-
Categories
-
Pharmaceutical Intermediates
-
Active Pharmaceutical Ingredients
-
Food Additives
- Industrial Coatings
- Agrochemicals
- Dyes and Pigments
- Surfactant
- Flavors and Fragrances
- Chemical Reagents
- Catalyst and Auxiliary
- Natural Products
- Inorganic Chemistry
-
Organic Chemistry
-
Biochemical Engineering
- Analytical Chemistry
-
Cosmetic Ingredient
- Water Treatment Chemical
-
Pharmaceutical Intermediates
Promotion
ECHEMI Mall
Wholesale
Weekly Price
Exhibition
News
-
Trade Service
Air pollution, especially fine particulate matter (PM2.
5), has always been considered a major global public health problem.
PM2.
5 refers to the particulate matter in the ambient air with an aerodynamic equivalent diameter less than or equal to 2.
5 microns.
It can be suspended in the air for a longer time, and the higher its concentration in the air, the more serious the air pollution.
Compared with the coarser atmospheric particulate matter, PM2.
5 has a small particle size, a large area, strong activity, easy to carry toxic and harmful substances (for example, heavy metals, microorganisms, etc.
), and has a long residence time in the atmosphere and a long transportation distance.
Therefore, it has a greater impact on human health and the quality of the atmospheric environment.
Cognitive decline is common in the elderly, and environmental factors can accelerate this decline, such as exposure to fine particulate matter (PM2.
5) in the air that does not exceed 2.
5 microns in size.
Nevertheless, there is still a lack of research on the impact of short-term air pollution exposure on the cognitive function of the elderly.
Previous studies have shown that non-steroidal anti-inflammatory drugs (a class of drugs that relieve pain and inflammation, such as aspirin) can be used as a potential treatment for cognitive dysfunction and dementia.
However, it has never been studied before whether non-steroidal anti-inflammatory drugs can be used as an intervention for the impact of air pollution on cognitive health.
On May 3, 2021, the Gao Xu team from the School of Public Health of Peking University published a report titled: Short-term air pollution, cognitive performance and nonsteroidal anti-inflammatory drug use in the Veterans Affairs Normative Aging Study in the Nature Aging journal research paper.
The paper pointed out that short-term exposure (up to 28 days) to high levels of air pollution is related to cognitive dysfunction in older men.
The study also found that among the subjects taking common non-steroidal anti-inflammatory drugs, the negative effects of this short-term air pollution exposure were relatively minor.
In September 2019, Gao Xu's team published a research paper titled: Nonsteroidal Anti-Inflammatory Drugs Modify the Effect of Short-Term Air Pollution on Lung Function in the American Journal of Respiratory and Critical Care Medicine (AJRCCM).
This study proved for the first time that non-steroidal anti-inflammatory drugs, especially aspirin, can reduce the adverse effects of short-term air pollution exposure on lung function, and have a preventive effect on the adverse effects of air pollution on lung function.
In the Nature Aging paper, Gao Xu and others studied 954 elderly white men (average age 70) in the Greater Boston area who participated in the Veterans Affairs Normative Aging Study in the United States.
In multiple visits, the cognitive performance of these people was evaluated using the general cognitive function and the Mini Mental State Examination (MMSE) score.
These data were then compared with the local PM2.
5 level on the day of each visit and the average PM2.
5 level 1-4 weeks before the visit.
The comparison found that the increase in PM2.
5 levels up to 28 days before the evaluation is related to the decline in the participants' overall cognitive function scores, even if the PM2.
5 level is lower than the level generally considered dangerous (approximately ≤10 μg/m3).
They also found that the subjects taking non-steroidal anti-inflammatory drugs were less adversely affected by short-term air pollution exposure.
The research team said that interdisciplinary studies based on larger cohorts and more detailed information on the use of non-steroidal anti-inflammatory drugs are still needed to verify the relationship between air pollution exposure and cognitive function, as well as non-steroidal anti-inflammatory drugs.
The possible improvement effect on this. Link to the paper: Open Reprint This article Open Reprint: In this article Just leave a message
5), has always been considered a major global public health problem.
PM2.
5 refers to the particulate matter in the ambient air with an aerodynamic equivalent diameter less than or equal to 2.
5 microns.
It can be suspended in the air for a longer time, and the higher its concentration in the air, the more serious the air pollution.
Compared with the coarser atmospheric particulate matter, PM2.
5 has a small particle size, a large area, strong activity, easy to carry toxic and harmful substances (for example, heavy metals, microorganisms, etc.
), and has a long residence time in the atmosphere and a long transportation distance.
Therefore, it has a greater impact on human health and the quality of the atmospheric environment.
Cognitive decline is common in the elderly, and environmental factors can accelerate this decline, such as exposure to fine particulate matter (PM2.
5) in the air that does not exceed 2.
5 microns in size.
Nevertheless, there is still a lack of research on the impact of short-term air pollution exposure on the cognitive function of the elderly.
Previous studies have shown that non-steroidal anti-inflammatory drugs (a class of drugs that relieve pain and inflammation, such as aspirin) can be used as a potential treatment for cognitive dysfunction and dementia.
However, it has never been studied before whether non-steroidal anti-inflammatory drugs can be used as an intervention for the impact of air pollution on cognitive health.
On May 3, 2021, the Gao Xu team from the School of Public Health of Peking University published a report titled: Short-term air pollution, cognitive performance and nonsteroidal anti-inflammatory drug use in the Veterans Affairs Normative Aging Study in the Nature Aging journal research paper.
The paper pointed out that short-term exposure (up to 28 days) to high levels of air pollution is related to cognitive dysfunction in older men.
The study also found that among the subjects taking common non-steroidal anti-inflammatory drugs, the negative effects of this short-term air pollution exposure were relatively minor.
In September 2019, Gao Xu's team published a research paper titled: Nonsteroidal Anti-Inflammatory Drugs Modify the Effect of Short-Term Air Pollution on Lung Function in the American Journal of Respiratory and Critical Care Medicine (AJRCCM).
This study proved for the first time that non-steroidal anti-inflammatory drugs, especially aspirin, can reduce the adverse effects of short-term air pollution exposure on lung function, and have a preventive effect on the adverse effects of air pollution on lung function.
In the Nature Aging paper, Gao Xu and others studied 954 elderly white men (average age 70) in the Greater Boston area who participated in the Veterans Affairs Normative Aging Study in the United States.
In multiple visits, the cognitive performance of these people was evaluated using the general cognitive function and the Mini Mental State Examination (MMSE) score.
These data were then compared with the local PM2.
5 level on the day of each visit and the average PM2.
5 level 1-4 weeks before the visit.
The comparison found that the increase in PM2.
5 levels up to 28 days before the evaluation is related to the decline in the participants' overall cognitive function scores, even if the PM2.
5 level is lower than the level generally considered dangerous (approximately ≤10 μg/m3).
They also found that the subjects taking non-steroidal anti-inflammatory drugs were less adversely affected by short-term air pollution exposure.
The research team said that interdisciplinary studies based on larger cohorts and more detailed information on the use of non-steroidal anti-inflammatory drugs are still needed to verify the relationship between air pollution exposure and cognitive function, as well as non-steroidal anti-inflammatory drugs.
The possible improvement effect on this. Link to the paper: Open Reprint This article Open Reprint: In this article Just leave a message
