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Age & Ageing Peking University: Trajectories of Depressive Symptoms and Subsequent Cognitive Decline in the Elderly

 Last Update: 2022-01-23
 Source: Internet
 Author: User

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Geriatric depression is a complex affective disorder, especially in patients with depression at the age of 60 and above

Depression in the elderly is highly coexisting with physical illness, and is often associated with cognitive impairment

Risk elderly with dementia associated with depressive symptoms significantly increased risk elderly with dementia associated with depressive symptoms significantly increased quality of life

The course of depression is variable, but how this variability affects long-term cognitive decline is unclear

The study sites were selected in communities in the United States and the United Kingdom

The results identified five trajectories of depressive symptoms

'Worsening of depressive symptoms' trajectory compared to 'non-depressed' trajectory (ensemble beta = -0.

CONCLUSIONS: Subthreshold depressive symptoms were associated with an increased rate of cognitive decline, whereas individuals with improved depressive symptoms did not exhibit accelerated cognitive decline

references:

Trajectories of depressive symptoms and subsequent cognitive decline in older adults: a pooled analysis of two longitudinal cohorts , Age and Ageing, Volume 51, Issue 1, January 2022, afab191, https://doi.

Trajectories of depressive symptoms and subsequent cognitive decline in older adults: a pooled analysis of two longitudinal cohorts

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