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Sub-Journal of "Cell": Recovery after stroke depends on immunotherapy!
Time of Update: 2021-06-01
A recent study by Chinese scientists may point to a feasible direction: The team of Assistant Professor Hu Xiaoming (transliteration) from the University of Pittsburgh found that regulatory T cells that infiltrate the brain within a few weeks after a stroke can repair the white matter of the brain Has a key role, thereby affecting the rehabilitation of neurological function and the long-term prognosis of patients.
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JAMA: Continuous hypertonic fluid therapy is not beneficial to neurological function improvement in patients with traumatic brain injury
Time of Update: 2021-06-01
In patients with moderate to severe traumatic brain injury, continuous infusion of 20% hypertonic saline has no significant difference in neurological improvement at 6 months compared with standard treatment.
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Nature Sub-Journal: Nanke Datian Ruilin and others found a new mechanism of neuronal iron death
Time of Update: 2021-06-01
This study investigated the regulation of neuronal oxidative stress through a large-scale CRISPR screening system, and clarified a new mechanism of neuronal iron death caused by PSAP-involved lysosomal lipid metabolism disorder.
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American College of Cardiology (ACC): The most cost-effective way to prevent cardiovascular disease, why not try it soon?
Time of Update: 2021-06-01
html">sleeping less than 6 hours a night is associated with the occurrence of myocardial infarction, stroke, and increased risk of death from atherosclerosis.
html">sleeps less than 6 hours per night, which is related to the occurrence of myocardial infarction, stroke, and the increased risk of death from atherosclerosis.
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Neuron | Mei Lin/Xiong Wencheng's group reveals a new mechanism of postsynaptic receptor aggregation and neuromuscular junction formation
Time of Update: 2021-06-01
Aggregin, Lrp4, Musk or Rapsn mutant mice cannot form acetylcholine receptor aggregates and neuromuscular junctions; their genetic mutations can cause congenital myasthenia, while patients with myasthenia gravis have anti-aggregin, Lrp4 or/ And Musk's antibodies, all of which indicate that these protein molecules play a very important role in the formation and function of neuromuscular junctions.
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J Neurol Neurosur Ps: Factors Influencing the Risk of Relapsing and Progressive Multiple Sclerosis
Time of Update: 2021-06-01
com/content/early/2021/05/13/jnnp-2020-325688-0" target="_blank" rel="noopener">Factors affecting the risk of relapsing-onset and progressive-onset multiple sclerosis .
com/content/early/2021/05/13/jnnp-2020-325688-0" target="_blank" rel="noopener">Factors affecting the risk of relapsing-onset and progressive-onset multiple sclerosis leave a message here
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Stroke: Increased risk of stroke in patients with obsessive-compulsive disorder
Time of Update: 2021-06-01
do?w=%E5%BF%83%E8%A1%80%E7%AE%A1">Heart blood vesselsThe researchers determined the occurrence of ischemic (ICD-9-CM codes: 433, 434, and 435) and hemorrhagic (ICD-9-CM codes: 430, 431, and 432) strokes during the follow-up period (from enrollment to the end of 2011) In addition, the researchers evaluated the effects of drugs used to treat obsessive-compulsive disorder.
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How should a 47-year-old man develop multiple cranial nerve palsy and dural enhancement?
Time of Update: 2021-06-01
The patient's sudden onset, worsening of Valsalva's movements, and related neurological symptoms indicate a secondary headache.
MRI of the head showed thickening of the right dura mater and enhanced meninges of the cerebellopontine angle (Figure 1A and B); no substantial lesions, and normal angiography.
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JNNP: The circadian rhythm of the onset and progression in the central ischemic stroke area
Time of Update: 2021-06-01
This article uses a meta-analysis of data from three independent and prospectively recruited cohorts of pre-LVO stroke patients to explore whether the ischemic side central area and penumbra volume show around 24 hours The ("circadian rhythm") rhythm.
