-
"Science": It's the pot of the virus again!
Time of Update: 2022-01-24
At least a large number of serum samples have been tested to point to a possible suspect - EBV (Epstein-Barr virus), which belongs to the Herpesviridae family of lymphotropic viruses and specifically attacks B cells .
-
"Nature" deeply concerned: How has the brain development of children born during the epidemic been affected?
Time of Update: 2022-01-24
Prenatal Stress and Decline in Communication Skills Some pediatric experts at New York-Presbyterian Morgan Stanley Children's Hospital have been focusing on infant neurodevelopment since before the pandemic, especially the development of communication and motor skills during the first six months of life .
-
FDA Approves Mannat Sodium Capsules (Nine Phase One®) for International Phase II Clinical Trial of Parkinson's Disease
Time of Update: 2022-01-24
On this basis, the research team carried out a preclinical study on the treatment of Parkinson's disease based on the common pathological mechanism of neurodegenerative diseases, and found that the nine-phase one® can regulate the imbalance of intestinal flora and inhibit the α-synapse Aggregation of nucleoproteins, reducing α-synuclein deposition in the gut and brain, reducing neuroinflammation and protecting dopaminergic neurons, improving motor and non-motor symptoms .
-
NMDAR encephalitis and teratoma - fraternal or fraternal?
Time of Update: 2022-01-24
Brilliant eyes, each breakthrough ① Identification and diagnosis of combined ovarian teratoma and anti-NMDAR encephalitis Screening and identification are very important for early treatment to improve prognosis: In terms of clinical manifestations, patients often present with acute onset neuropsychiatric symptoms, and antipsychotic symptoms.
-
Why can't I keep playing with my phone... Maybe there's something wrong with this small group of cells
Time of Update: 2022-01-24
By comparing changes in pupil size and neural oscillatory signals, the researchers found that when the pupil is larger, the nucleus locus coeruleus is active .
-
STAR Protocols︱Min Zhao's research group proposes a new plan for physical intervention in methamphetamine use disorder psychological craving
Time of Update: 2022-01-24
On December 17, 2021, Zhao Min's research group from the Shanghai Mental Health Center published an experimental protocol article titled "A transcranial magnetic stimulation protocol for decreasing the craving of methamphetamine-dependent patients" in STAR Protocols, a sub-journal of Cell ( Protocol), proposed clinical intervention methods of DLPFC single target, VMPFC single target and dual target combined stimulation, and related works have also been published [4] .
-
Neurology: Long-term occupational exposure to formaldehyde increases the risk of cognitive impairment, and some cognitive impairment is irreversible for life
Time of Update: 2022-01-23
A study of 305 histology technicians between the ages of 23 and 78 showed that the number of hours of daily occupational exposure to formaldehyde was associated with better performance on tests assessing memory, dexterity, balance, coordination and reaction time.
-
Movement Disorder: Fudan Huashan Hospital, PET imaging reveals rare disease progression in frontotemporal dementia
Time of Update: 2022-01-23
from Fudan Huashan Hospital attempted to study the clinical utility of 18F-APN-1607 PET/CT in MAPT mutation carriers by analyzing 7 patient samples with different phenotypes .
18 F-APN-1607 PET/CT imaging is important for detecting tau accumulation in MAPT mutation carriers Original source: Zhou X, Lu J, Liu F, et al.
-
Age & Ageing Peking University: Trajectories of Depressive Symptoms and Subsequent Cognitive Decline in the Elderly
Time of Update: 2022-01-23
To investigate the relationship between different trajectories of depressive symptoms and subsequent rates of cognitive decline in older adults, experts from Peking University in China in conjunction with the Department of Psychiatry and Behavioral Sciences at Duke University Medical Center conducted a population-based cohort study and the results were published in Age & Ageing Magazine .
-
J CEREBR BLOOD FM: Relationship between venous cerebral blood flow quantification and cognition in patients with sickle cell anemia
Time of Update: 2022-01-23
The researchers aimed to quantify the effects and explore cross-sectional associations with arterial oxygen content (CaO2), disease-modifying treatments, silent cerebral infarction (SCI), and cognitive performance .
