting for vascular risk factors, the researchers found that compared with women without a history of preeclampsia, women with a history of preeclampsia were about 3.
8 times more likely to develop a stroke later in life.The relationship between pre-eclampsia and stroke risk.
Researchers said, “Pre-eclampsia is a complex disease that involves damage to the lining of blood vessels.
In the
past, it was thought that pre-eclampsia disappeared after childbirth, but pre-eclampsia may be affected.
Blood vessels cause lasting damage.

After adjusting for confounding factors that change over time, we found that preeclampsia in white women is associated with a significant increase in the long-term risk of stroke.
As
with all observational studies, it cannot be due to unmeasured confounding factors.
Determine the cause and effect relationship, and the research results cannot be generalized to non-white races or ethnic groups.
In the
future, more large-scale and more studies are needed to explore the relationship between the two in depth.
"
Original Source Adam de Havenon, MD1; Alen Delic, MS1; Eric Stulberg, MD, MPH1; et al.
Association of Preeclampsia With Incident Stroke in Later Life Among Women in the Framingham Heart Study.
JAMA Network Open (2021).
DOI: 10.
1001 /jamanetworkopen.
2021.
5077