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Nat Med: Clinical use of optogenetic methods to partially restore vision in blind patients
Time of Update: 2021-06-01
gov clinical number: NCT03326336)Recently, in a blind patient, researchers combined intraocular injection of an adeno-associated virus vector encoding ChrimsonR with light stimulation through engineered goggles.
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Various types of eye movement disorders lesions and common causes|Knowledge Card
Time of Update: 2021-06-01
In 2019, the editor launched the "Knowledge Cards" column, which organizes some clinical disease-related knowledge points in a simple and easy-to-save table format, so that clinicians can use the fragmented time to review the past and learn.
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BMJ: Ischemic stroke may occur after COVID-19 vaccination, but COVID-19 infection itself is more common
Time of Update: 2021-05-31
As COVID-19 related vaccine induces immunity of thrombotic thrombotic complications thrombocytopenia (Vitt) may comprise a portion of the occurrence of ischemic stroke and cerebral venous thrombosis.
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Nat Commun: Identification of age-related genetic modifiers in X-linked dystonia-Parkinson's disease
Time of Update: 2021-05-31
In X-linked dystonia-Parkinson's disease, there are three potential age-related regulatory factors that affect the DNA mismatch repair pathway.
In X-linked dystonia-Parkinson's disease, there are three potential age-related regulatory factors that affect the DNA mismatch repair pathway.
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npj Parkinson's Disease: Non-invasive vagus nerve stimulation can improve clinical and molecular biomarkers in patients with Parkinson's disease with gait freezing
Time of Update: 2021-05-31
Non-invasive vagus nerve stimulation improves clinical and molecular biomarkers of Parkinson's disease in patients with freezing of gait.
Non-invasive vagus nerve stimulation improves clinical and molecular biomarkers of Parkinson's disease in patients with freezing of gait.
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Alzheimer's Research & Therapy: Aging-related blood-borne factors may be biomarkers of preclinical AD cognitive ability
Time of Update: 2021-05-31
Senescence-related blood-derived factors associated with hippocampal dysfunction, including THBS4, GDF11 and CCL11, may be ideal biomarkers for accelerating long-term forgetting .
Blood-derived factors related to aging and hippocampal dysfunction, including THBS4, GDF11 and CCL11, may be ideal biomarkers for accelerating long-term forgetting.
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npj Parkinson's Disease: Early constipation indicates a faster onset of Parkinson's disease dementia
Time of Update: 2021-05-31
The results of this study support the importance of studying constipation in PD patients, indicating that the appearance and severity of constipation symptoms at the time of diagnosis can predict subsequent dementia progression.
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ACS Chem Neuro: Polymeric estrogen has the effect of protecting nerves
Time of Update: 2021-05-23
March 21, 2021 //---According to a recent study, a new type of polymeric estrogen developed by the Rensselaer Institute can provide neuroprotection when implanted in the spinal cord injury site, thereby preventing further damage.
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Biogen Fampridine Sustained-Release Tablets are approved to improve the walking ability of adult patients with multiple sclerosis...
Time of Update: 2021-05-23
On May 14, 2021, Bojian Company announced that Fampridine Sustained-Release Tablets have been officially approved by the National Medical Products Administration for the improvement of multiple sclerosis (hereinafter referred to as MS) combined with walking disorder (EDSS score 4-7) in adult patients Walking ability.
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Eli Lilly and MiNA develop a new drug based on the saRNA platform, Bojian and Ca...
Time of Update: 2021-05-23
On May 11, Eli Lilly and MiNA Therapeutics, an RNA activation therapy company, announced a global research collaboration to develop new drug candidates using MiNA's proprietary small molecule activated RNA (saRNA) technology platform.
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Warby Medical and the China Cerebrovascular Disease Specialist Alliance reached a strategic cooperation to collaborate on stroke...
Time of Update: 2021-05-23
On May 15, 2021, at the "2021 China Stroke Conference" sponsored by the National Health Commission’s Stroke Prevention and Treatment Engineering Committee (Brain Prevention Committee), Shanghai Woby Medical and the China Cerebrovascular Disease Specialist Alliance signed a memorandum of cooperation and reached Strategic partnership.
