-
"Collector's Edition" Science Special Review on Inflammation (3) "Two-way Going" - Inflammatory Signal Transduction Based on the Gut-Brain Axis
Time of Update: 2022-08-15
Recent studies have shown that the gut-brain axis can regulate the immune homeostasis of the body by mediating inflammatory signal transduction, thus playing an important role in a variety of inflammatory diseases .
-
How to diagnose and treat mild cognitive impairment from Alzheimer's disease?
Time of Update: 2022-08-15
Non-drug treatment ➤Recommendation: (1) Non-drug interventions are recommended for AD-derived MCI patients, including cognitive training, moderate-intensity physical exercise, and reasonable diet (such as Mediterranean diet) (Class IIa recommendation, Level B evidence) .
-
JAMA: Professor Jiao Liqun's team from Xuanwu Hospital confirmed that endovascular treatment of symptomatic intracranial arterial stenosis has no benefit (CASSSISS study)
Time of Update: 2022-08-15
：JAMA、，。RESCUE BT，：JAMA：（RESCUE BT）。CASSISS，，，，。，！2015CHANCENEJM，！！
In the early morning of August 10, 2022, led by the team of Professor Jiao Liqun from the Department of Neurosurgery of Xuanwu Hosp
-
Nat Neurosci Demyelinated Neonatal Oligodendrocytes Have Greater Remyelination Ability
Time of Update: 2022-08-15
, Nat Neurosci, 2022) At the end of the article, the researchers also observed the ability of new OLs to form myelin sheaths Figure 6 Myelin-encapsulated cell bodies also exist in the brains of MS patients (Source: Neely et al.
-
Deadly Brain Cancer Attacks Faster?
Time of Update: 2022-08-15
https://——List of recent popular events——▼May 24, Agilent Cell and Gene Therapy Webinar Series - Phase 2▼May 25, 2022 Pall Gene Therapy Series Live - Phase 1: ▼June 1, Considerations on Release Criteria for Gene Therapy--Gene Editing Off-target Detection and verify May 24, 2022 / eMedClub News / -- Glioblastomas (GBMs) are fast-growing gliomas, malignant grade 4 tumors that account for about 15% of all brain tumors, and are There are about 290,000 new patients worldwide .
-
JAMA: Intravenous tirofiban before endovascular therapy does not significantly improve clinical outcomes in patients with large vessel occlusive stroke (RESCUE BT study)
Time of Update: 2022-08-15
Coronary Syndrome Diagnosis and StrokeA multicenter, randomized, placebo-controlled, double-blind clinical trial of intravenous tirofiban before endovascular therapy for acute large vessel occlusion (RESCUE BT) was conducted by the Department of Neurology, Second Affiliated Hospital of Army Medical University (Chongqing Xinqiao Hospital) The team of Professor Yang Qingwu and Professor Zi Wenjie of the Medical Center cooperated with 54 hospitals across the country.
-
Lack of sleep as a child leads to "social fear" when growing up... New research reveals the neural mechanism by which adolescents' lack of sleep affects social behavior
Time of Update: 2022-08-12
The system cannot respond in a timely and effective manner to emerging social stimuli Not only that, projections from the VTA to the NAc were abnormally enhanced in the brains of these mice, suggesting that sleep disturbance during adolescence may have affected the wiring and refinement of dopaminergic neurons during development, leading to dopaminergic dopaminergic neurons in adulthood.
-
JPD: Personality test, helpful for basic classification of Parkinson's disease
Time of Update: 2022-08-12
. 3- Benign phenotype (with low harm avoidance and high novelty seeking, reward dependence and persistence traits clustered with lower symptom severity and low impulsivity) .
. 3- Benign phenotype (with low harm avoidance and high novelty seeking, reward dependence and persistence traits clustered with lower symptom severity and low impulsivity) .
-
Stroke: In addition to cerebrovascular problems, other causes of stroke are these!
Time of Update: 2022-08-12
stroke managementThis study was a retrospective analysis of a prospective, multicenter, nationwide registry, the Korea National Institutes of Health Stroke Clinical Research Center Registry .
stroke managementThis study was a retrospective analysis of a prospective, multicenter, nationwide registry, the Korea National Institutes of Health Stroke Clinical Research Center Registry .