Using multiTI sequences in patients, increased CBF in white matter and hyperintense sagittal sinus regions was associated with poorer cognitive performance .
-
JAMA sub-journal: Stroke drug edaravone in the treatment of "ALS" patients is safe and reliable, but its efficacy is questionable
Time of Update: 2022-01-23
In order to evaluate the long-term safety and efficacy of intravenous edaravone in patients with ALS in a real clinical setting, experts from the Department of Neurology at the University of Ulm in Germany conducted a related study, and the results were published in the journal JAMA Neurology .
-
JNNP: How can ALS patients gain weight safely and effectively?
Time of Update: 2022-01-23
In 2018, our group concluded the Lipids and Calories in Patients with ALS (LIPCAL-ALS) study, a randomized, placebo-controlled, multicenter trial testing high cholesterol with 405 kcal and 45 g of fat in 200 patients.
-
JNNP: Development of a Novel Clinical Examination Scale for Measuring Creutzfeldt-Jakob Disease Severity
Time of Update: 2022-01-23
Longitudinal changes in motor and cognitive scales between first and second assessments Two validated, disease-specific, clinician-examined-based scoring scales were developed for patients with sCJD using the Rasch model, reflecting disease progression in the cognitive and motor systems .
-
Neuromodulation: A prospective, multicenter study evaluating the safety and efficacy of translingual nerve stimulation plus physical therapy for the treatment of chronic balance deficits caused by mild to moderate traumatic brain injury
Time of Update: 2022-01-23
In addition to headache, sleep quality, and frequency of falls, TLNS plus targeted PT also observed significant improvements in balance and gait; in participants with chronic balance deficits after mmTBI and who had been stable on prior conventional physical therapy .
-
Movement Disorder: How does the new drug Mevidalen treat dementia with Lewy bodies?
Time of Update: 2022-01-23
Blood vesselThe significance of this study is the discovery that: Mevidalen utilizes a novel mechanism of action to improve LBD-related motor symptoms in addition to standard of care , while improving or not exacerbating non-motor symptoms associated with traditional dopaminergic therapy .
-
Neurology: Diffusion tensor imaging along perivascular spaces (DTI-ALPS) reveals associations between lymphatic function and neuropsychology, gray matter volume, sleep: Sleep health has implications for brain health
Time of Update: 2022-01-23
"Diffusion Tensor Imaging Analysis Along Perivascular Space" (DTI-ALPS) Index DTI-Alps presents an opportunity for non-invasive studies of the human lymphatic system, using this method to assess the lymphatic system in a community-based non-demented elderly population with the aim of correlating lymphatic function with sleep, neuropsychological performance, and gray matter volume connection between .
-
Neurology: Pediatric stroke age is the key to long-term cognitive prognosis, and juvenile stroke (29 days-6 years old) has a great impact
Time of Update: 2022-01-23
Quality of life Recently, researchers examined long-term cognitive outcomes after stroke in children in the chronic phase (more than 2 years after stroke) and investigated whether age affects cognition in stroke to determine the risk of patients with poorer cognitive outcomes.
-
Frontiers Chinese scholars: Are you afraid of dementia?
Time of Update: 2022-01-23
To determine whether participation in leisure activities can prevent cognitive decline associated with APOE ε4, experts from Peking University and Sun Yat-Sen University in China conducted a cohort of the China Longitudinal Health and Longevity Survey .
-
Neurology CP: a case of giant cell arteritis
Time of Update: 2022-01-23
Doppler ultrasonography showed a hypoechoic halo sign along the facial artery, while PET-CT showed increased fluoro-18-fluorodeoxyglucose uptake along the vertebral artery and other larger arteries, leading to the diagnosis of giant cell arteritis (Figure 2) .
-
Neurology: Risk comparison of seizure exacerbation in different epilepsy types before and after pregnancy: focal epilepsy may be exacerbated, especially frontal lobe epilepsy
Time of Update: 2022-01-23
Among patients with focal epilepsy, seizure frequency increased in patients with frontal lobe epilepsy (OR 8.
Among patients with focal epilepsy, seizure frequency increased in patients with frontal lobe epilepsy (OR 8.