-
J Headache Pain: The second cause of disabling, the blasting migraine!
Time of Update: 2022-08-12
Summaryabstract abstractAccording to the Global Burden of Disease (GBD) study, headache is one of the most prevalent and disabling diseases worldwide, including general headache, migraine and tension-
-
JNNP: Phase II study of ketogenic diet in relapsing multiple sclerosis, safety, tolerability and potential clinical benefit
Time of Update: 2022-08-12
Despite these well-established considerations, the clear imperative to include pediatric patients in studies is further underscored by data showing a strong association between childhood obesity and multiple sclerosis risk .
-
Neurology: Association of plaque inflammation with stroke recurrence in patients with unproven benefit from carotid revascularization
Time of Update: 2022-08-12
The validated SCAIL score, which includes stenosis severity and inflammation as measured by positron emission tomography (PET), improved identification of patients with recurrent stroke compared with luminal stenosis alone .
-
Molecular Psychiatry: A common pattern of functional vulnerability associated with emotion processing in the frontotemporal lobar degeneration spectrum
Time of Update: 2022-08-12
. Elisa Canu et al investigated the relationship between emotional processing and resting-state functional connectivity (rs-FC) in brain networks in frontotemporal lobar degeneration (FTLD) .
. Elisa Canu et al investigated the relationship between emotional processing and resting-state functional connectivity (rs-FC) in brain networks in frontotemporal lobar degeneration (FTLD) .
-
Aging Cell: Tsinghua Zhong Yi's research group reveals the molecular mechanism that memory is easily disturbed after aging
Time of Update: 2022-08-12
(Age-related memory vulnerability to interfering stimuli is caused by gradual loss of MAPK-dependent protection in Drosophila)The corresponding author of the paper is Assistant Researcher Li Qian (Professor Zhong Yi's research group) at the School of Life Sciences, Tsinghua University .
-
Stroke: New discoveries in the field: 14-year follow-up of small vessel disease, what is the dynamic change process?
Time of Update: 2022-08-12
SVD shows marked progression over time, but mild WMH rarely progresses to clinically severe WMH Original source: Cai M, Jacob MA, van Loenen MR, et al.
SVD shows marked progression over time, but mild WMH rarely progresses to clinically severe WMH Original source: Cai M, Jacob MA, van Loenen MR, et al.
-
JPD: Apathy reflects extrastriatal dopaminergic degeneration in new-onset Parkinson's disease
Time of Update: 2022-08-12
Isolated patients with Parkinson's disease are associated with extrastriatal dopaminergic degeneration Original source: Sampedro, F.
Isolated patients with Parkinson's disease are associated with extrastriatal dopaminergic degeneration Original source: Sampedro, F.
Isolated patients with Parkinson's disease are associated with extrastriatal dopaminergic degeneration Original source: Sampedro, F.
-
Scientists introduce AI meta-learning into neuroscience for the first time, promising to improve brain imaging precision medicine
Time of Update: 2022-08-12
This research is the first to introduce meta-learning methods in the field of artificial intelligence into the field of neuroscience and medicine, which can train reliable AI models on limited medical data and improve the effect of precision medicine based on brain imaging .
-
JPD: Neurodegeneration in the medial globus pallidus, closely related to dopa responses in freezing gait
Time of Update: 2022-08-12
Figure 2: The results of the paperFigure 2: The results of the paperThey found that patients with dopa-responsive FOG showed fractional anisotropy, a decrease in mean kurtosis (MK), and an increase in radial diffusivity in the right GPi compared with patients with dopa-responsive FOG .
-
Neurology: Snoring is a disease, positive pressure ventilation is a good choice
Time of Update: 2022-08-12
Since there are no effective treatments to prevent , cure or delay the progression of dementia, identifying treatable risk factors that increase the risk of dementia, such as obstructive sleep apnea (OSA), can provide insights into changing the occurrence or severity of dementia promising means .
-
Front. Aging Neurosci: Alzheimer's disease-related markers associated with physical activity levels in cognitively normal older adults
Time of Update: 2022-08-12
Aging Neurosci to evaluate the relationship between habitual physical activity levels and brain amyloid deposition and AD -related blood biomarkers in (APOE) ε4 carriers and non-carriers .
